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41 results for “Bartonella”
Fig. 2 in First description of Bartonella koehlerae infection in a Spanish dog with infective endocarditis
Fig. 2 Endocardium. Mixed infhammatoru and fibrinous exudate associated to a bacteriah cohonu (white arrow). H&E staininc (×200). Scale-bar: 40 μm
Fig. 3 in First description of Bartonella koehlerae infection in a Spanish dog with infective endocarditis
Fig. 3 Endocardium. Fibrinous and neutrophihic exudation accompanied sith intense fibrovascuhar reactivitu (bottom richt). H&E staininc (×400). Scale-bar: 40 μm
Fig. 4 in First description of Bartonella koehlerae infection in a Spanish dog with infective endocarditis
Fig. 4 Evohutionaru rehationships of taxa. The evohutionaru historu sas inferred usinc the Neichbor-Joininc method. The optimah tree is drasn to scahe, sith branch hencths (next to the branches) in the same units as those of the evohutionaru distances used to infer the phuhocenetic tree. The evohutionaru distances sere computed usinc the Maximum Composite Likehihood method and are in the units of the number of base substitutions per site
Fig. 2 in Investigation of Bartonella spp. in brazilian mammals with emphasis on rodents and bats from the Atlantic Forest
Fig. 2. Phylogenetic relationships within the Bartonella genus based on the groEL gene. The tree was inferred by using the Maximum Likelihood (ML) and Bayesian inference (BI) with the HKY + I + G model. The nodal support is described at the left by bootstrap replicates and at the right by posterior probability to each node represented. The symbol of one asterisk (*) indicates low nodal support in ML or BI, and the symbol of two asterisk (**) indicates incongruence between ML and BI. The sequences detected in the present study are described in red and the sequences of previous studies of Brazilian genotypes in blue. The highlighted clades represented the genotypes described to Brazil. The clade E, F and G represent the genotypes obtained in this study. Brucella abortus and Ca. Tokpelaia hoelldoblerii was used as an outgroup. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Fig. 3 in Investigation of Bartonella spp. in brazilian mammals with emphasis on rodents and bats from the Atlantic Forest
Fig. 3. Phylogenetic relationships within the Bartonella genus based on the ftsZ gene. The tree was inferred by using the Maximum Likelihood (ML) and Bayesian inference (BI) with the GTR + I + G model. The nodal support is described at the left by bootstrap replicates and at the right by posterior probability to each node represented. The symbol of one asterisk (*) indicates low nodal support in ML or BI, and the symbol of two asterisk (**) indicates incongruence between ML and BI. The sequences detected in the present study are described in red and the sequences of previous studies of Brazilian genotypes in blue. The highlighted clades represented the genotypes described to Brazil. The clade H, I, J, K and L represent the genotypes obtained in this study. Brucella abortus and Ca. Tokpelaia hoelldoblerii was used as an outgroup. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Fig. 1 in Investigation of Bartonella spp. in brazilian mammals with emphasis on rodents and bats from the Atlantic Forest
Fig. 1. Phylogenetic relationships within the Bartonella genus based on the gltA gene. The tree was inferred by using the Maximum Likelihood (ML) and Bayesian inference (BI) with the GTR + I + G model. The nodal support is described at the left by bootstrap replicates and at the right by posterior probability to each node represented. The symbol of one asterisk (*) indicates low nodal support in ML or BI, and the symbol of two asterisk (**) indicates incongruence between ML and BI. The sequences detected in the present study are described in red and the sequences of previous studies of brazilian genotypes in blue. The highlighted clades represented the genotypes described to Brazil. The clade A, B, C and D represent the genotypes obtained in this study. Brucella abortus and Ca. Tokpelaia hoelldoblerii was used as an outgroup. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Fig. 2 in Bartonella, Blechomonas and Trypanosoma in fleas from the long-tailed ground squirrel (Spermophilus undulatus) in northwestern China
Fig. 2. Phylogenetic tree of (A) Bartonella (gltA gene) and (B) Trypanosomatidae (18S rRNA gene) from the LTGR fleas (NJ; bootstrap replicates: 1000). The new sequences provided in the present study are indicated by a black circle (followed by the accession number).
Fig. 2 in Molecular detection of Bartonella rochalimae and Hepatozoon canis in red foxes (Vulpes vulpes) from China
Fig. 2. The NJ phylogenetic tree of the 18S rRNA of Hepatozoon spp. (NJ; bootstrap replicates: 1000). Branch lengths correlate to the number of substitutions inferred according to the scale shown. Sequences of obtained in this study are indicated by solid cycle (●).
Fig. 1 in Molecular detection of Bartonella rochalimae and Hepatozoon canis in red foxes (Vulpes vulpes) from China
Fig. 1. The NJ phylogenetic tree of the gltA-rpoB concatenated sequences of Bartonella spp. (NJ; bootstrap replicates: 1000). Branch lengths correlate to the number of substitutions inferred according to the scale shown. Sequences of obtained in this study are indicated by solid cycle (●).
Data from: Genetic diversity, infection prevalence, and possible transmission routes of Bartonella spp. in vampire bats
Bartonella spp. are globally distributed bacteria that cause endocarditis in humans and domestic animals. Recent work has suggested bats as zoonotic reservoirs of some human Bartonella infections; however, the ecological and spatiotemporal patterns of infection in bats remain largely unknown. Here we studied the genetic diversity, prevalence of infection across seasons and years, individual risk factors, and possible transmission routes of Bartonella in populations of common vampire bats (Desmodus rotundus) in Peru and Belize, for which high infection prevalence has previously been reported. Phylogenetic analysis of the gltA gene for a subset of PCR-positive blood samples revealed sequences that were related to Bartonella described from vampire bats from Mexico, other Neotropical bat species, and streblid bat flies. Sequences associated with vampire bats clustered significantly by country but commonly spanned Central and South America, implying limited spatial structure. Stable and nonzero Bartonella prevalence between years supported endemic transmission in all sites. The odds of Bartonella infection for individual bats was unrelated to the intensity of bat flies ectoparasitism, but nearly all infected bats were infested, which precluded conclusive assessment of support for vector-borne transmission. While metagenomic sequencing found no strong evidence of Bartonella DNA in pooled bat saliva and fecal samples, we detected PCR positivity in individual saliva and feces, suggesting the potential for bacterial transmission through both direct contact (i.e., biting) and environmental (i.e., fecal) exposures. Further investigating the relative contributions of direct contact, environmental, and vector-borne transmission for bat Bartonella is an important next step to predict infection dynamics within bats and the risks of human and livestock exposures.
Antibodies to Borrelia burgdorferi and Bartonella species in serum and synovial fluid from people with rheumatic diseases
<p>Vector-borne infections may underlie some rheumatic diseases, particularly in people with joint effusions. The aim of this study was to compare serum and synovial fluid antibodies to<em> B. burgdorferi </em>and <em>Bartonella </em>spp. in patients with rheumatic diseases.</p> <p>This observational, cross-sectional study examined paired synovial fluid and serum specimens collected from 110 patients with joint effusion between October 2017 and January 2022. Testing for antibodies to <em>B. burgdorferi </em>(using CDC criteria) and <em>Bartonella </em>spp. via two Indirect Fluorescent Antibody [IFA] assays, was performed as part of routine patient care.</p> <p>There were 30 participants (27%) with positive two-tier <em>B. burgdorferi</em> serology, and 26 participants (24%) with IFA seroreactivity (≥1:256) to <em>B. henselae </em>and/or <em>B. quintana. </em>Both <em>B. burgdorferi</em> IgM and IgG were detected more frequently in synovial fluid than serum: 27% of patients were either IgM or IgG positive in synovial fluid, compared to 15.5% in serum (p = 0.048). Conversely, <em>B. henselae </em>and <em>B. quintana </em>antibodies were detected more frequently in serum than synovial fluid; overall only 2% of patients had positive IFA titers in synovial fluid, compared to 24% who had positive IFA titers in serum (p <0.001). There were no significant associations between <em>B. burgdorferi</em> or <em>Bartonella</em> spp. seroreactivity with any of the clinical rheumatological diagnoses.</p> <p>This study provides preliminary support for the importance of synovial fluid antibody testing for documenting exposure to <em>B. burgdorferi</em>, but not for documenting exposure to <em>Bartonella </em>spp.</p>
Fig. 1 in Bartonella, Blechomonas and Trypanosoma in fleas from the long-tailed ground squirrel (Spermophilus undulatus) in northwestern China
Fig. 1. Map of northwestern China showing sampling sites and coordinates.
Feeding on a Bartonella henselae infected host triggers temporary changes in the Ctenocephalides felis microbiome
<p>The effect of <em>Bartonella</em> <em>henselae</em> on the microbiome of its vector, <em>Ctenocephalides</em> <em>felis</em> (the cat flea) is largely unknown, as a majority of <em>C. felis</em> microbiome studies have utilized wild-caught pooled fleas. Therefore, we surveyed the microbiome of laboratory-origin <em>C. felis</em> fed on <em>B. henselae-</em>infected cats to identify changes to microbiome diversity and microbe prevalence compared to unfed fleas, and fleas fed on uninfected cats. To evaluate changes over time, fleas were fed on cats for 24 hours or 9 days. Utilizing Next Generation Sequencing (NGS) on the Illumina platform, we documented an increase in microbial diversity, richness, and evenness in <em>C. felis</em> fed on <em>Bartonella</em>-infected cats for 24 hours, changes that returned to baseline (unfed fleas or fleas fed on uninfected cats) after 9 days on the host. The increased diversity in the <em>C. felis</em> microbiome when fed on <em>B. henselae</em>-infected cats may be related to the mammalian, flea, or endosymbiont response, factors that remain to be explored and potentially exploited for pathogen control. In addition, poor <em>B</em>. <em>henselae</em> acquisition was documented in these laboratory-maintained <em>C. felis</em>. Potential hypotheses to account for this finding include poor acquisition by adult fleas, the influence of flea genetic variation on <em>B. henselae</em> acquisition, and lack of co-feeding with <em>B. henselae</em>-infected <em>C. felis</em>. This study provides an investigation of the <em>C. felis</em> microbiome response to blood feeding and blood-feeding on <em>B. henselae</em>-infected cats; however, future studies are necessary to fully characterize the effect of endosymbionts and <em>C. felis</em> diversity on <em>B. henselae</em> acquisition.</p>
Data from: Bartonella infections are prevalent in rodents despite efficient immune responses
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Data from: Genetic diversity, infection prevalence, and possible transmission routes of Bartonella spp. in vampire bats
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Feeding on a Bartonella henselae infected host triggers temporary changes in the Ctenocephalides felis microbiome
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Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma species in dogs with hemangiosarcoma from across the United States
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Antibodies to Borrelia burgdorferi and Bartonella species in serum and synovial fluid from people with rheumatic diseases
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................................................................................................................................................. Fig. 3. SDSPAGE analysis of total bacterial protein extracts of the four roe deer isolates as well as other Bartonella species. Extracts of total bacterial protein were separated by SDSPAGE and stained with Coomassie brilliant blue. Lanes: M, molecular mass markers; 1, R1T; 2, R3; 3, R4; 4, R6; 5, Bartonella henselae; 6, Bartonella quintana; 7, Bartonella bacilliformis; 8, Bartonella elizabethae; 9, Bartonella clarridgeiae; 10, Bartonella alsatica; 11, Bartonella tribocorum; 12, Bartonella grahamii. in Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer.
................................................................................................................................................. Fig. 3. SDSPAGE analysis of total bacterial protein extracts of the four roe deer isolates as well as other Bartonella species. Extracts of total bacterial protein were separated by SDSPAGE and stained with Coomassie brilliant blue. Lanes: M, molecular mass markers; 1, R1T; 2, R3; 3, R4; 4, R6; 5, Bartonella henselae; 6, Bartonella quintana; 7, Bartonella bacilliformis; 8, Bartonella elizabethae; 9, Bartonella clarridgeiae; 10, Bartonella alsatica; 11, Bartonella tribocorum; 12, Bartonella grahamii.
................................................................................................................................................. Fig. 5. Phylogenetic tree based on 16S rRNA sequences (a) and gltA sequences (b) showing the position of strains R1T, R3, R4 and R6 in relation to the known Bartonella spp. The tree was rooted by using Brucella abortus (a) and Sinorhizobium meliloti (b) as the outgroup. in Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer.
................................................................................................................................................. Fig. 5. Phylogenetic tree based on 16S rRNA sequences (a) and gltA sequences (b) showing the position of strains R1T, R3, R4 and R6 in relation to the known Bartonella spp. The tree was rooted by using Brucella abortus (a) and Sinorhizobium meliloti (b) as the outgroup.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.