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Dataset results
29 results for “Acute Mountain Sickness”
DataSet of "No renal dysfunction or salt and water retention in acute mountain sickness at 4,559 m among young resting males after passive ascent"
<p><strong>Abstract</strong></p> <p><strong>Purpose</strong>: This study examined the role and function of the kidney at high altitude in relation to fluid balance and the development of acute mountain sickness (AMS), avoiding confounders that have contributed to conflicting results in previous studies.</p> <p><strong>Methods</strong>: We examined 18 healthy male volunteers (18 - 40 years) not acclimatized to high altitude while on a controlled diet and resting recumbently for 24 h at Lausanne (altitude: 560 m) followed by a period of 44 hours after reaching the Regina Margherita hut (4,559 m) by helicopter.</p> <p><strong>Results</strong>: AMS scores peaked after 20 h at 4,559 m. AMS was defined as functional Lake Louise score <span class="math-tex">\({\ge}\)</span> 2.There were no significant differences between 10 subjects with and 8 subjects without AMS for urinary flow, fluid balance and weight change. Sodium excretion rate was lower in those with AMS after 24 h at altitude. Microalbuminuria increased at altitude but not differently between the groups. Creatinine clearance was not affected by altitude or AMS, while sinistrin and PAH clearances decreased slightly, more markedly in those without AMS. Plasma concentrations of epinephrine, norepinephrine, atrial natriuretic factor and vasopressin increased while renin activity, angiotensin and aldosterone decreased at altitude. Hormones levels did not differ between those with and without AMS.</p> <p><strong>Conclusions</strong>: 1) Renal function is not affected by hypoxia at 4,559 m in resting subjects except for minor microalbuminuria, 2) high altitude diuresis does not occur and 3) AMS is not associated with salt and water retention or renal dysfunction.</p>
The Effect of Chronic Nitrate Supplementation on Acute Mountain Sickness and Exercise Performance in Hypoxia
ClinicalTrials.gov study NCT03101904. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Inhaled Budesonide and Acute Mountain Sickness
ClinicalTrials.gov study NCT02811016. IPD Sharing: NO. Countries: 1. Publications: 1.
Anti-Oxidant Supplementation for the Prevention of Acute Mountain Sickness
ClinicalTrials.gov study NCT00664001. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Erythropoietin in the Prevention of Acute Mountain Sickness
ClinicalTrials.gov study NCT01665781. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Comparison of Metoclopramide and Ibuprofen for the Treatment of Acute Mountain Sickness
ClinicalTrials.gov study NCT01522326. IPD Sharing: UNDECIDED. Countries: 1. Publications: 17.
Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention
ClinicalTrials.gov study NCT01060969. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Acetazolamide on Acute Mountain Sickness in Lowlanders Older Than 40 Years
ClinicalTrials.gov study NCT03561675. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Can Rhodiola Crenulata Intake Improve Oxygen Saturation and Decrease the Incidence of Acute Mountain Sickness
ClinicalTrials.gov study NCT01536288. IPD Sharing: Not stated. Countries: 1. Publications: 29.
Controlled Hyperventilation as Prophylaxis for Acute Mountain Sickness
ClinicalTrials.gov study NCT02972411. IPD Sharing: NO. Countries: 1. Publications: 10.
Prochlorperazine Maleate Versus Placebo for the Prophylaxis of Acute Mountain Sickness
ClinicalTrials.gov study NCT06450899. IPD Sharing: NO. Countries: 1. Publications: 1.
Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness
ClinicalTrials.gov study NCT06310642. IPD Sharing: NO. Countries: 1. Publications: 8.
Data from: Ginkgo biloba extract for prevention of acute mountain sickness: a systematic review and meta-analysis of randomized controlled trials
Study objective: Trials of ginkgo biloba extract (GBE) for the prevention of acute mountain sickness (AMS) have been published since 1996. Because of their conflicting results, the efficacy of GBE remains unclear. We performed a systematic review and meta-analysis to assess whether GBE prevents acute mountain sickness. Methods: The Cochrane Library, EMBASE, Google Scholar, and PubMed databases were searched for articles published up to May 20, 2017. Only randomized controlled trials were included. AMS defined as acute mountain sickness–cerebral(AMS-C) score≧0.7 or Lake Louise Score (LLS)≧3 with headache. The main outcome measures were the relative risks of AMS in participants receiving GBE for prophylaxis. Meta-analyses were conducted using random-effects models. Sensitivity analyses, subgroup analyses and tests for publication bias were conducted. Results: Six published articles with a total of 451 participants met all eligibility criteria. In the primary meta-analysis of all 7 study groups, GBE showed trend of AMS prophylaxis, but it is not statistically significant (RR =0.68; 95% CI: 0.45 to 1.04; p-value=0.08) (Figure 2). The I2 statistic was 58.7% (p-value=0.02), indicating substantial heterogeneity. The results of subgroup analyses of studies with low risk of bias, low starting altitude (<2500 m), number of treatment days before ascending and dosage of GBE were similar. Conclusions: The currently available data suggest that although GBE may tend toward AMS prophylaxis, there are not enough data to show the statistically significant effect of GBE for preventing AMS. Further large randomized control studies are warranted.
Voluntary Isocapnic Hyperpnea in Hypoxia to Mitigate Acute Mountain Sickness
ClinicalTrials.gov study NCT07126834. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy of Positive Expiratory Pressure on Acute Mountain Sickness
ClinicalTrials.gov study NCT07148674. IPD Sharing: NO. Countries: 0. Publications: 15.
Data from: Ginkgo biloba extract for prevention of acute mountain sickness: a systematic review and meta-analysis of randomized controlled trials
Open the record for dataset details and reuse information.
IL-10 dysregulation in acute mountain sickness revealed by transcriptome analysis
GEO Series GSE75665. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
The Effect of Continuous Positive Pressure Ventilation on Symptoms of Acute Mountain Sickness
ClinicalTrials.gov study NCT06145113. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
HighCycle Study: Effect of High Altitude on Acute Mountain Sickness in Women Related to Their Menstrual Cycle Phase
ClinicalTrials.gov study NCT06499714. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Study of Compound Danshen Dripping Pills to Treat Acute Mountain Sickness
ClinicalTrials.gov study NCT03270787. IPD Sharing: NO. Countries: 1. Publications: 0.
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