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382 results for “Left ventricle”
Full summary statistics of mixQTL for GTEx v8 Heart_Left_Ventricle
The mixQTL method is described in paper doi.org/10.1101/2020.04.22.050666. Please cite the original paper if using the data.
Liver and Left Ventricle RNAseq data
<p>Raw count files and normalised read count with differential gene expression analysis results files for both liver and left ventricle.</p>
Conduction in the Right and Left Ventricle is Differentially Regulated by Protein Kinases and Phosphatases: Implications for Arrhythmogenesis
<p>Movies of paced activation and of arrhythmia acquired during perfusion of isolated rabbit hearts with CaMKII inhibitor KN93 or PKA inhibitor H89</p>
Natriuretic Peptide System as Therapy in Human Preclinical Left Ventricle Dysfunction
ClinicalTrials.gov study NCT00387621. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Nesiritide Therapy to Preserve Function of the Left Ventricle After Myocardial Infarction
ClinicalTrials.gov study NCT00573144. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Cardiac structure discontinuities revealed by ex-vivo microstructural characterization. A focus on the basal inferoseptal left ventricle region
<p>Data and materials regarding the submission of the paper. See Data Avaibility section and https://github.com/valeryozenne/Cardiac-Structure-Database for more information and code.</p>
A comprehensive experimental analysis of the local passive response across the healthy porcine left ventricle
<p>This work provides a comprehensive characterization of porcine myocardial tissue, combining biaxial (Bx), simple triaxial shear (STS) and confined compression (CC) tests to analyze its elastic behavior under cyclic loads. We expanded this study to different zones of the ventricular free wall, providing insights into the local behavior along the longitudinal and radial coordinates. The aging impact was also assessed by comparing two age groups (4 and 8 months). Resulting data showed that the myocardium exhibits a highly nonlinear hyperelastic and incompressible behavior. We observed an anisotropy ratio of 2-2.4 between averaged peak stresses in Bx tests and 1-0.59-0.41 orthotropy ratios for normalised fiber-sheet-normal peak stresses in STS tests. We obtained a highly incompressible response, reaching volumetric pressures of 2-7 MPa for perfused tissue in CC tests, with notable differences when fluid drainage was allowed, suggesting a high permeability. Regional analysis showed reduced stiffness and anisotropy (20-25%) at the apical region compared to the medial, which we attributed to differences in the fiber field dispersion. Compressibility also increased towards the epicardium and apical regions. Regarding age-related variations, 8-month animals showed stiffer response (at least 30% increase), particularly in directions where the mechanical stress is absorbed by collagenous fibers (more than 90%), as supported by a histological analysis. Although compressibility of perfused tissue remained unchanged, permeability significantly reduced in 8-month-old animals. Our findings offer new insights into myocardial properties, emphasizing on local variations, which can help to get a more realistic understanding of cardiac mechanics in this common animal model.</p>
MOVIE#1 -Conduction in the Right and Left Ventricle is Differentially Regulated by Protein Kinases and Phosphatases: Implications for Arrhythmogenesis.
<p>Movie of paced activation acquired during perfusion of an isolated rabbit heart with CaMKII inhibitor KN93</p>
MOVIE#4 -Conduction in the Right and Left Ventricle is Differentially Regulated by Protein Kinases and Phosphatases: Implications for Arrhythmogenesis.
<p>Movie of arrhythmia acquired during perfusion of an isolated rabbit heart with PKA inhibitor H89.</p>
MOVIES#1-4 -Conduction in the Right and Left Ventricle is Differentially Regulated by Protein Kinases and Phosphatases: Implications for Arrhythmogenesis.
<p>Movies of paced activation and of arrhythmia acquired during perfusion of isolated rabbit hearts with CaMKII inhibitor KN93 or PKA inhibitor H89.</p>
MOVIE#3 -Conduction in the Right and Left Ventricle is Differentially Regulated by Protein Kinases and Phosphatases: Implications for Arrhythmogenesis.
<p>Movie of paced activation acquired during perfusion of an isolated rabbit heart with PKA inhibitor H89</p>
MOVIE#2 -Conduction in the Right and Left Ventricle is Differentially Regulated by Protein Kinases and Phosphatases: Implications for Arrhythmogenesis.
<p>Movie of arrhythmia acquired during perfusion of an isolated rabbit heart with CaMKII inhibitor KN93.</p>
heart_left_ventricle
<p>small RNASeq dataset from GTEX heart left ventricle data.</p>
Valsartan to Prevent Left Ventricle Remodeling in Pacemaker Patients
ClinicalTrials.gov study NCT01805804. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Conduction System Stimulation to Avoid Left Ventricle Dysfunction
ClinicalTrials.gov study NCT06026683. IPD Sharing: NO. Countries: 1. Publications: 1.
Left Septal Pacing or Left Bundle Branch Pacing to Avoid Left Ventricle Systolic Dysfunction
ClinicalTrials.gov study NCT06707662. IPD Sharing: YES. Countries: 1. Publications: 1.
Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left Ventricle
ClinicalTrials.gov study NCT03079401. IPD Sharing: NO. Countries: 1. Publications: 4.
Safety and Performance of Electrodes Implanted in the Left Ventricle
ClinicalTrials.gov study NCT01905670. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Will Elevated Left Ventricle Filling Pressures Decrease by a Group Exercise Program in Patients With Hypertrophic CardioMyopathy?
ClinicalTrials.gov study NCT03537183. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)
ClinicalTrials.gov study NCT02661451. IPD Sharing: Not stated. Countries: 3. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.