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75 results for “Citalopram”
Are you anxious yet? Investigating the effects of citalopram on the physiology and behavior of the rusty crayfish (Faxonius rusticus)
Selective serotonin reuptake inhibitors (SSRI) are a growing group of pollutants that are increasingly causing detrimental changes to aquatic ecosystems. Upon entering aquatic habitats, these chemicals affect both vertebrates and invertebrates by influencing fecundity, aggression, exploration, and mortality in non-target organisms. In crustaceans, more specifically in crayfish and lobsters, since serotonin (5-Hydroxytryptamine, 5-HT) has been linked to a suite of stress responses and agonistic behaviors, SSRIs have the potential to harm these organisms significantly. In this study, we aimed to quantify the effects of a twenty-one day exposure of citalopram on the behavior and physiology of the rusty crayfish (Faxonius rusticus). Crayfish were exposed to an environmentally relevant concentration (1 μg / L) of citalopram in their tank water for 21 days and perform physiological (oxygen consumption and stress analysis) and behavioral (flight initiation distance) assays. Changes in behavior (reaction distance), physiology (oxygen consumption), and neurotransmitter levels (stress) were used to quantify any effects due to citalopram exposure. We found that as the length of exposure increased, regardless of citalopram presence, the oxygen consumption rate decreased significantly. Females that were injected with supplemental 5-HT froze closer to a novel stimulus than males or individuals from other treatment groups. Females also took longer to explore the arena than males, regardless of treatment. The amount of 5-HT present in individuals increased with mass, but this was not observed in individuals exposed to an external stressor regardless of the presence or absence of citalopram in their system. Exposure to 1 μg / L of citalopram for 21 days did not significantly impact crayfish behavior, but behavior and oxygen consumption were impacted by sex and isolation length, respectively. While this concentration of citalopram did not alter behavior or physiology, further work is
Citalopram for Agitation in Alzheimer's Disease
ClinicalTrials.gov study NCT00898807. IPD Sharing: Not stated. Countries: 2. Publications: 3.
Brain Effects of Escitalopram and Citalopram Using fMRI
ClinicalTrials.gov study NCT00825825. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Citalopram to Enhance Cognition in HD
ClinicalTrials.gov study NCT00271596. IPD Sharing: Not stated. Countries: 1. Publications: 20.
Citalopram and the Risk of Serious Adverse Events
ClinicalTrials.gov study NCT07399795. IPD Sharing: NO. Countries: 1. Publications: 1.
Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics
ClinicalTrials.gov study NCT01657760. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Treatment for Bipolar Depression: Acute & Prophylactic Efficacy With Citalopram
ClinicalTrials.gov study NCT00562861. IPD Sharing: NO. Countries: 1. Publications: 1.
Citalopram for Cocaine Dependence
ClinicalTrials.gov study NCT01535573. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive Impairment
ClinicalTrials.gov study NCT01876823. IPD Sharing: Not stated. Countries: 1. Publications: 49.
DECIFER: Depression and Citalopram In First Episode Recovery
ClinicalTrials.gov study NCT01041274. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Comparison of Fluoxetine Versus Citalopram Therapy to Control Postmenopausal Vasomotor Syndrome
ClinicalTrials.gov study NCT05346445. IPD Sharing: NO. Countries: 1. Publications: 41.
Comparative Evaluation of Safety and Efficacy of Dapoxetine, Silodosin, and Citalopram in the Management of Premature Ejaculation
ClinicalTrials.gov study NCT07113145. IPD Sharing: NO. Countries: 1. Publications: 1.
Pipamperone/Citalopram (PipCit)Versus Citalopram in the Treatment of Major Depressive Disorder(MDD)
ClinicalTrials.gov study NCT00672659. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Trial of Citalopram for the Prevention of Depression
ClinicalTrials.gov study NCT00317746. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Citalopram in Treating Postmenopausal Women With Hot Flashes
ClinicalTrials.gov study NCT00363909. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Antidepressant Efficacy of Psychotherapy and Citalopram in Patients With Breast Cancer and Major Depression
ClinicalTrials.gov study NCT05063604. IPD Sharing: NO. Countries: 1. Publications: 8.
The Efficacy of Citalopram Treatment in Acute Stroke
ClinicalTrials.gov study NCT01937182. IPD Sharing: Not stated. Countries: 1. Publications: 6.
An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression
ClinicalTrials.gov study NCT00070694. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Pharmacokinetic Drug-drug Interaction Study Between RaltEgravir and CITALopram in Healthy Subjects (RECITAL).
ClinicalTrials.gov study NCT01978782. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Reboxetine and Citalopram as an Adjunct Treatment to Second Generation Antipsychotics in the Treatment of Negative Symptoms of Schizophrenia
ClinicalTrials.gov study NCT01300364. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
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