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15 results for “Information Security”
Vector sequences in early WIV SRA sequencing data of SARS-CoV-2 inform on a potential large-scale security breach at the beginning of the COVID-19 pandemic
<p>DESCRIPTION</p> <p>Sequences identified as Influenza A virus, Spodoptera frugiperda rhabdovirus and Nipah henipavirus have been previously identified within the early HiSeq 1000 and HiSeq 3000 sequencing data of SARS-CoV-2, SRR11092059,SRR11092060,SRR11092061 and SRR11092062, and were being used to support the hypothesis that a "simultaneous outbreak of multiple zoonotic viruses" have happened in the Huanan Seafood market. https://doi.org/10.31219/osf.io/s4td6</p> <p>However, a closer examination of these sequences revealed that they were not sequences of actual wild viruses, but were in stead fragments left behind from PCR products and cloning vectors harboring both cDNA clones and infectious clones of such viruses, with evidence of viral sequences being joined directly to DNA sequences of vector and non-human origin within the same short reads.</p> <p>Here are the vector sequences and PCR product-like sequences recovered from the earliest WIV SRA sequencing data of Human SARS-CoV-2 from dataset SRR11092059,SRR11092060,SRR11092061,SRR11092062.</p> <p>Sequences associated with Vectors and PCR products from 3 distinct viral species have been obtained: The 3'-end of a Nipah Henipahvirus with fusion to a Hepatitis D virus Ribozyme, a T7 terminator and a Tetracycline resistance gene, The 5'-end of the same Nipah Henipahvirus with fusion to sequences found in diverse vectors, A complete vector genome encoding the HA gene of Influenza A virus subtype H7N9 under a CMV promoter and a bgH polyA terminator, and 221 Contiguous sequences corresponding to the Spodoptera frugiperda rhabdovirus reference genome fused to sequences that were homologous to multiple Plastid sequences and Notably Mitochondrial sequences of Rodents.</p> <p>As sequences corresponding to a rescued infectious clone of a BSL-4 organism (Nipah Henipahvirus) were found in sample sequences that supposedy represents patient samples that were obtained from Hospital ICU and sequenced in a pathogen diagnosis laboratory (which is separate from the Virology Research laboratory which is implied by the context of an Infectious Clone of such an organism, evident by the 3'-HDV ribozyme and T7 terminator fused directly to the 3'-terminus of the Nipah Henipahvirus reads), The discovery of artifact-containing sequences of at least 3 different pathogen species that are phylogenetically and methodologically distinct from each other in samples that were supposedly submitted by a laboratory that is Separate from the virological research laboratories that could have hosted such clone sequences imply extensive crosstalk and cross-contamination between the various laboratories within the Wuhan Institute of Virology, which includes at least one BSL-4 laboratory with evidence of containment breach of a BSL-4 organism and it's subsequent introduction into RNA-seq samples that were processed by a laboratory of distinct and separate purposes than the basic virological research evidenced by the Infectious Clone of the Hipah Henipahvirus.</p> <p>Such a discovery therefore likely imply a major security breach happening within the Wuhan institute of Virology at the time when the first sequences of SARS-CoV-2 was sampled and sequenced, which have important implications on the origins of the SARS-CoV-2 virus itself.</p> <p>METHODS</p> <p>The metagenomic sequencing datasets, SRR11092059,SRR11092060,SRR11092061 and SRR11092062 were first analyzed using the NCBI phylogenetic analysis tool, which identified viral sequences that is not related to SARS-CoV-2 itself. These include Influenza A virus (IAV, subtype H7N9), Spodoptera frugiperda rhabdovirus and Nipah Henipahvirus.</p> <p>The datasets were then subjected to BLAST search using MEGABLAST against the reference sequences of such viruses to verify the existence of the viral sequences and determine the exact sybtype of such viruses and the closest sequences on GenBank that corresponds to the reads. There seuqences are MH926031.1 for the Spodoptera frugiperda rhabdovirus, KY199425.1 for the Influenza A virus and AY988601.1 for the Nipah Henipahvirus.</p> <p>A second round BLAST analysis with these identified sequences were then performed, which unexpectedly revealed numerous reads corresponding to Cloning vectors and non-human Mitochondrial and Plastid sequences being fused directly to the sequences of the identified viral species. Reads were then downloaded and subjected to assembly using the CAP3 sequence assembly program and the EGASSEMBLER tool. Contig sequences were then queried against the NCBI nr/nt database which unanimously identified the original sample sequences as viral sequences inserted into cloning vectors.</p> <p>The complete sequence of the Influenza A virus Haemagluttinin (HA) gene clone was obtained from SRR11092061,SRR11092062 using multiple rounds of BLAST search and sequence assembly expansion on the existing vector-virus junction contigs, and a partial sequence corresponding the 3'-end of Nipah Henipahvirus AY988601.1 fused to a 3'-HDV ribozyme, T7 terminator and a Tet resistance gene was obtained from SRR11092059. In addition, 221 Contig sequences corresponding to the Rhabdovirus MH926031.1 fused to Chloroplast sequence MN524635.1 and Rodent Mitochondrial sequence MT241668.1 have been recovered from SRR11092061.</p> <p>We then performed a BLAST search using the identified vector sequences on SRR11092059,SRR11092060,SRR11092061 and SRR11092062, which confirms the existence of these two vetor sequences in all 4 datasets.</p>
Designing a Training Journey for Privacy and Information Security Practitioners in the Federal Public Administration
<p> Context : The Ministry of Management and Innovation in Public Services (MGI) leads the formulation and coordination of the Digital Government Strategy (EGD). DEPSI, under the Secretariat of Digital Government (SGD), is responsible for the Privacy and Information Security Program (PPSI), which aims at data privacy, compliance, and institutional resilience. Problem: The culture of privacy and information security in the Federal Public Administration faces development challenges. Despite the PPSI, there is a lack of awareness initiatives, training, a clear strategy, best practices, and performance indicators. Proposed Solution: The proposal aims to develop a training journey for Practitioners working in roles related to privacy and information security, with the goal of identifying and promoting the best practices, skills, and competencies required for these roles. IS Theory: This study aligns with Organizational Information Processing Theory, providing mechanisms to help organizations adapt to regulatory uncertainties in privacy and security. Method: We employed a mixed approach, combining document analysis, a literature review, and a survey. Guidelines and standards were analyzed to map competencies and responsibilities, while the survey gathered practitioners' perceptions of the proposed training journey. Summary of Results: We identified the key profiles and their corresponding responsibilities, and proposed a personalized training journey. Survey results indicated that the journey meets Practitioners’ expectations, being well-evaluated in terms of criteria and assigned weights. Contributions and Impact in IS: This work contributes by presenting a proposal for a Training Journey to assess the knowledge of Federal Public Administration employees and guide them on the best paths for professional development. </p>
Q3. To what extent that information from the Internet should be censored?-Computer-Mediated Security Threats into the Web 2.0 Society
<p>Following this distribution, we can observe that a large part of the subjects (44,7%) consider that the information from the internet should be moderately censored (against various risks and social dangerous). Beside them, 26.6% evaluate that this process should be wider, and 28.7% think it should be lower. These two almost equal groups consolidate the central trend, and reflect a quite important worry concerning this perspective. The Internet has begun as an almost totally free of control medium, a quasi-anarchic structure, a symbol for the freedom of expression for any users. In time, it has become more and more accessible, and a large amount of information has become available inside the Info-sphere. Now, due to some negative consequences, it looks like starting to censure some information is not a prohibitive idea anymore, but rather a desirable one. We want to stress on the fact that the sample was formed by regular users that are not experts in security issues and thus, the recognizing of the importance of having a moderate censuring onto the Internet is a very significant conclusion. With an indirect connection to the previous item, the next question has directly approached a special topic related to the user’s knowledge about the dark web and/or deep web. These represent a quite particularly topic among the Internet users, and represent an area where the IP tracking is difficult or not-possible. Into this kind of sites and applications any user can remain anonymous, no matter what he/she does, posts or accesses.</p>
[DATA_SCIENCE] Interviews: The Secure Anonymised Information Linkage Databank (SAIL)
<p>This is a set of interview transcripts executed by Niccolò Tempini between September 2015 and October 2016, as part of the ERC project "The Epistemology of Data-Intensive Science", and in the context of a case study of SAIL. Please read the "Notes on transcript editing" document for further information.</p> <p>Two papers that specifically make use of these interviews have been published as of 2018:</p> <ul> <li>Tempini, N., Leonelli, S., 2018. Concealment and discovery: The role of information security in biomedical data re-use. Soc Stud Sci 48, 663–690. <a href="https://doi.org/10.1177/0306312718804875">https://doi.org/10.1177/0306312718804875</a></li> <li>Tempini, N., 2016. Science Through the “Golden Security Triangle”: Information Security and Data Journeys in Data-intensive Biomedicine, in: Proceedings of the 37th International Conference on Information Systems (ICIS 2016). <a href="https://aisel.aisnet.org/icis2016/ISHealthcare/Presentations/20/">https://aisel.aisnet.org/icis2016/ISHealthcare/Presentations/20/</a></li> </ul> <p>The transcripts document SAIL researchers' experience of infrastructure development and data curation and re-use practices. Researchers have consented to have these transcripts made available as Open Data. Other interviewees did not give consent, so those transcripts are held securely by the research team in Exeter.<br> You also find the information sheet provided to interviewees, which gives you the context for this project. Further information and related publications can be found at www.datastudies.eu.</p>
Information security education: a thematic trend analysis
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InfoSecSoS - Ontology for Information Security Management in Systems-of-Systems
<p>The intense transformations that have taken place in society in this decade have made information systems (IS) more complex. Such complexity relates to a category of systems defined as systems-of-systems (SoS). Although SoS offers benefits to organizations, the difficulty of Information Technology (IT) managers in dealing with information security in these systems can leave them vulnerable to threats and impacts caused by cyber attacks. Researchers consider that ontologies can be used as a solution to this problem because they define knowledge structures and promote a shared understanding of a domain, task or application. The objective of this research is to develop a domain ontology to support IT managers in decision making on information security issues in the context of SoS. For this, a systematic mapping study (SMS) was conducted to identify which information security technologies have been applied in the context of SoS. A survey research was carried out to analyze how these aspects have been perceived by specialists who work professionally in the industry or have research projects applied in real scenarios within the scope of these systems. Methodology 101 was also applied for the development of an information security domain ontology in SoS. Finally, the ontology evaluation was performed through a focus group with specialists, the ontology refinement and the feasibility study. The ontology aims to ensure the management of security knowledge in SoS and its shared understanding so that stakeholders, IT managers and their teams can avoid risks, vulnerabilities and threats in SoS. Its contribution is the standardization of concepts, terms and definitions, as well as the ease of sharing information to make more explicit assumptions and assist in the analysis of knowledge and domain relationships.</p>
Checking Secure Information Flow of CoCoME using UPPAAL
<p>Model of the CoCoME case study for the UPPAAL model checker. Also includes auto-generated verification models for checking the information flow security of CoCoME, and the corresponding verification properties.</p>
PROBLEMS OF PROFESSIONAL COMPETENCE DEVELOPMENT OF INFORMATION SECURITY OF FUTURE MILITARY SPECIALISTS AND ITS CURRENT STATE
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MEUSec - Method for Enhancing User Experience and Information Security
<p><strong>Detailed process model of the MEUSec method:</strong></p> <p><em><strong>Third Version: ... tbd ...</strong></em></p> <p><em><strong>Second Version: A case study of the MEUSec method to enhance user experience and information security of digital identity wallets. 2025. Journal of Interactive Media (i-com). <a href="https://doi.org/10.1515/icom-2024-0057" target="_blank" rel="noopener">https://doi.org/10.1515/icom-2024-0057</a> </strong></em></p> <p><em><strong>First Version: MEUSec – Method for Enhancing User Experience and Information Security. 2025. In: Proceedings of the 22nd International Conference on Advances in Mobile Computing & Multimedia Intelligence (MoMM2024). Bratislava, Slovakia. <a href="https://doi.org/10.1007/978-3-031-78049-3_5">https://doi.org/10.1007/978-3-031-78049-3_5 </a></strong></em></p>
INFORMATION SECURITY IN THE ERA OF THE DIGITAL ECONOMY: CHALLENGES AND STRATEGIES. INNOVATIVE APPROACHES TO SOLVING ECONOMIC CHALLENGES
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Detailed Artifacts of the Paper "A Case Study of the MEUSec Method to Enhance User Experience and Information Security of Digital Identity Wallets"
<p><strong>Detailed Artifacts of the Paper:</strong> <em><strong>A case study of the MEUSec method to enhance user experience and information security of digital identity wallets. 2025. Journal of Interactive Media (i-com). <a href="https://doi.org/10.1515/icom-2024-0057" target="_blank" rel="noopener">https://doi.org/10.1515/icom-2024-0057</a> </strong></em></p> <p>The artifacts were obtained by applying the MEUSec method to the Hidy wallet which was at an early stage of development.</p> <p> </p>
A Verification Technique for Real-Time Information Flow Security
<p>Evaluation artifacts accompanying the PhD thesis of Christopher Gerking, concerning the chapter on "A Verification Technique for Real-Time Information Flow Security".</p>
Ontology for Information Security in Android Smartphones - SegDinAndroid
<p>Recent social changes have turned the smartphone into a central piece of technology, with complexities linked to essential activities such as instant communication, email management, web browsing, and photo capturing. Despite the benefits, IT experts and managers face challenges in information security , especially concerning information systems. It is important to highlight that Information Systems Theories emphasize the importance of security for devices like the Android smartphone. Researchers suggest that ontologies could be a solution, defining knowledge structures to facilitate shared understanding. The development of an ontology is proposed to assist IT managers in dynamic security on the Android smartphone, focusing on information systems, utilizing a systematic literature review and the Methontology Methodology. This ontology aims to standardize concepts and facilitate information sharing for risk analysis , vulnerabilities, and threats.</p>
IT Policies and Standards - Security of Information Technology
The documents contained in this dataset reflect NASA's comprehensive IT policy in compliance with Federal Government laws and regulations.
IT Policies and Standards - NASA Information Security Policy
The documents contained in this dataset reflect NASA's comprehensive IT policy in compliance with Federal Government laws and regulations.
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