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34 results for “Biomedical research”

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zenodo48/100

MiRoR15-P2-Development of ARCADIA: a tool for assessing the quality of peer-review reports in biomedical research

<p>Survey questionnaire, anonymised survey data, and codebook related to: Superchi C, Hren D, Blanco D, Rius R, Recchioni A, Boutron I, Gonz&aacute;lez JA. Development of ARCADIA: a tool for assessing the quality of peer-review reports in biomedical research. BMJ Open 2020;0:e035604. doi:10.1136/bmjopen-2019-035604</p>

opencc-by-4.0Aug 2020View details →
zenodo48/100

Is the winner really the best? A critical analysis of common research practice in biomedical image analysis competitions

<p>This data set corresponds to the paper: Is the winner really the best? A critical analysis of common research practice in biomedical image analysis competitions [1] (Experiment: Comprehensive reporting).</p> <p>The key research questions corresponding to this data set were:</p> <p>RQ1: What is the role of challenges for the field of biomedical image analysis (e.g. How many challenges conducted to date? In which fields? For which algorithm categories? Based on which modalities?)</p> <p>RQ2: What is common practice related to challenge design (e.g. choice of metric(s) and ranking methods, number of training/test images, annotation practice etc.)? Are there common standards?</p> <p>RQ3: Does common practice related to challenge reporting allow for reproducibility and adequate interpretation of results?</p> <p>To address these research questions, we aimed to capture all biomedical image analysis challenges that have been conducted up to 2016. To acquire the data, we analyzed the websites hosting/representing biomedical image analysis challenges, namely grand-challenge.org, dreamchallenges.org and kaggle.com as well as websites of main conferences in the field of biomedical image analysis, namely Medical Image Computing and Computer Assisted Intervention (MICCAI), International Symposium on Biomedical Imaging (ISBI), International Society for Optics and Photonics (SPIE) Medical Imaging, Cross Language Evaluation Forum (CLEF), International Conference on Pattern Recognition (ICPR), The American Association of Physicists in Medicine (AAPM), the Single Molecule Localization Microscopy Symposium (SMLMS) and the BioImage Informatics Conference (BII). This yielded a list of 150 challenges with 549 tasks.</p> <p>Next, a tool for instantiating the challenge parameter list introduced in [1] was used by some of the authors (engineers and medical student) to formalize all challenges that met our inclusion criteria as follows: (1) Initially, each challenge was independently formalized by two different observers. (2) The formalization results were automatically compared. In ambiguous cases, when the observers could not agree on the instantiation of a parameter - a third observer was consulted, and a decision was made. When refinements to the parameter list were made, the process was repeated for missing values. Based on the formalized challenge data set, a descriptive statistical analysis was performed to characterize common practice related to challenge design and reporting.</p> <p>[1] Maier-Hein, L., Eisenmann, M., Reinke, A., Onogur, S., Stankovic, M., Scholz, P., Arbel, T., Bogunovic, H., Bradley, A. P., Carass, A., Feldmann, C., Frangi, A. F., Full, P. M., van Ginneken, B., Hanbury, A., Honauer, K., Kozubek, M., Landman, B. A., M&auml;rz, K., Maier, O., Maier-Hein, K., Menze, B. H., M&uuml;ller, H., Neher, P. F., Niessen, W., Rajpoot, N., Sharp, G. C., Sirinukunwattana, K., Speidel, S., Stock, C., Stoyanov, D., Aziz Taha, A., van der Sommen, F., Wang, C.-W., Weber, M.-A., Zheng, G., Jannin, P., Kopp-Schneider, A.: Is the winner really the best? A critical analysis of common research practice in biomedical image analysis competitions. arXiv preprint arXiv:1806.02051 (2018).</p>

opencc-by-4.0Jun 2018View details →
zenodo44/100

A high-throughput 3D X-ray histology facility for biomedical research and preclinical applications - Supplementary Data

<p><strong>Videos</strong></p><ul><li><strong>Video 1</strong> A video going through the Z stack in single slices. This is a cross- sectional view of the XRH image stack along the XY plane. XRH datasets are normally oriented (resliced) in a way that a scroll through the stack along the XY plane emulates the physical histology slicing of the tissue.</li><li><strong>Video 2 </strong>A video going through the Y stack in single slices. This is a cross- sectional view of the XRH image stack along the XZ plane. XRH datasets are normally oriented (resliced) in a way that a scroll through the stack along the XY plane emulates the physical histology slicing of the tissue.</li><li><strong>Video 3 </strong>A video going through the X stack in single slices. This is a cross- sectional view of the XRH image stack along the YZ plane. XRH datasets are normally oriented (resliced) in a way that a scroll through the stack along the XY plane emulates the physical histology slicing of the tissue.</li><li><strong>Video 4 </strong>3D X-ray histology (XRH) is a µCT -based workflow tailored to fit seamlessly into current histology workflows in biomedical and pre-clinical research, as well as clinical histopathology. Microanatomical detail can be captured from standard (non-stained) formalin-fixed and paraffin-embedded (FFPE) tissue blocks.</li><li><strong>Video 5</strong> Average Intensity Projection (AIP) of the sample through the Histologically relevant plane. This is a 2D visualisation rendering the Average Intensity of 20x single XY slices along the z-axis of the stack. XRH datasets are normally oriented (resliced) in a way that a scroll through the stack along the XY plane emulates the physical histology slicing of the tissue.</li><li><strong>Video 6 </strong>Maximum Intensity Projection (MIP) of the sample through the Histologically relevant plane. This is a 2D visualisation rendering the Maximum Intensity of 20x single XY slices along the z-axis of the stack. XRH datasets are normally oriented (resliced) in a way that a scroll through the stack along the XY plane emulates the physical histology slicing of the tissue.</li><li><strong>Video 7 </strong>Standard deviation projection of the sample going through the histologically relevant plane. This is a 2D visualisation rendering the Standard Deviation of 20x single XY slices along the z- axis of the stack. XRH datasets are normally oriented (resliced) in a way that a scroll through the stack along the XY plane emulates the physical histology slicing of the tissue.</li></ul><p><i>* <strong>Videos 5 -7</strong> are also referred to as "thick-slice rolls" </i>-&nbsp;<i>Thick-slice rolling is a 2D thick-slice viewing that allows rolling of a pre-selected number of slices (n) along the z-axis of the 3D data. A single thick-slice roll forwards is accomplished by translating the thick-slice by one single slice forwards; that is moving forward by one (+1) slice from the first and nth element and reapplying the criteria or operations to the new slice sub-stack.</i><br>&nbsp;</p><p><strong>The questionnaire used to collect feedback about the needs of the XRH community.</strong></p><ul><li>Survey.docx</li><li>Survey.pdf</li></ul><p><br><strong>Exemplar report of a semi-automatically generated augmented PDF file</strong> that contain sample information, imaging settings, still images with descriptive figure legends, and links to corresponding online videos</p><ul><li>DEMO02019-FFPE_report_99EbPXG.pdf</li></ul><p>&nbsp;</p><p>= = = = = = = = = = = = = = = =&nbsp;<br><strong>System performance data ZIP</strong><br>= = = = = = = = = = = = = = = = &nbsp;</p><p>This ZIP file contains imaging data collected through different systems and setups at the XRH facility at the μ-VIS X-ray Imaging Centre at the University of Southampton for the purpose of acceptance and/or system performance characterisation. Below is an overview of the folder structure and its contents</p><p>The following files are X-ray imaging data collected on September 28, 2017, using the Med-X system and a Jima phantom at 55 kV peak and 7 Watts.&nbsp;</p><ul><li>20170928_MEDX_1642_JIMA_55kVp7W-2.tif</li><li>20170928_MEDX_1642_JIMA_55kVp7W.tif</li><li>20170928_MEDX_1642_JIMA_55kVp7W.tif.profile.xml</li></ul><p>This PDF document is related to a QRM MicroCT bar pattern phantom, and its specifications</p><ul><li>QRM-MicroCT-Barpattern-Phantom.pdf</li></ul><p>Graphs showing the calculated focal-spot size as a function of the X-ray power (W) for the Molybdenum rotating target calculated using Edge Modulation function testing. The performance is then compared with the performance of the Reflection target across the same range of powers. Raw data can be found in XRH_QRM_Refl-vs-Rot-TargetComparison_SingleReconSlices_5umPixelSize folder. Test performed in July 2021. &nbsp;</p><ul><li>XRH_202107_MoRot-testing_EdgeModFunction-QRMrecons+RotReflCompar.png</li></ul><p>&nbsp;</p><p><i><strong>/ XRH-XT-H-225-ST_FocalSpots</strong></i><br>This directory contains radiographic data collected using the XRH system with a JIMA phantom and MoRt (Molybdenum rotating), TT (Transmission), and Reflection targets.</p><ul><li>20200113_XRH_Jima test MoRT 55kV 15W.tif, 20200113_XRH_Jima test MoRT 55kV 30W.tif, etc.:&nbsp;<br>These files represent radiographs taken on January 13, 2020, using the XRH system, Jima phantom, MoRT target at 55 kVp and varying wattages.</li><li>20200207_XRH_JIMA 80kV TT1a.tif, 20200207_XRH_JIMA 80kV TT1b.tif, etc.<br>Similar to the above, these files are from February 7, 2020, and use 80 kVp with a TT target.</li><li>20231115_XRH_reflW_80kVp6W.tif, 20231115_XRH_reflW_80kVp6W_02.tif, etc.<br>These files are from November 15, 2023, and collected using the XRH system with a Reflection target at 80 kVp and 6 Watts.</li></ul><p><i><strong>/ XRH_QRM_Refl-vs-Rot-TargetComparison_SingleRadioFromCTs_5umPixelSize</strong></i><br>This directory contains single radiographs taken with a pixel size of 5 micrometers using the Molybdenum rotating (MoRt), and the Reflection target using tungsten (W) and Molybdenum (Mo) metals.</p><p><i><strong>/ XRH_QRM_Refl-vs-Rot-TargetComparison_SingleReconSlices_5umPixelSize</strong></i><br>This directory contains sinlge reconstruction slices of the setups mentioned above. Slices are exported from CT volumes and were used for the Edge Modulation function study. &nbsp;</p><p>For interpretation of the filenames in the folders listed above please see below and refer to specific files and folders for detailed information and results related to each imaging session:</p><ul><li><i>&lt;xx&gt;kVp or &lt;xx&gt;kV &nbsp;&nbsp;</i>:Imaging at a peak voltage of &lt;xx&gt; kVp.</li><li><i>&lt;y&gt;W</i> &nbsp; :Imaging at &lt;y&gt; Watts;<i>&nbsp; </i>"." is represented with "-"; i.e. 20210705_XRH_2766_PJB_TEST03552-EQPMT_W_6-9W is acquired using a power of 6.9 W</li><li><i>MoRt, TT, Refl&nbsp;</i> &nbsp;:Molybdenum, Transmission, and Reflection targets, respectively.</li><li><i>_W_ and _Mo_&nbsp;</i> &nbsp;:Tungsten and Molybdenum target materials.</li><li><i>_horiz</i> &nbsp; :Reconstruction slices in line with the X-ray beam's propagation direction.</li><li><i>_vert</i> &nbsp; :Reconstruction slices normal to the X-ray beam's propagation direction and parallel to the detector plane.</li></ul>

opencc-by-4.0Jun 2023View details →
zenodo44/100

A study on biomedical researchers' perspectives on public engagement in Southeast Asia

<p>Survey data from biomedical researchers in Southeast Asia about their perceptions of public engagement. The survey used open and closed questions.</p>

opencc-by-4.0Feb 2023View details →
zenodo44/100

A study on biomedical researchers' perspectives on public engagement in Southeast Asia

<p>Qualitative data on researcher&#39;s perceptions of public and community engagement in South and Southeast Asia</p>

opencc-by-4.0Apr 2023View details →
zenodo44/100

A high-throughput 3D X-ray histology facility for biomedical research and preclinical applications - Underlying Data

<p><strong>Video files and logs</strong></p> <p>Single-slice and thick-slice roll* source videos are included. Each video is accompanied by a .txt log that contains information about the source file, slice thickness, and a brief description of the visualization mode.</p> <p>List of files:</p> <ul> <li>20211019-23h59m_20xAvgInt.mp4</li> <li>20211019-23h59m_20xAvgInt.txt</li> <li>20211019-23h59m_20xMaxInt.mp4</li> <li>20211019-23h59m_20xMaxInt.txt</li> <li>20211019-23h59m_20xStDev.mp4</li> <li>20211019-23h59m_20xStDev.txt</li> <li>20211019-23h59m_XYSliceRoll.mp4</li> <li>20211019-23h59m_XYSliceRoll.txt</li> <li>20211019-23h59m_XZSliceRoll.mp4</li> <li>20211019-23h59m_XZSliceRoll.txt</li> <li>20211019-23h59m_YZSliceRoll.mp4</li> <li>20211019-23h59m_YZSliceRoll.txt</li> </ul> <p>*&nbsp;<em>Thick-slice rolling is a 2D thick-slice viewing that allows rolling of a pre-selected number of slices (n) along the z-axis of the 3D data. A single thick-slice roll forwards is accomplished by translating the thick-slice by one single slice forwards; that is moving forward by one (+1) slice from the first and nth element and reapplying the criteria or operations to the new slice sub-stack.</em></p> <p><strong>Volume XRH data</strong><br> These are processed raw volume file saved in .raw and/or .tiff format, which are resliced to a histology-relevant orientation and/or have been enhanced using noise reduction (3D median filter) and/or ct-artefact removal techniques (e.g. cBC identifies a bandpass filter used to remove intensity variations originating from the histology cassette).</p> <p>List of volume files:</p> <ul> <li><strong>32220_20200703_XRH_2504_OLK_DEMO02019-FFPE_1620x1959x164x16bit.raw</strong> <ul> <li>sample: Human lung adenocarcinoma</li> <li>histology-relevant resliced volume (2x2x2 3D medial filter applied)</li> <li>import as 1620 x 1959 x 164 x 16-bit, big-endian; voxel edge size (mm): 0.0160042 isotropic</li> </ul> </li> <li><strong>cBC_32220_20200703_XRH_2504_OLK_DEMO02019-FFPE_1588x1674x164x16bit.raw</strong> <ul> <li>sample: Human lung adenocarcinoma</li> <li>cassette artefacts background correction (bandpass) of volume 32220_20200703_XRH_2504_OLK_DEMO02019-FFPE_1620x1959x164x16bit.raw</li> <li>import as 1620 x 1959 x 164 x 16-bit, big-endian; voxel edge size (mm): 0.0160042 isotropic</li> </ul> </li> <li><strong>Med3D_HPass_2111_20190606_MEDX_2234_EH_HN2_recon_2000x1952x501x32bit.raw</strong> <ul> <li>sample: Human head and neck tumour</li> <li>histology-relevant resliced volume (1x1x1 3D medial filter applied)</li> <li>import as 2000 x 1952 x 501 x 32-bit, big-endian; voxel edge size (mm): 0.00999782 isotropic</li> </ul> </li> </ul> <p><strong>Conventional Histology and correlative imaging</strong></p> <ul> <li><strong>HN2_Level001_MEDX080_Manual_BW_Series4.tif</strong> <ul> <li>H&amp;E histology slice of the human head and neck tumour sample shown in &quot;Med3D_HPass_2111_20190606_MEDX_2234_EH_HN2_recon_2000x1952x501x32bit.raw&quot;</li> </ul> </li> <li><strong>HN2_Level001_MEDX080_Manual_BW</strong> <ul> <li>manual landmark selection used for registering the conventional histology slice onto the &mu;CT slice</li> </ul> </li> <li><strong>HN2_MEDX_rotated_0080.tif</strong> <ul> <li>Slice 80 from volume &quot;Med3D_HPass_2111_20190606_MEDX_2234_EH_HN2_recon_2000x1952x501x32bit.raw&quot; that corresponds to histological slice &quot;HN2_Level001_MEDX080_Manual_BW&quot;</li> </ul> </li> </ul>

opencc-by-4.0Jun 2023View details →
zenodo40/100

Data for: Wikipedia as a gateway to biomedical research

<p>Wikipedia has been described as a gateway to knowledge. However, the extent to which this gateway ends at Wikipedia or continues via supporting citations is unknown. This dataset was used&nbsp;to establish benchmarks for the relative distribution and referral (click) rate of citations, as indicated by presence of a Digital Object Identifier (DOI), from Wikipedia with a focus on medical citations.</p> <p>This data set includes for each day in August 2016 a listing of all DOI present in the English language version of Wikipedia and whether or not the DOI are biomedical in nature. Source Code for these data are available at: Ryan Steinberg. (2017, July 9). Lane-Library/wiki-extract: initial Zenodo/DOI release. Zenodo. http://doi.org/10.5281/zenodo.824813</p> <p>This dataset also includes a listing from Crossref DOIs that were referred from Wikipedia in August 2016 (Wikipedia_referred_DOI). Source code for these data sets is available at:&nbsp;Joe Wass. (2017, July 4). CrossRef/logppj: Initial DOI registered release. Zenodo. http://doi.org/10.5281/zenodo.822636&nbsp;</p> <p>An&nbsp;article based on this data was published in PLOS One:</p> <p>Maggio LA, Willinsky JM, Steinberg RM, Mietchen D, Wass JL, Dong T. Wikipedia as a gateway to biomedical research: The relative distribution and use of citations in the English Wikipedia. PloS one. 2017 Dec 21;12(12):e0190046.&nbsp;</p> <p>https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190046&nbsp;</p>

opencc-zeroJul 2017View details →
zenodo40/100

Data from the paper "The landscape of biomedical research"

<p>Data from the paper "<a href="https://www.cell.com/patterns/fulltext/S2666-3899(24)00076-X">The landscape of biomedical research</a>".</p> <p>The paper used the PubMed 2020 baseline (download date: 26.01.2021, not available anymore) supplemented with additional files from the 2021 baseline (download date: 27.04.2022, not available anymore), both originally obtained from <a href="https://www.nlm.nih.gov/databases/download/pubmed_medline.html">https://www.nlm.nih.gov/databases/download/pubmed_medline.html</a>, courtesy of the U.S. National Library of Medicine. This data can be found in v2 of this repository (<a href="../records/7849020">https://zenodo.org/records/7849020</a>).</p> <p>In the latest version of this repository we provide the PubMed 2024 baseline (download date: 06.02.2024) including all papers until the end of 2023, which is&nbsp;<strong>not</strong> the main data we analyzed in the paper but an updated version including newer articles. The paper contains two supplementary figures (S9 and S10) with the updated embedding.</p> <p>The latest version provided here includes the following files:</p> <p>pubmed_landscape_data_2024_v2.zip, which includes:</p> <p>- from the PubMed database: article title, journal, PMID, and publication year.</p> <p>- produced by us: t-SNE embedding X and Y coordinates, label, color, whether the paper is retracted or not (combining PubMed and Retraction Watch information), affiliation country ( from the first affiliation of the first author), and inferred gender (of both first and last author).</p> <p>(Note: pubmed_landscape_data_2024_v2.zip is identical to pubmed_landscape_data_2024.zip from v3 of this repository, but includes inferred genders additionally.)</p> <p>&nbsp;</p> <p>pubmed_landscape_abstracts_2024.zip, which includes:</p> <p>- from the PubMed database: PMID, and paper abstracts.</p> <p>&nbsp;</p> <p>PubMedBERT_embeddings_float16_2024.npy, which includes:</p> <p>- produced by us: PubMedBERT embeddings of the paper abstracts (numpy.ndarray of shape&nbsp;23,389,083x768).</p>

opencc-by-4.0Mar 2023View details →
zenodo36/100

Divergent Characteristics of Biomedical Research across Publication Types: A Quantitative Analysis on the Aging-related Research

<p>Attached in pdf here.</p>

opencc-by-4.0Dec 2023View details →
ClinicalTrials.gov36/100

Community Solutions to Adolescent Research Consent - Minor Consent for Biomedical HIV Research

ClinicalTrials.gov study NCT05371327. IPD Sharing: YES. Countries: 1. Publications: 2.

controlledIPD-YESFeb 2026View details →
zenodo32/100

Dataset: FAIR Biomedical Research Software (FAIR-BioRS) manuscript

<p>Data related to our FAIR-BioRS manuscript. More details are available at the associated GitHub repository: <a href="https://github.com/FAIR-BioRS/Data">https://github.com/FAIR-BioRS/Data</a>.&nbsp;</p>

opencc-by-4.0Jul 2023View details →
ClinicalTrials.gov32/100

BIRN (Biomedical Informatics Research Network) Resources Facilitate the Personalization of Malignant Brain Tumor

ClinicalTrials.gov study NCT01124461. IPD Sharing: Not stated. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov32/100

Criteria Associated With Patient Willingness to Participate in Biomedical Research

ClinicalTrials.gov study NCT03098303. IPD Sharing: Not stated. Countries: 1. Publications: 2.

restrictedIPD-UNDECIDEDFeb 2026View details →
dryad32/100

Data from: Qualitative study of physicians' varied uses of biomedical research in the USA

Open the record for dataset details and reuse information.

publicSep 2016View details →
dryad28/100

Research Data Management in Health and Biomedical Citizen Science: Practices and Prospects

<p><b>Background:</b> Public engagement in health and biomedical research is being influenced by the paradigm of citizen science. However, conventional health and biomedical research relies on sophisticated research data management tools and methods. Considering these, what contribution can citizen science make in this field of research? How can it follow research protocols and produce reliable results?</p> <p><b>Objective:</b> The aim of this paper is to analyse research data management practices in existing biomedical citizen science studies, so as to provide insights for members of the public and of the research community considering this approach to research.</p> <p><b>Methods:</b> A scoping review was conducted on this topic to determine data management characteristics of health and bio medical citizen science research. From this review and related web searching, we chose five online platforms and a specific research project associated with each, to understand their research data management approaches and enablers.</p> <p><b>Results:</b> Health and biomedical citizen science platforms and projects are diverse in terms of types of work with data and data management activities that in themselves may have scientific merit. However, consistent approaches in the use of research data management models or practices seem lacking, or at least are not evident.</p> <p><b>Conclusions:</b>  There is potential for important data collection and analysis activities to be opaque or irreproducible in health and biomedical citizen science initiatives without the implementation of a research data management model that is transparent and accessible to team members and to external audiences. This situation might be improved with participatory development of standards that can be applied to diverse projects and platforms, across the research data life cycle.<b> </b></p>

opencc-zeroSep 2020View details →
zenodo28/100

Figure 1 from: Conte M, Flynn AJ, Barrison P, Boisvert P, Landis-Lewis Z, Friedman C (2023) Digital objects to make computable biomedical knowledge FAIR: an infrastructural approach to knowledge representation, dissemination and implementation. Research Ideas and Outcomes 9: e109307. https://doi.org/10.3897/rio.9.e109307

Figure 1 Conceptual model of a Knowledge Object (KO) containing a payload, machine-actionable service and deployment specifications, metadata and a unique persistent identifier. We are exploring aligning our conceptual model with emerging best practices for FAIR Digital Objects. Derived from Wittenburg et al's Digital Objects as Drivers towards Convergence in Data Infrastructures (Wittenburg et al. 2019).

opencc-by-4.0Dec 2023View details →
zenodo28/100

Figure 3 from: Conte M, Flynn AJ, Barrison P, Boisvert P, Landis-Lewis Z, Friedman C (2023) Digital objects to make computable biomedical knowledge FAIR: an infrastructural approach to knowledge representation, dissemination and implementation. Research Ideas and Outcomes 9: e109307. https://doi.org/10.3897/rio.9.e109307

Figure 3 This figure illustrates the dual nature of Knowledge Objects: knowledge-as-resource and knowledge-as-service. A KO can be curated and maintained in a repository, pass metadata to a knowledge graph or deployed into applications. Different to other digital objects, the methods to deploy the KO to applications via custom or generic runtimes called by microservices are built into the KO.

opencc-by-4.0Dec 2023View details →
zenodo28/100

Figure 2 from: Conte M, Flynn AJ, Barrison P, Boisvert P, Landis-Lewis Z, Friedman C (2023) Digital objects to make computable biomedical knowledge FAIR: an infrastructural approach to knowledge representation, dissemination and implementation. Research Ideas and Outcomes 9: e109307. https://doi.org/10.3897/rio.9.e109307

Figure 2 (L) Sample KO as viewed from the KGrid Library, from which the KO can be implemented in a hosted runtime environment or downloaded. (R) Sample output results from deploying the KO.

opencc-by-4.0Dec 2023View details →
zenodo28/100

Harvard Biomedical Research Data Lifecycle

<p>The Biomedical Data Lifecycle is a representation of stages in your research regarding data collection, use, and storage. At&nbsp;the core is how to &quot;Store &amp; Manage&quot; the data for your project. How data is managed is integral to each stage in the diagram. Though the process is generally linear from &quot;Plan &amp; Design&quot; to &quot;Publish &amp; Reuse,&quot; you may find yourself jumping around this lifecycle throughout your project.&nbsp;For example, &quot;Data Management Plans&quot; are created at the planning stage but will be used throughout the research process in subsequent stages. The plan dictates how you will handle the data collected and created, and how you will share and disseminate that data, all while considering data documentation, safety, and reuse.&nbsp;</p> <p>This lifecycle diagram was created by the&nbsp;<a href="https://datamanagement.hms.harvard.edu/">Harvard Longwood Medical Area&nbsp;Research Data Management Working Group</a>.</p> <p><strong>RDM-lifecycle-v5.png</strong>: This&nbsp;diagram depicts the&nbsp;core stages of the research lifecycle.&nbsp;The center of the wheel has a grey circle labeled &quot;Store &amp; Manage.&quot; The second layer is cut into six segments labeled &quot;Plan &amp; Design&quot; in dark blue, &quot;Collect &amp; Create&quot; in light green, &quot;Analyze &amp; Collaborate&quot; in dark green, &quot;Evaluate &amp; Archive&quot; in gold, &quot;Share &amp; Disseminate&quot;&nbsp;in red, and &quot;Publish &amp; Reuse&quot; in orange. Guiding arrows are at the edge of each segment, showing the process to be continuous like a wheel. In this version, all segment labels are in title case, and the&nbsp;&quot;Evaluate &amp; Archive&quot; segment has been updated to gold to increase accessibility.</p> <p><strong>RDM-lifecycle-2tier-v5.png</strong>: This&nbsp;diagram includes an&nbsp;outer layer that represents the processes and concepts integral to each stage.&nbsp;The third layer expands the colors of each of the six sections and includes sub-elements of activities or resources that are involved in each of the six segments.&nbsp;In this version, all section labels are in title case, and the&nbsp;&quot;Evaluate &amp; Archive&quot; segment has been updated to gold to increase accessibility.</p> <p><strong>RDM-lifecycle-2tier-v5-template.ai</strong>: Adobe Illustrator&nbsp;template&nbsp;can be used to customize the outer second tier text and the number of segments 2, 3, or 4, to meet the needs of different schools or data groups. Complete instructions for using the template can be found in the <a href="https://zenodo.org/record/8075934">zip file included in version 2</a>. These materials are&nbsp;licensed under a&nbsp;<a href="http://creativecommons.org/licenses/by-nc/4.0/">Creative Commons Attribution-NonCommercial 4.0 International License</a>.</p>

opencc-by-nc-4.0Aug 2020View details →
ClinicalTrials.gov28/100

How Participants Perceive Biomedical Research in Pulmonology

ClinicalTrials.gov study NCT03397056. IPD Sharing: YES. Countries: 1. Publications: 0.

controlledIPD-YESFeb 2026View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record