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3 results for “BLT1”
Raw diffraction images of leukotriene B4 receptor BLT1
<p>Diffraction images of Leukotriene B<sub>4</sub> receptor (BLT1) in complex with antagonist BIIL260, a chemical bearing a benzamidine moiety. BLT1 is one of class-A G-protein coupled receptor (GPCR), and the bound benzamidine moiety mimics a sodium ion-centered water cluster of BLT1 that is considered to exist in many class-A GPCRs. The bound benzamidine moiety stabilizes the inactive state of BLT1, and BIIL260 exhibits the characteristics of an inverse agonist for BLT1.</p> <p>Small-wedge (1296 crystals, 2.5°/crystal) datasets collected from loop-harvested microcrystals using EIGER X 9M detector at a wavelength of 1 Å on BL32XU, SPring-8. The crystals belonged to space group P22<sub>1</sub>2<sub>1</sub> with unit cell parameters a=69.6, b=77.6, c=135.5 Å.</p> <p>Finally, 494 datasets were merged at 3.7 Å resolution in the published result (Hori et al. Nature Chemical Biology, 2018; PDB code: 5X33) using KAMO; see processing note https://github.com/keitaroyam/yamtbx/wiki/Processing-BLT1-data-(5X33)</p> <p>Note</p> <ul> <li>The master.h5 files were modified; see https://github.com/keitaroyam/yamtbx/blob/master/doc/eiger-en.md</li> <li>To further reduce total file size, flatfield data of master.h5 were removed and saved in a file in each directory (linked from master.h5 files).</li> <li>Most frames have lipid rings.</li> </ul>
Effects of BLT1 inhibition in a mouse model of liver fibrosis
GEO Series GSE248273. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing.
scRNA-Seq of immune populations from nasal mucosa and lungs of C57BL/6 mice and BLT1 receptor deficient mice infected intranasally with MCMV K181 strain
GEO Series GSE306035. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing; Other.
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.