Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
54
datasets available to search
ShareScore release 0.9.0
Dataset results
54 results for “G × G interactions”
Intermolecular interactions in G protein-coupled receptor allosteric sites at the membrane interface from molecular dynamics simulations and quantum chemical calculations
<p>Allosteric modulators are called to be promising candidates in G protein-coupled receptor (GPCR) drug development by displaying target selectivity and fewer side effects. Among the allosteric sites known to date, extrahelical cavities represent an uncharacteristic binding location that raises many questions about the ligand interactions and stability; the binding site structure, and how all of these are affected by lipid molecules. In this work, we analyze the dynamics and interactions in the PAR2, C5aR1, and GCGR receptors unbound and bound to allosteric modulators at the receptor-lipid interface using molecular dynamics simulations in three lipid compositions. In addition, we performed quantum chemical calculations to further explore electrostatic interactions and the strength of atom pairwise contacts in the stabilization of the ligand-receptor complexes. We show that besides classical hydrogen bonds weak polar interactions such as O-HC, O-Br, and S-HC contacts and aromatic interactions contribute to the binding of allosteric modulators at the extrahelical sites in the middle of the membrane. The allosteric cavities are open and detectable in various membrane compositions but not always predicted as druggable. The availability of polar atoms for interactions in such cavities can be assessed by water molecules from the simulations. Although ligand-lipid interactions are weak, the lipid tails play a role in sizing and shaping the large part of the allosteric cavity. </p> <p>You will find the following files:</p> <ul> <li>Input files of the equilibration and production protocols of MD simulations (MD_simulations_inputs.zip)</li> <li>Input files and coordinate files of F-SAPT and NCIPLOT calculations (quantum_chemical_coordiates_inputs.zip)</li> </ul>
Optimization and improvement of output performance in G-band extended interaction klystron
<p>We optimized and improved the output performance of G-band Extended Interaction Klystron, including the optimized period, influence of gap voltage on the beam modulation, and optimized gap length as well as non-uniform gaps are analyzed, and these figures are the simulation results with .tif format.</p>
Data from: Gα and regulator of G-protein signaling (RGS) protein pairs maintain functional compatibility and conserved interaction interfaces throughout evolution despite frequent loss of RGS proteins in plants
Open the record for dataset details and reuse information.
F I G U R E 2 in Review of the chemical ecology of homoterpenes in arthropod-plant interactions
F I G U R E 2 Major ecological functions of DMNT and TMTT production by foliage and flowers in insect–plant interactions. Effect on plant fitness indicated by + and symbols for each interaction. Weight of arrows indicates the relative importance of each benefit to the plant in terms of reported cases. Dashed arrows indicate the potential non-beneficial effects of production by flowers on natural enemies and by foliage on pollinators.
F I G U R E 1 in Review of the chemical ecology of homoterpenes in arthropod-plant interactions
F I G U R E 1 Chemical structures of homoterpenes central to arthropod–plant interactions: n = 1, 4,8-dimethyl-1,3,7-nonatriene (DMNT); n = 2, 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT). R0, R00 = methyl
Supplementary material 3 from: Swenson SJ, Eichler L, Hörren T, Kolter A, Köthe S, Lehmann GUC, Meinel G, Mühlethaler R, Sorg M, Gemeinholzer B (2022) The potential of metabarcoding plant components of Malaise trap samples to enhance knowledge of plant-insect interactions. Metabarcoding and Metagenomics 6: e85213. https://doi.org/10.3897/mbmg.6.85213
Supplementary material 3 from: Swenson SJ, Eichler L, Hörren T, Kolter A, Köthe S, Lehmann GUC, Meinel G, Mühlethaler R, Sorg M, Gemeinholzer B (2022) The potential of metabarcoding plant components of Malaise trap samples to enhance knowledge of plant-insect interactions. Metabarcoding and Metagenomics 6: e85213. https://doi.org/10.3897/mbmg.6.85213
Fig. 1 a–g in Insemination by a kiss? Interactive 3D-microanatomy, biology and systematics of the mesopsammic cephalaspidean sea slug Pluscula cuica Marcus, 1953 from Brazil (Gastropoda: Euopisthobranchia: Philinoglossidae)
Fig. 1 a–g Three-dimensional reconstructions of Pluscula cuica miR croanatomy. a External aspect of body showing body openings, right view. a' Dorsal view of body with the dorsum above body cavity and head shown transparent, showing inner organ systems, arrowheads short nerves innervating Hancock's organs, asterisk anterior end of seminal groove. b Live specimen, ca. 2 mm total length, dorsal view. c Anterior left view of the central nervous system, pedal nerves omitted, double asterisk: large cell next to statocyst, d Posterior part of reproductive system, dorsolateral right view, white asterisk branching point of gonoduct to female glands and ampulla. e Copulatory apparatus, ventral view, anterior towards left. f Oblique right view of digestive system, salivary glands omitted, double white asterisks positions of salivary duct openings and small glandular field inside pharyngeal lumen. g Oblique dorsolateral right view of pericardial complex and surrounding organs. am ampulla, an anus, ao aorta, au auricle, bc bursa copulatrix, bcm buccal commissure, bg buccal ganglion, bs bursa stalk, cbc cerebro-buccal commissure, ccm cerebral commissure, cns central nervous system, cpg cerebropleural ganglion, cop copulatory apparatus, cr putative crop, dg digestive gland, dgl lumen of digestive gland, eg egg, es esophagus, fg1–fg4 nidamental glands (proximal to distal), fgl lumen of nidamental glands, gd gonoduct, gof female genital opening, gom male genital opening, ho Hancock's organs, it intestine, kd kidney, ln labiotentacular nerve, lng accessory labiotentacular ganglia, lpag left parietal ganglion, mo mouth opening, mu muscular tube, ncc nervus clypei-capitis, np nephropore, oc oocyte, of ovarial follicles, ogl oral glands, om odontophore musculature, orn oral nerve, osg osphradial ganglion, osp osphradium, ot oral tube, pc pericardium, pe penis, pg pedal ganglion, ph pharynx, pr prostate, r distal part of radula, r' origin of radula, rhga/rhgp anterior/posterior accessory rhinophoral ganglion, rhn rhinophoral nerve, rpd renopericardial duct, sg seminal groove, sgl salivary gland, shd shell dimple, shr shell remnant, st statocyst, subg+vg combined subintestinal and visceral ganglion, supg +rpag combined supraintestinal and right parietal ganglion, ve ventricle, vn visceral nerve, ygd duct of yellow gland, ygl yellow gland, ygp opening of yellow gland. Bars a, a', d, f 250 μm; c, e, g 100 μm. Interactive version of this figure is available in the supplementary online material.
Fig. 4 a–g in Insemination by a kiss? Interactive 3D-microanatomy, biology and systematics of the mesopsammic cephalaspidean sea slug Pluscula cuica Marcus, 1953 from Brazil (Gastropoda: Euopisthobranchia: Philinoglossidae)
Fig. 4 a–g Semithin histological cross-sections of anterior body half. dorsum, egl different types of epidermal glands, ft foot, gom male Dorsal side at top, in e: at right. a Level of mouth opening, showing genital opening, ho Hancock's organ, it intestine, ln labiotentacular lateral grooves. b Anterior part of CNS and copulatory organ. c Section nerve, lng accessory labiotentacular ganglion, mu strong muscular of CNS and copulatory organ posterior to b. d Detail of right Hanlining / muscular tube of copulatory organ, ogl oral gland, ot oral tube, cock's organ and its innervation. e Pharynx with muscular odontophore pe penis, ph pharynx, pn pedal nerves, pr prostate, rhga anterior and spread radula; asterisk patch of glandular cells. f Detail of pedal accessory rhinophoral ganglion, rhgp posterior accessory rhinophoral ganglion with statocyst and 'blister' cell (double asterisk). g Trunk-like ganglion, rhn rhinophoral nerve, sc statocyst, sgl salivary gland, vlg anterior end of intestine inside digestive gland lumen. bv blood vessel, visceral loop ganglia (sectioned at margins). Bars a 100 μm; b–e, g cbc cerebro-buccal connective, ccm cerebral commissure, cpg cerebro50 μm; f 25 μm pleuraganglion, dg digestive gland, dgl lumen of digestive gland, do
Supplementary material 1 from: Calderón-Rosete G, González-Barrios JA, Piña-Leyva C, Moreno-Sandoval HN, Lara-Lozano M, Rodríguez-Sosa L (2021) Transcriptional identification of genes light-interacting in the extraretinal photoreceptors of the crayfish Procambarus clarkii. ZooKeys 1072: 107-127. https://doi.org/10.3897/zookeys.1072.73075
Appendix S1, S2
Figure 1 from: Calderón-Rosete G, González-Barrios JA, Piña-Leyva C, Moreno-Sandoval HN, Lara-Lozano M, Rodríguez-Sosa L (2021) Transcriptional identification of genes light-interacting in the extraretinal photoreceptors of the crayfish Procambarus clarkii. ZooKeys 1072: 107-127. https://doi.org/10.3897/zookeys.1072.73075
Figure 1 Comparative alignments of opsins reported in the crayfish Procambarus clarkiiA long-wavelength-sensitive opsin (UniProtKB/Swiss-Prot: P35356.1; Hariyama et al. 1993); (GenBank: ALJ26467 1; Kingston and Cronin 2015); (Procl_ES_23_0; Manfrin et al. 2015) B short-wavelength-sensitive opsin (GenBank: ALJ26468.1; Kingston and Cronin 2015); (Procl_ES_11143_0; Manfrin et al. 2015)
Supplementary material 2 from: Swenson SJ, Eichler L, Hörren T, Kolter A, Köthe S, Lehmann GUC, Meinel G, Mühlethaler R, Sorg M, Gemeinholzer B (2022) The potential of metabarcoding plant components of Malaise trap samples to enhance knowledge of plant-insect interactions. Metabarcoding and Metagenomics 6: e85213. https://doi.org/10.3897/mbmg.6.85213
Table S2
Supplementary material 1 from: Swenson SJ, Eichler L, Hörren T, Kolter A, Köthe S, Lehmann GUC, Meinel G, Mühlethaler R, Sorg M, Gemeinholzer B (2022) The potential of metabarcoding plant components of Malaise trap samples to enhance knowledge of plant-insect interactions. Metabarcoding and Metagenomics 6: e85213. https://doi.org/10.3897/mbmg.6.85213
Table S1
Figure 2 from: Becerra-Chiron IM, Moya-Raygoza G, Muñoz-Urias A (2017) Host-Dryinidae (Hymenoptera) interactions on edge grasses of maize agroecosystem throughout winter in Mexico. Journal of Hymenoptera Research 57: 155-166. https://doi.org/10.3897/jhr.57.12990
Figure 2 - Quantitative food web of parasitoid-host interaction found on the edges of maize agroecosystem in the winter seasons of 2014 and 2015. Top names are the parasitoid species and bottom names are the host species.
Figure 1 from: Becerra-Chiron IM, Moya-Raygoza G, Muñoz-Urias A (2017) Host-Dryinidae (Hymenoptera) interactions on edge grasses of maize agroecosystem throughout winter in Mexico. Journal of Hymenoptera Research 57: 155-166. https://doi.org/10.3897/jhr.57.12990
Figure 1 - Total of parasitoid-host interactions found on the edges of maize agroecosystem in the winter seasons of 2014 and 2015. Name in parenthesis show the name of the host tribe.
Figure 9 from: Rousse P, Broad G, van Noort S (2016) Review of the genus Genaemirum Heinrich (Ichneumonidae, Ichneumoninae) with interactive identification keys to species. ZooKeys 635: 77-105. https://doi.org/10.3897/zookeys.636.10216
Figure 9 - Genaemirum varianum (Tosquinet). Holotype male. A habitus lateral view (inset: data labels) B head, mesosoma, dorsal view C head anterior view D head, mesosoma anterior-lateral view E metasomal tergites 1-4 dorsal view F propodeum, dorsal view.
Figure 10 from: Rousse P, Broad G, van Noort S (2016) Review of the genus Genaemirum Heinrich (Ichneumonidae, Ichneumoninae) with interactive identification keys to species. ZooKeys 635: 77-105. https://doi.org/10.3897/zookeys.636.10216
Figure 10 - Genaemirum vulcanicola Heinrich. Holotype female. A habitus lateral view (inset: data labels) B head, mesosoma, dorsal view C head anterior view D head, mesosoma anterior-lateral view E metasomal tergites 1-4 dorsal view F propodeum, dorsal view.
Figure 7 from: Rousse P, Broad G, van Noort S (2016) Review of the genus Genaemirum Heinrich (Ichneumonidae, Ichneumoninae) with interactive identification keys to species. ZooKeys 635: 77-105. https://doi.org/10.3897/zookeys.636.10216
Figure 7 - Genaemirum rhinoceros Heinrich. Holotype female. A habitus lateral view (inset: data labels) B head, mesosoma, dorsal view C head anterior view D head, pronotum anterior-lateral view E metasomal tergites 1-2 dorsal view F propodeum, dorsal view.
Figure 8 from: Rousse P, Broad G, van Noort S (2016) Review of the genus Genaemirum Heinrich (Ichneumonidae, Ichneumoninae) with interactive identification keys to species. ZooKeys 635: 77-105. https://doi.org/10.3897/zookeys.636.10216
Figure 8 - Genaemirum varianum (Tosquinet). Paratype female. A habitus lateral view (inset: data labels) B head, mesosoma, dorsal view C head anterior view D head, pronotum anterior-lateral view E fore-tibial armature F propodeum, dorsal view.
Figure 6 from: Rousse P, Broad G, van Noort S (2016) Review of the genus Genaemirum Heinrich (Ichneumonidae, Ichneumoninae) with interactive identification keys to species. ZooKeys 635: 77-105. https://doi.org/10.3897/zookeys.636.10216
Figure 6 - Genaemirum mesoleucum Heinrich. Holotype female. A habitus lateral view (inset: data labels) B head, mesosoma, dorsal view C head anterior view D head, pronotum lateral view E metasomal tergites 1-4 dorsal view F propodeum, dorsal view.
Figure 3 from: Rousse P, Broad G, van Noort S (2016) Review of the genus Genaemirum Heinrich (Ichneumonidae, Ichneumoninae) with interactive identification keys to species. ZooKeys 635: 77-105. https://doi.org/10.3897/zookeys.636.10216
Figure 3 - Genaemirum phacochoerus sp. n. Holotype female. A habitus lateral view (inset: data labels) B head, mesosoma, dorsal view C head anterior view D head, mesosoma anterior-lateral view E metasomal tergites 1-4 dorsal view F propodeum, dorsal view.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.