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ShareScore release 0.9.0
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115 results for “Epidermal Keratinocytes”
RNAseq from normal human epidermal keratinocytes treated with C. acnes 6919 conditioned media and propionic acid
<p>Lipid synthesis is necessary for formation of epithelial barriers and homeostasis with external microbes. An analysis of the response of human keratinocytes to several different commensal bacteria on the skin revealed that <em>Cutibacterium acnes</em> induced a large increase in essential lipids including triglycerides, ceramides, cholesterol, and free fatty acids. A similar response occurred in mouse epidermis and in human skin affected with acne. Further analysis showed that this increase in lipids was mediated by short-chain fatty acids produced by <em>Cutibacterium acnes</em> and was dependent on increased expression of several lipid synthesis genes including glycerol3-phosphate-acyltransferase-3. Inhibition or RNA silencing of peroxisome proliferator–activated receptor–α (PPARα), but not PPARβ and PPARγ, blocked this response. The increase in keratinocyte lipid content improved innate barrier functions including antimicrobial activity, paracellular diffusion, and transepidermal water loss. These results reveal that metabolites from a common commensal bacterium have a previously unappreciated influence on the composition of epidermal lipids.</p>
RNAseq from normal human epidermal keratinocytes treated with C. acnes 6919 conditioned media and propionic acid
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Smad3 binding regions in human epidermal keratinocytes (HaCaT).
GEO Series GSE189303. Homo sapiens. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Xeno-free and Chemically Defined Human System for Culturing Human Epidermal Keratinocytes
GEO Series GSE109645. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
GRHL3 chromatin binding and the super-enhancer landscape are reorganized in different functional states of epidermal keratinocytes
GEO Series GSE86193. Homo sapiens. 56 samples. Type: Expression profiling by array.
GRHL3 binding and the enhancer landscape are reorganized during transitions between different functional states of epidermal keratinocytes
GEO Series GSE94471. Homo sapiens. 16 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.
Expression of proinflammatory genes in epidermal keratinocytes is regulated by the hydration status.
GEO Series GSE42653. Oryctolagus cuniculus. 30 samples. Type: Expression profiling by array.
Gene regulation in human epidermal keratinocytes by a Rho kinase inhibitor (Y-27632)
GEO Series GSE52515. Homo sapiens. 4 samples. Type: Expression profiling by array.
Tenascin-C expressing touch dome keratinocytes exhibit characteristics of all epidermal lineages [ATAC-seq]
GEO Series GSE228987. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Ablation of coactivator Med1 regulates bulge keratinocyte stem cells and accelerates epidermal regeneration after injury [skin wound]
GEO Series GSE50670. Mus musculus. 4 samples. Type: Expression profiling by array.
Tenascin-C expressing touch dome keratinocytes exhibit characteristics of all epidermal lineages [RNA-seq]
GEO Series GSE228988. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Human cathelicidin antimicrobial peptide LL37 effect on human neonatal epidermal keratinocytes (NHEKs).
GEO Series GSE49472. Homo sapiens. 12 samples. Type: Expression profiling by array.
Vitamin D receptor (VDR) regulates epidermal stem cells and cutanous wound healing [keratinocytes]
GEO Series GSE68729. Mus musculus. 2 samples. Type: Expression profiling by array.
Single-cell RNA sequencing of LPA induction in Normal Human Epidermal Keratinocytes (NHEKs)
GEO Series GSE167056. Homo sapiens. 144 samples. Type: Expression profiling by high throughput sequencing.
Reprogramming of epidermal keratinocytes by PITX1 transforms the cutaneous cellular landscape and promotes wound healing [scRNA-seq]
GEO Series GSE280067. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.
Epidermal Growth Factor Receptor inhibition triggers Type 1 Interferon signature in human keratinocytes
GEO Series GSE74407. Homo sapiens. 9 samples. Type: Expression profiling by array.
Interleukin-4 and interleukin-13 cytokines effect on epidermal keratinocytes
GEO Series GSE20706. Homo sapiens. 9 samples. Type: Expression profiling by array.
The effects of UVB and the organic osmolyte betaine on rat epidermal keratinocytes in an organotypic culture system
GEO Series GSE63004. Rattus norvegicus. 12 samples. Type: Expression profiling by array.
Microarray analysis of Human Epidermal Keratinocytes, neonatal (HEKn) exposed to solar-simulated visible and ultraviolet radiation with and without sunscreen protection.
GEO Series GSE103621. Homo sapiens. 84 samples. Type: Expression profiling by array.
Effect of Gsdma1and Gsdma3 epithelial knockout on gene expression of mouse dorsal skin keratinocytes after olive oil/acetonr treatment to induce epidermal barrier disruption
GEO Series GSE211369. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.