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Dataset results
217 results for “Juvenile Idiopathic Arthritis”
Microbiota study Juvenile Idiopathic Arthritis AG Chang
<p>We have investigated a juvenile idiopathic arthritis (JIA) cohort and paediatric healthy controls (pHC) by our multi-parameter microbiota flow cytometry approach to characterise the microbiota on single-cell level for attributes of the disease. The microbiota is isolated from stool samples and stained according to the published protocol for (a) host immunoglobulins IgA1, IgA2, IgM, IgG and (b) agglutinin binding to mannose, galactose or N-Acetyl-glucosamine surface sugar moieties. For all samples we also determined the microbiome composition by 16S rRNA (V3-V4) sequencing on the illumina MiSeq platform. We provide the raw .fcs and FASTQ files of 54 JIA patients and 38 paediatric controls. For comparison towards disease progression, we additionally analysed 16 rheumatoid arthritis (RA) patients and 18 adult healthy donors (aHC).</p> <p>All .fcs files were generated on <span>BD Influx®.</span></p> <p> </p> <p>The metadata is collected in the provided meta_JIA.csv.</p> <p><span>The staining parameters are summarized in provided panel.csv. </span></p>
An Open-label, Ascending, Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Polyarticular-course Juvenile Idiopathic Arthritis (pcJIA)
ClinicalTrials.gov study NCT02776735. IPD Sharing: YES. Countries: 15. Publications: 0.
A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS)
ClinicalTrials.gov study NCT01230827. IPD Sharing: Not stated. Countries: 12. Publications: 1.
A Study of Ixekizumab (LY2439821) in Children With Juvenile Idiopathic Arthritis Categories of Enthesitis-related Arthritis (Including Juvenile Onset Ankylosing Spondylitis) and Juvenile Psoriatic Art
ClinicalTrials.gov study NCT04527380. IPD Sharing: YES. Countries: 12. Publications: 0.
Pharmacokinetics, Efficacy and Safety of Abatacept Administered Subcutaneously (SC) in Children and Adolescents With Active Polyarticular Juvenile Idiopathic Arthritis (pJIA) and Inadequate Response (
ClinicalTrials.gov study NCT01844518. IPD Sharing: Not stated. Countries: 12. Publications: 6.
A Safety Study of VIMOVO in Adolescents With Juvenile Idiopathic Arthritis (JIA)
ClinicalTrials.gov study NCT01544114. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of Tocilizumab in Patients With Active Polyarticular Juvenile Idiopathic Arthritis
ClinicalTrials.gov study NCT00988221. IPD Sharing: Not stated. Countries: 15. Publications: 4.
A Study to Evaluate the Pharmacokinetics, Efficacy and Safety of Intravenous Golimumab in Pediatric Participants With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate The
ClinicalTrials.gov study NCT02277444. IPD Sharing: Not stated. Countries: 9. Publications: 2.
A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macr
ClinicalTrials.gov study NCT03311854. IPD Sharing: Not stated. Countries: 5. Publications: 2.
Efficacy, Safety, Pharmacokinetics and Immunogenicity Study of Abatacept Administered Intravenously to Treat Active Polyarticular-course Juvenile Idiopathic Arthritis in Japan
ClinicalTrials.gov study NCT01835470. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Flare Prevention Study of Canakinumab in Patients With Active Systemic Juvenile Idiopathic Arthritis (SJIA)
ClinicalTrials.gov study NCT00889863. IPD Sharing: Not stated. Countries: 19. Publications: 4.
A Study of Subcutaneously (SC) Administered Tocilizumab (TCZ) in Participants With Polyarticular-Course Juvenile Idiopathic Arthritis (pJIA)
ClinicalTrials.gov study NCT01904279. IPD Sharing: Not stated. Countries: 12. Publications: 1.
Pharmacokinetics Of CP-690,550 In Pediatric Patients With Juvenile Idiopathic Arthritis (JIA)
ClinicalTrials.gov study NCT01513902. IPD Sharing: Not stated. Countries: 4. Publications: 2.
Single Patient Use of Tocilizumab in Systemic Onset Juvenile Idiopathic Arthritis
ClinicalTrials.gov study NCT00868751. IPD Sharing: Not stated. Countries: 1. Publications: 1.
An Open-label Extension Study of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis and Active Systemic Manifestations Manifestations and Response Characterization Study in Canakinuma
ClinicalTrials.gov study NCT00891046. IPD Sharing: Not stated. Countries: 21. Publications: 2.
Single-dose Study to Assess Efficacy of Canakinumab (ACZ885) in Patients With Active Juvenile Idiopathic Arthritis (SJIA)
ClinicalTrials.gov study NCT00886769. IPD Sharing: Not stated. Countries: 22. Publications: 4.
Long-Term Safety Study Of Tofacitinib In Patients With Juvenile Idiopathic Arthritis
ClinicalTrials.gov study NCT01500551. IPD Sharing: YES. Countries: 19. Publications: 2.
Sleep Shared-Management Intervention for Children With Juvenile Idiopathic Arthritis
ClinicalTrials.gov study NCT04066205. IPD Sharing: NO. Countries: 1. Publications: 1.
Human Anti-Tac (Daclizumab) to Treat Juvenile Idiopathic Arthritis (JIA)-Associated Uveitis
ClinicalTrials.gov study NCT00130637. IPD Sharing: NO. Countries: 1. Publications: 2.
Open Label, Multicentre Trial to Assess Safety and Efficacy of ITF2357 in Active Systemic Juvenile Idiopathic Arthritis
ClinicalTrials.gov study NCT00570661. IPD Sharing: Not stated. Countries: 2. Publications: 2.
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