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339 results for “Diagnostic Test”
Evaluation of COVID-19 antigen rapid diagnostic tests for self-testing in Lesotho and Zambia - Zambia data
<p>Dataset with Zambia data belonging to the publication: Evaluation of COVID-19 antigen rapid diagnostic tests for self-testing in Lesotho and Zambia - Zambia data</p>
JRC COVID-19 In Vitro Diagnostic Devices and Test Methods Database
<p>SUMMARY</p> <p>The <em>JRC COVID-19 In Vitro Diagnostic Devices and Test Methods Database</em>, aimed to collect in a single place all publicly available information on performance of CE-marked <em>in vitro</em> diagnostic medical devices (IVDs) as well as <em>in house</em> laboratory-developed devices and related test methods for COVID-19, is here presented. The database, manually curated and regularly updated, has been developed as a follow-up to the Communication from the European Commission “Guidelines on <em>in vitro</em> diagnostic tests and their performance” of 15 April 2020 and is freely accessible at <a href="https://covid-19-diagnostics.jrc.ec.europa.eu/">https://covid-19-diagnostics.jrc.ec.europa.eu/</a>.</p>
Research Data for Comparative Evaluation of RT-PCR and Antigen-based Rapid Diagnostic Tests (Ag-RDTs) for SARS-CoV-2 Detection: Performance, Variant Specificity, and Clinical Implications
<p>This dataset represents laboratory findings for the comparative evaluation of the diagnostic performance of Ag-RDTs (Flourescence Immunoassay and Lateral Flow Immunoassay) with RT-PCR</p>
Transforming the UK's diagnostics agenda after COVID-19 and grand challenges – Future Blood Testing Landscape report - Prof Dimitris Grammatopoulos (University Hospitals Coventry & Warwickshire, University of Warwick)
<p>This video is the second talk from our two day Future Blood Testing: Challenges & Opportunities Event that took place on the 13/09/2022.</p> <p>Transforming the UK’s diagnostics agenda after COVID-19 and grand challenges – Future Blood Testing Landscape report - Prof Dimitris Grammatopoulos (University Hospitals Coventry & Warwickshire, University of Warwick)</p> <p>Bio: Dimitris Grammatopoulos, PhD, FRCPath, is Professor of Molecular Medicine at Warwick Medical School and Consultant in Clinical Biochemistry and Molecular Diagnostics at the University Hospitals of Coventry and Warwickshire, NHS Trust, United Kingdom. He also leads the Novel Biomarkers theme of the Institute of Precision Diagnostics and Translational Medicine, Pathology-UHCW NHS Trust. where he combines clinical expertise in diagnostic laboratory medicine with a research track-record in application of cutting edge multidiscipline methodologies in routine clinical diagnostics. He received academic and clinical training in Newcastle, Bristol, Johns Hopkins-Baltimore and Warwick. He has expertise in biochemical/molecular diagnosis of many endocrine and metabolic disorders. His translational research interest is focused on stress hormones and homeostatic adaptations of fetal development to maternal disease as well as development of novel -omics based biomarker approaches suitable for precision medicine and better characterisation of patient phenotype. He has experience around use of AI and ML for development and refinement of clinical and diagnostic pathways for complex chronic conditions that are considered as national priorities. Dimitris is the Lead in Diagnostics, Global Health Priorities in Health, University of Warwick.</p> <p>Further details on this event can be found at: https://futurebloodtesting.org/event/13-14-09-2022/</p> <p>This video is an output from the Future Blood Testing Network which is funded by EPSRC under Grant Number EP/W000652/1</p> <p>YouTube Link: https://youtu.be/HiOlRzJPR7Q</p>
The Politecnico di Torino rolling bearing test rig: description of the open-access data for vibration monitoring and diagnostics
<p>Accelerometric measurements from the rolling bearing test rig of the Dynamic and Identification Research Group (DIRG), Department of Mechanical and Aerospace Engineering, Politecnico di Torino.</p> <p>Goals:</p> <p> • Vibration Monitoring, Bearing Diagnostics, Damage detection, Damage localization, Damage classification, Damage assessment.</p> <p>Features:</p> <p> • high-speed spindle driving a hollow shaft supported by a couple of identical roller bearings B1 and B3. B1 is the bearing under analysis and features various damages.</p> <p> • two damage types (indentations on a roller and on the inner ring) and severities (0, 150, 250, 450 µm).</p> <p> • a central, larger roller bearing (B2) is loaded through a sledge generating a controlled radial force measured by a load cell.</p> <p> • lubrication is obtained by oil injection into the hollow shaft.</p> <p> • a K-type thermocouple is used to monitor the temperature (manually recorded).</p> <p> • two triaxial accelerometers are mounted on the supports of bearings B1 and B2.</p> <p>Dataset:</p> <p> • stationary acquisitions at different speed & load combinations (speed: 0, 100, 200, 300, 400, 500 Hz; load: 0, 1000, 1400, 1800 N).</p> <p> • endurance acquisitions of the bearing featuring the 450µm roller indentation. Monitoring of the damage evolution for about 230 hours under the same speed and load condition.</p> <p> </p> <p>The extended description of the dataset can be found in the attached pdf "Description and analysis of open access data" or in:</p> <p>A.P. Daga, A. Fasana, S. Marchesiello, L. Garibaldi, The Politecnico di Torino rolling bearing test rig: Description and analysis of open access data, Mechanical Systems and Signal Processing 120 (2019) 252–273. doi:10.1016/j.ymssp.2018.10.010.</p>
Fig. 4 in Giardia duodenalis in a clinically healthy population of captive zoo chimpanzees: Rapid antigen testing, diagnostic real-time PCR and faecal microbiota profiling
Fig. 4. | Faecal bacterial community profile of captive chimpanzees infected with Giardia duodenalis detected by rapid antigen test. (A) Relative abundance of colour coded bacterial phyla separated based on presence (+) or absence (‒) of Giardia using rapid antigen test (RAT). The sample identity is located at the bottom of the graph with two labels (C20, C3) shaded indicating samples that were found as Giardia positive by real-time PCR. (B) Alpha diversity based on observed OTU and Shannon's index plotted as box plot and evaluated using t-tests. (C) Principal coordinates analysis (PCoA) 2D plot using first two principal components from Bray-Curtis dissimilarity matrix at the genus taxonomic levels. The clustering between Giardia positive (RAT+) and negative (RAT-) samples was tested using ANOSIM. (D) Linear discriminant analysis effect size (LEfSe) used plot of significant factors discriminating G. duodenalis positive from negative sample. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 3 in Giardia duodenalis in a clinically healthy population of captive zoo chimpanzees: Rapid antigen testing, diagnostic real-time PCR and faecal microbiota profiling
Fig. 3. | Faecal bacterial community profile of captive chimpanzees infected with Giardia duodenalis as detected by rapid antigen test and real-time PCR combined. (A) Relative abundance of colour coded bacterial phyla separated based on presence (+) or absence (‒) of Giardia. The sample identity is located at the bottom of the graph. (B) Alpha diversity based on observed OTU and Shannon's index plotted as box plot and evaluated using t-tests. (C) Principal coordinates analysis (PCoA) 2D plot using first two principal components from Bray-Curtis dissimilarity matrix at the genus taxonomic levels. The clustering between Giardia positive (+) and negative (‒) samples was tested using ANOSIM. (D) Linear discriminant analysis effect size (LEfSe) used plot of significant factors discriminating G. duodenalis positive from negative sample. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 2 in Giardia duodenalis in a clinically healthy population of captive zoo chimpanzees: Rapid antigen testing, diagnostic real-time PCR and faecal microbiota profiling
Fig. 2. | Results of Giardia duodenalis rapid antigen test applied on faecal samples from chimpanzees. A positive result for the Giardia duodenalis rapid antigen test (RAT, Anigen Rapid Giardia AG Test Kit) is represented by the line in the 'T' position in the window along with the positive control line in the 'C' position.
Fig. 1 in Giardia duodenalis in a clinically healthy population of captive zoo chimpanzees: Rapid antigen testing, diagnostic real-time PCR and faecal microbiota profiling
Fig. 1. Captive chimpanzees and their enclosure in Sydney, Australia. (A) Main chimpanzee open air exhibit with multiple climbing structures. (B) View from the other direction showing entry to the indoor area at the end of the exhibit. (C) smaller exhibit with mesh covering and more climbing and sleeping structures. (D) Members of the chimpanzee troop at the Taronga Zoo.
Fig. 2 in Application of a universal parasite diagnostic test to biological specimens collected from animals
Fig. 2. Cluster dendrogram showing parasite species detected in mammalian hosts. Sequences detected in each specimen using nUPDx were clustered alongside parasite-derived reference sequences of known identity obtained from GenBank. These reference sequences are labelled on the dendrogram branch tips (where appropriate). A peripheral color-coded heat map ring indicates the host animal from which the parasite-derived sequence was detected. Gray branches and blocks on the heat map reflect the position of reference sequences within the tree. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Fig. 1 in Application of a universal parasite diagnostic test to biological specimens collected from animals
Fig. 1. Schematic describing the nested UPDx protocol employed in this study. This schematic provides a summary of the nested UPDx (nUPDx) protocol originally described by Flaherty et al. (Flaherty et al., 2021). Briefly, the DNA extract is subjected to a restriction digestion using the PstI restriction enzyme, and the digest product is subjected to PCR1 using primers 5'TTGATCCTGC- CAGTAGTCATATGC'3 (outer forward) and 5'GGTGTGTA- CAAAGGGCAGGGAC'3 (outer reverse). The resultant ~2 kb amplicon is digested using the restriction enzymes BamHI and BsoBI. The digest product is then subjected to PCR2 using internal primers 5'CCGGAGAGGGAGCCTGAGA'3 (inner forward) and 5'GAGCTGGAATTACCGCGG'3 (inner reverse) originally described by Flaherty et al. (Flaherty et al., 2018, 2021). The amplicon of PCR2 (~200 base pairs) is finally subjected to Illumina amplicon sequencing.
Fig. 3 in Application of a universal parasite diagnostic test to biological specimens collected from animals
Fig. 3. Cluster dendrogram showing parasite species detected in avian and reptilian hosts. Sequences detected in each specimen using nUPDx were clustered in this dendrogram alongside parasite-derived reference sequences of known identity obtained from GenBank. These reference sequences are labelled on the dendrogram branch tips (where appropriate). A peripheral color-coded heat map ring indicates the host animal from which the parasite-derived sequence was detected. Gray branches and blocks on the heat map reflect the position of reference sequences within the tree. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Figure 3 in Molecular test shows the color pattern is not so reliable in diagnostic of genus Dysphaea Selys (Odonata: Euphaeidae)
Figure 3. Phylogenetic reconstruction of 37 samples based on combined gene dataset (COI+16S+28S, 2394 bp). Bayesian posterior probabilities (left) and ML bootstrap value (right) are indicated at nodes. Among the central Vietnamese specimens of Dysphaea sp. the ID numbers in red color indicate those specimens with dark colour which were originally identified by us as D. basitincta. Those with ID in green indicate specimens originally identified by us as D. gloriosa. The blue ID refers to D. haomiao.
Figure 2 in Molecular test shows the color pattern is not so reliable in diagnostic of genus Dysphaea Selys (Odonata: Euphaeidae)
Figure 2. Photos of the right pair of wings of some male specimens showing the variations of wing color patterns. The wings of the syntype of D. basitincta (at MNHN, Paris) was kindly provided by Matti Hämäläinen.
Identifying diagnostic genetic markers for a cryptic invasive agricultural pest: a test case using the apple maggot fly, Rhagoletis pomonella (Diptera: Tephritidae)
Insect pests destroy ~15% of all USA crops, resulting in losses of $15 billion annually. Thus, developing cheap, quick and reliable methods for detecting harmful species is critical to curtail insect damage and lessen economic impact. The apple maggot fly, Rhagoletis pomonella (Diptera: Tephritidae), is a major invasive pest threatening the multibillion-dollar apple industry in the Pacific Northwest USA. The fly is also sympatric with a benign but morphologically similar and genetically closely related species, R. zephyria, which attacks non-commercial snowberry. Unambiguous species identification is essential due to a zero-infestation policy of apple maggot for fruit export. Mistaking R. zephyria for R. pomonella triggers unnecessary and costly quarantines, diverting valuable control resources. Here we develop and apply a relatively simple and cost-effective diagnostic approach using Illumina sequencing of double digest restriction-site associated DNA markers. We identified five informative single nucleotide polymorphisms (SNPs) and designed a diagnostic test based on agarose gel electrophoresis of restriction enzyme digested polymerase chain reaction amplification products (RFLPs) to distinguish fly species. We demonstrated the utility of this approach for immediate, one day species identification by scoring apple- and snowberry-infesting flies of known host plant identity, reared directly from 11 sites throughout Washington. However, if immediate diagnosis is not required, or hundreds to thousands of specimens must be assessed, then a direct Illumina-based sequencing strategy, similar to that used here for diagnostic SNP identification can be powerful and cost-effective. The genomic strategy we present is effective for R. pomonella and also transferable to many cryptic pests.
Improved estimation of the prevalence of bovine cysticercosis and the diagnostic test characteristics in the absence of a reference standard using Bayesian Latent Class models, the example of Jimma and Ambo Abattoirs, Ethiopia
<p>Bovine cysticercosis is an infection of cattle musculature with the cestode parasite of humans known as Taenia saginata. This bovine cysticercosis data was collected from two Ambattoirs in Ethiopia namely Ambo and Jimma. Dissection of the predilection site, Ag-ELISA, and meat inspection were the diagnostic methods employed. Cysticerci collected during dissection of the predilection site were also confirmed using multiplex PCR. </p>
Investigation of the diagnostic importance and accuracy of CT in the chest compared to the RT-PCR test for suspected COVID-19 patients in Jordan
<p>As the world continues to battle the COVID-19 pandemic, Jordan is no exception. In order to improve the accuracy of diagnosis, researchers in Jordan have conducted an investigation into the diagnostic importance and accuracy of CT in the chest compared to the RT-PCR test for suspected COVID-19 patients.</p>
Accuracy, acceptability, and feasibility of diagnostic tests for the screening of Strongyloides stercoralis in the field: the ESTRELLA study
<p>Raw data from the diagnostic study ESTRELLA. </p> <p>The primary objective of this study was to estimate the accuracy of five tests - a recombinant antigen- rapid diagnostic test (RDT); a crude antigen-based ELISA (Bordier ELISA); an ELISA based on two recombinant antigens (Strongy Detect ELISA); a modified Baermann method; an in-house real-time PCR for <em>Strongyloides stercoralis</em> infection. Secondary objectives were acceptability and feasibility of use in an endemic area.</p> <p>The study was carried out in remote villages of Ecuador</p>
Evaluation of COVID-19 antigen rapid diagnostic tests for self-testing in Lesotho and Zambia - Lesotho data
<p>Dataset with Lesotho data belonging to the publication: Evaluation of COVID-19 antigen rapid diagnostic tests for self-testing in Lesotho and Zambia</p>
Diagnostic Test Validity of Structural Vertebral Endplate Defects
ClinicalTrials.gov study NCT04808960. IPD Sharing: YES. Countries: 1. Publications: 9.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.