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Dataset results
53 results for “IAPS”
PsPM-HRM5: SCR, ECG and respiration measurements in response to positive/negative IAPS pictures, and neutral/aversive sounds
<p>This dataset includes skin conductance response (SCR), electrocardiogram (ECG) and respiration measurements for each of 19 healthy unmedicated participants (8 males and 11 females aged 26.1 +/- 5.4 years) in response to 65 dB and 85 dB sounds as well as the 60 most arousing negative and the 60 most arousing positive (excluding explicit nude) IAPS pictures, presented for 1 s each. ITI was between 4-16 s.</p>
PsPM-trSP1: SCR, and heart beat measurement in response to aversive/neutral IAPS pictures while subjected to auditory distractors
<p>This dataset includes skin conductance response (SCR) and pulse time stamp (HB) measurements for each of 60 healthy unmedicated participants (30 males and 30 females aged 23.7 +/- 4.8 years) in response to the 45 most arousing negative, and 45 least arousing neutral IAPS pictures, each presented for 1 s each, while listening to regular or random distractor sounds, as described in Bach et al. (2015). ITI was selected randomly on each trial from 7.65 s, 9 s, or 10.35 s. The experiment was preceded by a 2-minute resting period and divided into 3 blocks, separated by resting periods. Each resting period begins and ends with an event marker in the psychophysiological recordings.</p>
PsPM-RRM3: SCR, ECG and respiration measurement in response to aversive/arousing IAPS pictures, and neutral/aversive sounds
<p>This dataset includes skin conductance response (SCR), electrocardiogram (ECG) and respiration measurements for each of 20 healthy unmedicated participants (10 males and 10 females aged 25.3 +/- 5.1 years; male/female numbers were misprinted in Bach et al. 2016) in response to negatively and positively arousing IAPS pictures and neutral (65 dB) and aversive (85 dB) white noise sounds. All stimuli had 1 s duration. ITI was selected randomly on each trial from 40 s, 45 s or 50 s.</p>
PsPM-trSP3: SCR measurement in response to aversive/arousing/neutral IAPS pictures while subjected to auditory distractors
<p>This dataset includes skin conductance response (SCR) measurements for each of 40 healthy unmedicated participants (20 males and 20 females aged 21.9 +/- 3.8 years) in response to the 16 most arousing negative, and most arousing positive (excluding explicit nude) and 16 least arousing neutral IAPS pictures, presented for 1 s each in 1 block, while listening to regular or random distractor sounds, as described in Bach et al. (2015). ITI was 4 s, plus a variable delay of around 0.4 s for image loading.</p>
PsPM-trSP2: SCR measurement in response to neutral IAPS pictures while subjected to auditory distractors
<p>This dataset includes skin conductance response (SCR) measurements for each of 61 healthy unmedicated participants (30 males and 31 females, misprinted in Bach et al. 2015, aged 25.7 +/- 4.5 years) in response to the 45 least arousing neutral IAPS pictures, presented for 1 s each in 3 blocks, while listening to regular or random distractor sounds, as described in Bach et al. (2015). Inter stimulus interval was randomly determined as 7.65 s, 9 s, or 10.35 s. Each recording starts with a 2-minute baseline interval.</p>
PsPM-HRM_IAPS: SCR, ECG and respiration measurement in response to aversive/arousing/neutral IAPS pictures
<p>This dataset includes skin conductance response (SCR), electrocardiogram (ECG) and respiration measurements for each of 23 healthy unmedicated participants (10 males and 13 females aged 22.6 +/- 3.9 years, age is misprinted in Paulus et al. 2016) in response to the 16 most arousing negative, the 16 most arousing positive (excluding explicit nude), and the 16 least arousing neutral IAPS pictures, presented for 1 s each. ITI was selected randomly on each trial from 43 s, 45 s or 47 s.</p>
RDK-IAPS paradigm EEG, target vs distractor
Open the record for dataset details and reuse information.
Towards Dynamical Annual To Decadal Climate Prediction Using the IAP-CAS Model
<p>We execute a set of Annual to Decadal (A2D) hindcast experiments using the IAP-CAS model (FGOALS-f2), which integrates 129 months of each prediction initialized from 1981 to 2015 annually, and evaluate the results of this experiment. The IAP-CAS model output associated with this work is stored here.</p>
IAP in Crohn's disease
<p class="MsoNormal"><span>The study examines the effect of cellular inhibitor of apoptosis protein (cIAP) inhibition on monocyte and PBMC cytokine production and cell death in healthy and Crohn's disease subjects. PBMCs from healthy controls were exposed to 4h of doses ranging from 0.1 to 1.0 micromolar of SMAC mimetics (SM) LCL161 and BV6 and co-incubated with LPS. SM consistently and dose-dependently reduced mRNA production of TNF-a, IL6 and IL-1b as determined by standard qPCR. A similar effect was seen on protein expression of TNF-a as determined by ELISA. To determine if this reduction in cytokine production was secondary to cell death, standard flow cytometry using ANX5 antibodies and nuclear dye 7AAD was performed. PBMCs were exposed from 4-16 hours to SM and/or LPS. Overall, neither of the stimulations LPS, SM or combined LPS/SM induced cell death. To determine if the effect was specific to LPS-induced signaling, PBMCs from healthy controls and from patients with inactive Crohn's disease were exposed to LPS, MDP and entero-adhesive <em>E. coli</em>. Only LPS-induced TNF expression was inhibited by BV6. This effect was seen in both healthy controls and Crohn's patients. Since monocytes are a major source of TNF-a in the intestine and important for intestinal inflammation and treatment responses in Crohn's disease we went on to examine how TNF-a production was affected in primary human monocytes. SMs reduced LPS-induced TNF-a mRNA expression in monocytes as determined by routine qPCR. We screened for different known modulators of IAP signaling (infliximab, zVAD, GSK 872, Nec1s, and NSA) by exposing PBMCs to these inhibitors and/or LPS and SMs. Only the RIPK1 inhibitor Nec1s was able to reverse SM-inhibition of LPS-induced TNF mRNA expression. Further, by standard Western blotting, we found that SM decreased the p-p65/total p65 ratio suggesting downstream inhibition of NFkB. To test if RIPK1 is involved in LPS-mediated TNF-a production we tested TNF-a mRNA expression by routine qPCR in the monocyte cell line THP1. Experiments were done on THP1 wild-type cells and THP1 RIPK1 K/O cells. RIPK1 K/O increased LPS-mediated TNF-a expression. In conclusion, SM can inhibit TNF-a, IL-1b and IL-6 expression without induction of cell death. The effect might in part be mediated RIPK1.</span></p> <p class="MsoNormal"><span>The data set provides the qPCR, ELISA and flow cytometry data in the order mentioned above. Each experiment is labelled according to cells used, exposure to inhibitors, length of stimulation where appropriate. qPCR data are normalized to LPS-only exposed cells, protein levels as pg/mL, flow cytometry data are shown as % cells, and Western blot quantification as pixels (ImageJ). </span></p>
Evaluating Effectiveness of Elevated Intra-abdominal Pressure (IAP) by PressureDOT
ClinicalTrials.gov study NCT06709924. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
IAP in Crohn's disease
Open the record for dataset details and reuse information.
Input data of the IAP-CAS S2S system
<div> <div> <div> <p>This is the boundary conditions and input data for the IAP-CAS S2S system.</p> </div> </div> </div>
Varenicline and Alcohol in Inpatient Addictions Program (IAP)
ClinicalTrials.gov study NCT01169610. IPD Sharing: Not stated. Countries: 1. Publications: 0.
DNA microarray analysis using jejunum from wild-type or IAP knockout (Akp3-/-) mice administered with IIAEK (Ile-Ile-Ala-Glu-Lys)
GEO Series GSE290759. Mus musculus. 12 samples. Type: Expression profiling by array.
IAP proteins control polarization and immune-metabolism in committed macrophages
GEO Series GSE106451. Mus musculus. 4 samples. Type: Expression profiling by array.
Uncovering the rewired IAP-JAK regulatory axis as an immune-dependent vulnerability of LKB1-mutant lung cancer
GEO Series GSE273406. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Whole-genome IAP methylation data for mouse sperm and tail DNA.
GEO Series GSE102989. Mus musculus. 2 samples. Type: Methylation profiling by high throughput sequencing.
Antagonism of IAPs enhances CAR T cell efficacy
GEO Series GSE124140. Homo sapiens; Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
RNA m6A modification mediated by METTL3 is important for IAP heterochromatin integrity in mESCs (WGBS)
GEO Series GSE126239. Mus musculus. 8 samples. Type: Methylation profiling by high throughput sequencing.
Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm
GEO Series GSE139128. Mus musculus. 104 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.