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9 results for “GO terms”
Raw and processed GO term data to support running GCEA analyses using ensemble-based nulls, as described in the manuscript, 'Overcoming bias in gene category enrichment analyses of brain-wide transcriptomic data'.
<p>Data to support a toolbox for performing gene category enrichment analyses, including against ensembles of null phenotypes.</p> <p>Descriptions of how these data files can be used for this purpose are in the documentation for the toolbox, at https://github.com/benfulcher/GCEA_FalsePositives</p>
GO Term annotations for five plants species from Phytozome by FANTASIA
<p>This is the GO term annotation made with FANTASIA for five species (Arabidopsis thaliana, Oryza sativa, Zea mays, Populus trichocarpa, and Solanum lycopersicum) from the Phytozome 13 datasets as proof of concept for this tool.</p>
Diaphorina citri new genome annotations and GO terms (2021)
<p>Additional genome annotations for the <em>Diaphorina citri</em> genome (Diaci_v3) including: TEs, intergenic regions and putative promotors, also additional gene ontology terms annotated using EGGnog. </p>
A Study to Find Out How Safe Long-term Treatment With Fezolinetant is in Women With Hot Flashes Going Through Menopause
ClinicalTrials.gov study NCT04003389. IPD Sharing: YES. Countries: 8. Publications: 2.
GO and KEGG terms analysis files between TLR2-4 and WT cells
<p><em><span>Staphylococcus aureus</span></em><span> infections pose a potential threat to livestock production and public health. A novel strategy is needed to control <em>S. aureus</em> infection due to its adaptive evolution to antibiotics. Autophagy plays a key role in degrading bacteria for innate immune cells.</span> <span>In order to promote <em>S. aureus</em> clearance via TLR induced autophagy pathway, the domain fusion TLR2-4 with the extracellular domain of TLR2, specific recognizing <em>S. aureus</em>, and transmembrane and intracellular domains of TLR4 is assembled, then the goats expressing TLR2-4 is generated. TLR2-4 substantially augments the removal of <em>S. aureus</em> within macrophages by elevating autophagy level. Phosphorylated JNK/ERK1/2 promote LC3-puncta in TLR2-4 macrophages during <em>S. aureus</em>-induced autophagy via MyD88-mediated the TAK1 signaling cascade. Meantime, the TRIF-dependent TBK1-TFEB-OPTN signaling is involved in TLR2-4-triggered autophagy after <em>S. aureus</em> challenge. Moreover, the transcript of <em>ATG5 </em>and <em>ATG12 </em>is significantly increased via cAMP-PKA-NF-</span><span>k</span><span>B signaling, which facilitates <em>S. aureus</em>-induced autophagy in TLR2-4 macrophages. Overall, the novel receptor TLR2-4 enhances the autophagy-dependent clearance of <em>S. aureus</em> in macrophages via TAK1/TBK1-JNK/ERK, TBK1-TFEB-OPTN and cAMP-PKA-NF-</span><span>k</span><span>B-ATGs signaling pathways, which provide an alternative </span><span>approach to resistant against <em>S. aureus</em> infection.</span></p>
GO and KEGG terms analysis files between TLR2-4 and WT cells
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Biclusters and their enriched go terms
<p>Biclusters and enriched go terms.</p>
GO-term results Epichloe
<p>Significantly enriched GO-terms (<em>p</em> < 0.01) for all sweeps regions and grouped by genomic compartment from the study: "<strong>Contrasting genome-wide signatures of selection in two closely related </strong><em>Epichloe </em><strong>plant pathogen species"</strong></p>
A Study to Assess Long-term Safety of Fezolinetant Given to Japanese Women Going Through Menopause
ClinicalTrials.gov study NCT06206421. IPD Sharing: YES. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.