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Dataset results
55 results for “DCE”
DCE-MRI DRO Data (Daniel Barboriak)
<p>This is the digital reference object (DRO) data created to validate software build to analyse DCE-MRI with the General Kinetic Model (GKM) or extended GKM (eGKM) as well as software for evaluating T1 mapping using the variable flip angle (VFA) method.</p><p>The data has been produced for the Quantitative Imaging Biomarkers Alliance (QIBA) and was moved from the retired Quantitative Imaging Data Warehouse (QIDW).</p><p>It can be used to evaluate software packages for their conformance to the quantitative DCE-MRI Profile 2.0 soon to be release. </p>
FDG PET and DCE-MRI in Predicting Response to Treatment in Patients With Breast Cancer
ClinicalTrials.gov study NCT01931709. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Assessment of tumor treatment response using active contrast encoding (ACE)-MRI: comparison with conventional DCE-MRI
<p><strong>Purpose:</strong> To investigate the validity of contrast kinetic parameter estimates from Active Contrast Encoding (ACE)-MRI against those from conventional Dynamic Contrast-Enhanced (DCE)-MRI for evaluation of tumor treatment response in mouse tumor models.</p> <p><strong>Methods:</strong> The ACE-MRI method that incorporates measurement of <em>T<sub>1</sub></em> and <em>B<sub>1</sub></em> into the enhancement curve washout region, was implemented on a 7T MRI scanner to measure tracer kinetic model parameters of 4T1 and GL261 tumors with treatment using bevacizumab and 5FU. A portion of the same ACE-MRI data was used for conventional DCE-MRI data analysis with a separately measured pre-contrast <em>T<sub>1</sub></em> map. Tracer kinetic model parameters, such as <em>K<sup>trans</sup></em> (permeability area surface product) and <em>v<sub>e</sub></em> (extracellular space volume fraction), estimated from ACE-MRI were compared with those from DCE-MRI, in terms of correlation and Bland-Altman analyses. </p> <p><strong>Results:</strong> A three-fold increase of the median <em>K<sup>trans</sup></em> by treatment was observed in the flank 4T1 tumors by both ACE-MRI and DCE-MRI. In contrast, the brain tumors did not show a significant change by the treatment in either ACE-MRI or DCE-MRI. <em>K<sup>trans</sup></em> and <em>v<sub>e</sub></em> values of the tumors from ACE-MRI were strongly correlated with those from DCE-MRI methods with correlation coefficients of 0.92 and 0.78, respectively, for the median values of 17 tumors. The Bland-Altman plot analysis showed a mean difference of -0.01 /min for <em>K<sup>trans</sup></em> with the 95% limits of agreement of -0.12 /min to 0.09 /min, and -0.05 with -0.37 to 0.26 for <em>v<sub>e</sub></em>.</p> <p><strong>Conclusion:</strong> The tracer kinetic model parameters estimated from ACE-MRI and their changes by treatment closely matched those of DCE-MRI, which suggests that ACE-MRI can be used in place of conventional DCE-MRI for tumor progression monitoring and treatment response evaluation with a reduced scan time. <br> </p>
Evaluating Sunitinib Therapy in Renal Cell Carcinoma Using F-18 FDG PET/CT and DCE MRI
ClinicalTrials.gov study NCT00537056. IPD Sharing: YES. Countries: 1. Publications: 0.
DCE-CT of Thoracic Tumors as an Early Biomarker for Treatment Monitoring in Comparison With Morphologic Criteria
ClinicalTrials.gov study NCT04708483. IPD Sharing: NO. Countries: 1. Publications: 5.
The Use of Focused Ultrasound and DCE K-trans Imaging to Evaluate Permeability of the Blood-Brain Barrier
ClinicalTrials.gov study NCT04063514. IPD Sharing: Not stated. Countries: 1. Publications: 11.
DCE-MRI and DWI for Detection and Diagnosis of Breast Cancer
ClinicalTrials.gov study NCT02022579. IPD Sharing: YES. Countries: 1. Publications: 1.
DCE CT/MRI Scanning Study in Patients With Solid Tumours (AstraZeneca and Royal Marsden Hospital Imaging Study)
ClinicalTrials.gov study NCT00748891. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Assessment of tumor treatment response using active contrast encoding (ACE)-MRI: comparison with conventional DCE-MRI
Open the record for dataset details and reuse information.
Accurate DCE-MRI Measurement of Glioblastoma Using Point-of-care Portable Perfusion Phantom
ClinicalTrials.gov study NCT05140902. IPD Sharing: NO. Countries: 1. Publications: 0.
DSC-MRI With Ferumoxytol and DCE-MRI With Gadolinium in Imaging Vascular Properties in Younger Patients With Brain Tumors
ClinicalTrials.gov study NCT00978562. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Randomized Phase II Study of DCE-MRI-based Dose Escalation for Poor-prognosis and Neck Cancer
ClinicalTrials.gov study NCT02031250. IPD Sharing: Not stated. Countries: 1. Publications: 0.
DCE-MRI Using Dotarem® in Evaluation of Therapeutic Response to Sorafenib in Patients With Advanced Stage HCC
ClinicalTrials.gov study NCT01806740. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Suitability of DCE-MRI for Detection of Vascular Changes After VBT
ClinicalTrials.gov study NCT01991808. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Measure Response to Etanercept in Rheumatoid Arthritis
ClinicalTrials.gov study NCT00361634. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Integrative analysis of DCE-MRI and gene expression profiles in construction of a gene classifier for assessment of hypoxia-related risk of chemoradiotherapy failure in cervical cancer
GEO Series GSE72723. Homo sapiens. 302 samples. Type: Expression profiling by array.
Breast_Cancer_DCE-MRI_Data
<p>The dataset was specifically created for use in deep learning-aided segmentation tasks for breast cancer diagnosis. It comprises 100 cases obtained from Yunnan Cancer Hospital, each containing dynamic contrast-enhanced MRI (DCE-MRI) images with six phases, consisting of one pre-contrast image and five post-contrast images. Additionally, each case includes a breast tumor annotation (ground-truth image) and a whole breast annotation for accurate segmentation.</p>
Dynamic Contrast Enhanced MRI(DCE-MRI)of Bone Tumors
ClinicalTrials.gov study NCT00598741. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Patient Preference Study in Type-2 Diabetes Mellitus: Discrete Choice Experiment (DCE) to Support Novo Nordisk's Long-Acting Insulin
ClinicalTrials.gov study NCT06592950. IPD Sharing: YES. Countries: 1. Publications: 0.
Disposable Perfusion Phantom for Accurate DCE (Dynamic Contrast Enhanced)-MRI Measurement of Pancreatic Cancer Therapy Response
ClinicalTrials.gov study NCT04588025. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.