Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
340
datasets available to search
ShareScore release 0.9.0
Dataset results
340 results for “Medical devices”
Clinical evidence for high-risk CE-marked medical devices for glucose management: a systematic review and meta-analysis
<p><strong><span>Aims: </span></strong><span>High-risk medical devices are increasingly used in diabetes management, but<span><span> there are no specific European recommendations on how they should be evaluated. Within</span></span> the Coordinating Research and Evidence for Medical Devices (CORE-MD) project, we conducted a systematic review and meta-analysis evaluating CE-marked high-risk devices for glucose management. </span></p> <p><strong><span>Materials and Methods: </span></strong><span>We<span> identified interventional and observational studies evaluating the </span>efficacy and safety of 8 automated insulin delivery (AID) systems, 2 implantable insulin pumps, and 3 implantable continuous glucose monitoring (CGM) devices.<span> </span></span><span>We meta-analysed randomized controlled trials (RCTs) comparing AID systems with other treatments.</span></p> <p><strong><span>Results:</span></strong><span> 99 studies published from 2009–2022 were included, comprising 83 on AID systems, 6 on insulin pumps, and 10 on CGM; 43% reported industry funding;30% were pre-market; 45% had a comparator group. 33% were RCTs, 25% non-randomized trials, and 41% observational studies. Median sample size was 52 (interquartile range 25–111), age 37.8 years (17–45.5), and study duration 13 weeks (4.5–26). AID systems lowered HbA1c by 0.3 percentage points (absolute mean difference [MD]=-0.3; 9 RCTs; I<sup>2</sup>=85%) and increased time in target range for sensor glucose level by 10.5 percentage points (MD=10.5; 14 RCTs; I<sup>2</sup>=89%). 69% of studies reported on at least one safety outcome.</span></p> <p><strong><span>Conclusions:</span></strong><span> High-risk devices for glucose monitoring or insulin dosing, in particular AID systems, improve glucose control safely but evidence on diabetes-related end organ damage is lacking due to short study durations. Methodological heterogeneity highlights the need for d<span><span>eveloping standards for future pre- and post-market investigations of diabetes-specific high-risk medical devices.</span></span></span></p>
CED schemes on Medical devices in Europe
<p>The attached dataset contains detailed information on CED schemes for medical devices which were in operation in the years between 2015 and 2020 in Europe. This dataset is one of the outputs of a broader research work aiming at exploring the characteristics and challenges of CED schemes for devices in Europeproject.</p>
Careers in Science and Healthcare - How changes to medical device regulation have increased training needs
<p>Article contributed to Careers in Science and Healthcare report.</p>
Quality and Utility of European Cardiovascular and Orthopaedic Registries for the Regulatory Evaluation of Medical Device Safety and Performance Across the Implant Lifecycle: A Systematic Review - Dataset
<p><strong>Background: </strong>The European Union Medical Device Regulation (MDR) requires manufacturers to undertake post-market clinical follow-up (PMCF) to assess the safety and performance of their devices following approval and Conformité Européenne (CE) marking. The quality and reliability of device registries for this Regulation have not been reported. As part of the Coordinating Research and Evidence for Medical Devices (CORE-MD) project, we identified and reviewed European cardiovascular and orthopaedic registries to assess their structures, methods, and suitability as data sources for regulatory purposes.</p> <p><strong>Methods: </strong>Regional, national and multi-country European cardiovascular (coronary stents and valve repair/replacement) and orthopaedic (hip/knee prostheses) registries were identified using a systematic literature search. Annual reports, peer-reviewed publications, and websites were reviewed to extract publicly available information for 33 items related to structure and methodology in six domains and also for reported outcomes.</p> <p><strong>Results: </strong>Of the 20 cardiovascular and 26 orthopaedic registries fulfilling eligibility criteria, a median of 33% (IQR: 14%-71%) items for cardiovascular and 60% (IQR: 28%-100%) items for orthopaedic registries were reported, with large variation across domains. For instance, no cardiovascular and 16 (62%) orthopaedic registries reported patient/ procedure-level completeness. No cardiovascular and 5 (19%) orthopaedic registries reported outlier performances of devices, but each with a different outlier definition. There was large heterogeneity in reporting on items, outcomes, definitions of outcomes, and follow-up durations.</p> <p><strong>Conclusion: </strong>European cardiovascular and orthopaedic device registries could improve their potential as data sources for regulatory purposes by reaching consensus on standardised reporting of structural and methodological characteristics to judge the quality of the evidence as well as outcomes.</p>
Hybrid Market- and Community-Driven Strategy for Repurposing Devices for Medical Use
<p>There is a split in today's technological development between traditional proprietary-based and open community-driven development. Open development ( open science / open software / open hardware ) often loses steam when capital and long-term commitment is required. Proprietary-based development solves the issue by attracting capital, but the need minimize and compensate risks leads to secrecy and a focus on developed economies.<br> <br> Here I propose a strategy to reconcile the two worlds. I focus on the scenario of off-the-shelf devices that can be repurposed for meeting needs in the medical field, as it can lower the typically high initial capital required in the medical device sector while motivating community involvement. The strategy is contingent on the owner of the initial technology not being deprived of its intellectual property rights.<br> <br> This is a work in progress that will be updated through my own involvement and that of any interested bodies.</p>
Dataset for a publication: "Silver-enriched Microdomain Patterns as Advanced Bactericidal Coatings for Polymer-based Medical Devices"
<p>The data set contains the data that were used within the article "Silver-enriched Microdomain Patterns as Advanced Bactericidal Coatings for Polymer-based Medical Devices".</p> <p> </p> <p> </p>
Risky Play: A Risk-based Case Study for Common Mode Current Assessment of a Medical Plasma Device (Dataset)
<p>This dataset contains raw- and de-embedding data which are the source of the referenced publication's plots.</p> <p>Uploaded are raw common mode current measurements in dBm as a .mat file, touchstone files for the cable used and characteristics of the Fischer Customs Communication F-75 and F-2000 probes as .csv, both used for de-embedding cable and current probe from the raw data. </p> <p>In addition, touchstone files of the input impedance measurements are contained.</p> <p>This research is part of a project that has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 955816 (MSCA-ETN ETERNITY)</p>
Insertion of an Intrauterine Device (IUD) After Medical Abortion
ClinicalTrials.gov study NCT00621543. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Open-label Study to Assess Usability of the Medical Information Device #1 (MIND1) System in Adults With Schizophrenia On Oral Aripiprazole
ClinicalTrials.gov study NCT02219009. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Safety and Effectiveness Study of the Ensure Medical Vascular Closure Device
ClinicalTrials.gov study NCT00345631. IPD Sharing: Not stated. Countries: 1. Publications: 1.
EmoLED Medical Device Treatment of Second and Third Stage Pressure Ulcers
ClinicalTrials.gov study NCT05130814. IPD Sharing: Not stated. Countries: 1. Publications: 1.
CE Mark Study for the Harpoon Medical Device in Poland
ClinicalTrials.gov study NCT02432196. IPD Sharing: NO. Countries: 1. Publications: 3.
A Clinical Study With the Medical Device PowerSpiral for Endoscopic Retrograde Cholangio-Pancreatography (ERCP)
ClinicalTrials.gov study NCT05129449. IPD Sharing: NO. Countries: 3. Publications: 1.
Community Empowerment to Pilot a Novel Device for Monitoring Rescue Medication Use in Urban Children With Asthma
ClinicalTrials.gov study NCT02517047. IPD Sharing: Not stated. Countries: 1. Publications: 12.
Monitoring Medication Adherence in Left Ventricular Assist Device Recipients
ClinicalTrials.gov study NCT02388386. IPD Sharing: YES. Countries: 1. Publications: 4.
Immediate Versus Delayed Insertion of the Copper Intrauterine Device (IUD) After Medication Abortion
ClinicalTrials.gov study NCT00737178. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK)
ClinicalTrials.gov study NCT05950984. IPD Sharing: NO. Countries: 1. Publications: 1.
A Clinical Study With the Medical Device PowerSpiral for Deep Enteroscopy
ClinicalTrials.gov study NCT03955081. IPD Sharing: NO. Countries: 6. Publications: 1.
Substudy 'B' of the Accuracy of Ingestible Event Marker (IEM) Detection by the Medical Information Device #1 (MIND1)
ClinicalTrials.gov study NCT02404532. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Substudy of the Accuracy of Ingestible Event Marker (IEM) Detection by the Medical Information Device #1 (MIND1)
ClinicalTrials.gov study NCT02091882. IPD Sharing: YES. Countries: 1. Publications: 3.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.