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5 results for “Dose-response curve”
CurveCurator: A recalibrated F-statistic to assess, classify, and explore significance of dose-response curves - Example Datasets
<p>CurveCurator is an open-source analysis platform for any dose-dependent data. It fits a classical 4-parameter equation to estimate effect potency, effect size, and the statistical significance of the observed response. 2D-thresholding efficiently reduces false positives in high-throughput experiments and separates relevant from irrelevant or insignificant hits in an automated and unbiased manner. An interactive dashboard allows users to quickly explore data locally.</p> <p><br> Here, we store example dose-dependent data, parameter files, and the corresponding CurveCurator pipeline outputs (v.0.2.0). Example data sets include Kinobeads Drug-binding data (1), CTRP Viability data sets (2), and deryptM Proteomics data sets (3). The F-value matrices for developing the CurveCurator tools are deposited as well.</p> <p>Original data sources:</p> <p>(1)<a href="https://doi.org:10.1126/science.aan4368"> https://doi.org:10.1126/science.aan4368</a></p> <p>(2) <a href="https://doi.org:10.1158/2159-8290.CD-15-0235">https://doi.org:10.1158/2159-8290.CD-15-0235</a></p> <p>(3) <a href="https://doi.org:10.1126/science.ade3925">https://doi.org:10.1126/science.ade3925</a></p> <p> </p>
Effect of a LAMA and a uLABA on the Methacholine Dose-response Curve
ClinicalTrials.gov study NCT02953041. IPD Sharing: YES. Countries: 1. Publications: 1.
A Randomised, Double Blind, Placebo Controlled, 4 Period, Incomplete Block, Crossover Study Assessing the Dose-response Curve of Fluticasone Propionate in an Antigen Challenge Chamber
ClinicalTrials.gov study NCT00848965. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dose-response Curves Between Propofol and Intraoperative Electroencephalographic Patterns
ClinicalTrials.gov study NCT04345926. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dose-Response Curve: Interventions to Prevent and Treat Radiodermatitis
ClinicalTrials.gov study NCT02249884. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.