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ShareScore release 0.9.0
Dataset results
37 results for “Cell type evolution”
A telencephalon cell type atlas for goldfish reveals diversity in the evolution of spatial structure and cell types
<p class="MsoNormal"><span>Teleost fish form the largest group of vertebrates, making them critically important for the study on the</span> <span>mechanisms of brain evolution. In fact, teleosts show a tremendous variety of adaptive behaviors similar</span> <span>to birds and mammals, however, the neural basis mediating these behaviors remains elusive. We</span> <span>performed a systematic comparative survey of the goldfish telencephalon: the seat of plastic behavior,</span> <span>learning, and memory in vertebrates. We delineated and mapped goldfish telencephalon cell types using</span> <span>single-cell RNA-seq and spatial transcriptomics, resulting in de novo molecular neuroanatomy</span> <span>parcellation. Glial cells were highly conserved across 450 million years of evolution separating mouse</span> <span>and goldfish, while neurons showed diversity and modularity in gene expression. Specifically,</span> <span>somatostatin (SST) interneurons, famously interspersed in the mammalian isocortex for local inhibitory</span> <span>input, were curiously aggregated in a single goldfish telencephalon nucleus, but molecularly conserved.</span> <span>Cerebral nuclei including the striatum, a hub for motivated behavior in amniotes, had molecularly conserved goldfish homologs. We further suggest different elements of a hippocampal formation across</span> <span>the goldfish pallium. Finally, aiding study of the teleostan everted telencephalon, we describe substantial</span> <span>molecular similarities between the goldfish and zebrafish neuronal taxonomies. Together, our atlas</span> <span>provides new insights into organization and evolution of vertebrate forebrains and may serve as a resource</span> <span>for the functional study underlying cognition in teleost fish.</span></p>
A telencephalon cell type atlas for goldfish reveals diversity in the evolution of spatial structure and cell types
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Supplementary data for: Identification of genes, cell types, and phenotypes under selective pressure across primate evolution
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Accelerated Cell Type Evolution in the Human Brain
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Single-cell genomics of the mouse olfactory cortex reveals contrasts with neocortex and ancestral signatures of cell type evolution
GEO Series GSE239477. Mus musculus. 72 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [Peromyscus]
GEO Series GSE237208. Peromyscus maniculatus. 8 samples. Type: Expression profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [ferret]
GEO Series GSE237203. Mustela putorius furo. 8 samples. Type: Expression profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [Tree_Shrew]
GEO Series GSE237213. Tupaia chinensis. 8 samples. Type: Expression profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [Marmoset]
GEO Series GSE237206. Callithrix jacchus. 8 samples. Type: Expression profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [human]
GEO Series GSE237204. Homo sapiens. 23 samples. Type: Expression profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [Pig]
GEO Series GSE237209. Sus scrofa domesticus. 11 samples. Type: Expression profiling by high throughput sequencing.
Profiling cellular diversity in sponges informs animal cell type and nervous system evolution
GEO Series GSE134912. Spongilla lacustris. 5 samples. Type: Expression profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [cow]
GEO Series GSE237202. Bos taurus. 10 samples. Type: Expression profiling by high throughput sequencing.
Genetic Characterization of the Cell Types of in Developing Feathers, and the Evolution of Feather Complexity
GEO Series GSE275984. Gallus gallus. 4 samples. Type: Expression profiling by high throughput sequencing.
Early metazoan cell type diversity and the evolution of multicellular gene regulation
GEO Series GSE111068. Mnemiopsis leidyi; Trichoplax adhaerens; Amphimedon queenslandica. 10 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [Opossum]
GEO Series GSE237207. Didelphis marsupialis. 11 samples. Type: Expression profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [Rhabdomys]
GEO Series GSE237210. Rhabdomys pumilio. 7 samples. Type: Expression profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [Lizard]
GEO Series GSE237205. Anolis sagrei. 6 samples. Type: Expression profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [Zebrafish]
GEO Series GSE237214. Danio rerio. 8 samples. Type: Expression profiling by high throughput sequencing.
Evolution of neuronal cell classes and types in the vertebrate retina [Sheep]
GEO Series GSE237211. Ovis aries. 8 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.