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50 results for “Left atrium”
Left Atrium 3D Models Extracted from Static CT Images (AF and SR Models)
<p>A cohort of 45 x 2 patient-specific 3D-models from static computed tomography (CT) images provided by the University Medical Center Hamburg-Eppendorf in Germany. The study complies with EU Regulation 2016/679 and has recieved ethical approval from the regional committee. </p> <p>The cohort has been used in two research papers:</p> <ol> <li>Kjeldsberg et al. (2024), Estimation of inlet flow rate in simulations of left atrial flows: A proposed optimized and reference-based algorithm with application to sinus rhythm and atrial fibrillation, <em>J Biomech</em> [Accepted]</li> <li>Kjeldsberg et al. (2024), Beyond CHA2DS2–VASc: hemodynamic and morphologic discriminants for thrombus formation and stroke in atrial fibrillation patients,<em> Ann. Biomed. Eng</em>. [Submitted]</li> </ol> <p><strong>models_af.zip </strong>contains 45 3D surface models (.vtp) extracted during onset of atrial diastole where <strong>A</strong>trial <strong>F</strong>ibrillation movement was applied using a motion algorithm [*]</p> <p><strong>models_sr.zip </strong>contains 45 3D surface models (.vtp) extracted during onset of atrial diastole where <strong>S</strong>inus <strong>R</strong>hytmn movement was applied using a motion algorithm [*]</p> <p> </p> <p>[*] For details on the motion algorithm, see <a href="Harrison, J., 2024. Medical Imaging, Shapes and Statistics for Stroke Prediction in Atrial Fibrillation (Doctoral dissertation, Inria & Université Cote d'Azur, CNRS, I3S, Sophia Antipolis, France).">Harrison – Medical Imaging, Shapes and Statistics for Stroke Prediction in Atrial Fibrillation </a></p>
Prevalence of endoepicardial asynchrony and breakthrough patterns in a bilayer computational model of heterogeneous endoepicardial dissociation in the left atrium
Open the record for dataset details and reuse information.
The differential inflammatory infiltration and gene expression in left and right atrium in patients with atrial fibrillation
<p><strong>Background: </strong>The difference between left and right atrium in Atrial fibrillation (AF) is still lacking. In the present study, we aimed to identify differences in immune infiltration and differentially expressed genes (DEGs) between atrial tissue in patients with AF and sinus rhythm (SR), and to compare the differences between left and right atrial tissues in AF.</p> <p><strong>Methods:</strong> The gene data of GSE79768, GSE115574, and GSE128188 from the Gene Expression Omnibus (GEO) database were retrieved. After merging all data and adjusting batch effect, DEGs were identified. Single-Sample Gene Set Enrichment Analysis (ssGESA), Functional enrichment analyses based on Gene Ontology (GO) resource, Kyoto Encyclopedia of Genes and Genomes (KEGG) resource, ESTIMATE algorithm were carried out to analyze the difference between AF and SR.</p> <p><strong>Results:</strong> In total, 105 atrial samples from 3 studies were included in the analysis. Compared with SR, AF tissue had more CD8 T cells (P = 0.039) and Th2 cells (P = 0.016), and it had fewer Th17 cells (P = 0.008), Tgd (P < 0.001) and NK CD56dim cells (P = 0.047). The differences between the left and right atrium in AF and SR were analyzed. In AF atrium tissue, a total of 88 DGEs (26 up-regulated, 61 down-regulated) were obtained. The enrichment signaling pathways and biological functions of DGEs were predicted.</p> <p><strong>Conclusions:</strong> The differing immune infiltrating cells and DEGs in left and right atrium indicate that there are different mechanisms for development remodeling and inflammatory environment of AF within the left and right atrium.</p>
V-LAP™ Left Atrium Monitoring systEm for Patients With Chronic sysTOlic & Diastolic Congestive heaRt Failure
ClinicalTrials.gov study NCT03775161. IPD Sharing: NO. Countries: 2. Publications: 3.
Left-Atrium-Appendage Occluder Register - GErmany
ClinicalTrials.gov study NCT02230748. IPD Sharing: NO. Countries: 1. Publications: 2.
Endocardial Mapping of Left Atrium for Evaluation of Concomitant Surgical Ablation Lesions
ClinicalTrials.gov study NCT05714800. IPD Sharing: NO. Countries: 1. Publications: 5.
Effect of Structural Remodeling on Scar Formation as Assessed by DE-MRI of the Left Atrium
ClinicalTrials.gov study NCT01187914. IPD Sharing: Not stated. Countries: 0. Publications: 6.
Non - Invasive Evaluation of the Left Atrium Anatomy and Function
ClinicalTrials.gov study NCT03551158. IPD Sharing: NO. Countries: 1. Publications: 11.
Using Left Atrium Appendage Closure in NVAF Patients With High Risk of Ischemic Stroke
ClinicalTrials.gov study NCT04479722. IPD Sharing: YES. Countries: 1. Publications: 0.
Left Atrium Substrate Based Ablation Plus Circumferential Pulmonary Vein Isolation to Treat Chronic Atrial Fibrillation
ClinicalTrials.gov study NCT01716143. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Left Atrium Reservoir Function Modulation in Patients With Atrial Fibrillation: Digoxin Versus Beta Blocker
ClinicalTrials.gov study NCT05540600. IPD Sharing: NO. Countries: 1. Publications: 5.
Effect of ARNI in Patients With Persistent AF and Enlarged Left Atrium After Catheter Ablation
ClinicalTrials.gov study NCT03791723. IPD Sharing: NO. Countries: 0. Publications: 2.
ATAC-seq from left cardiac atrium (ENCSR330WUK)
GEO Series GSE215704. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
long read RNA-seq from left cardiac atrium (ENCSR424QFN)
GEO Series GSE219818. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
ATAC-seq from left cardiac atrium (ENCSR310UDW)
GEO Series GSE170327. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
total RNA-seq from left cardiac atrium (ENCSR652PHZ)
GEO Series GSE175041. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
total RNA-seq from left cardiac atrium (ENCSR993IPO)
GEO Series GSE175350. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
snRNA-seq from left cardiac atrium (ENCSR463EEP)
GEO Series GSE286724. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic profile analysis of the left atrium in spontaneously hypertensive rats at the early stage
GEO Series GSE207283. Rattus norvegicus. 12 samples. Type: Expression profiling by high throughput sequencing.
ATAC-seq from left cardiac atrium (ENCSR390SLL)
GEO Series GSE170758. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.