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61 results for “Molecular Switches”
Figure 1 in Molecular evidence on evolutionary switching from particle-feeding to sophisticated carnivory in the calanoid copepod family Heterorhabdidae: drastic and rapid changes in functions of homologues
Figure 1. Morphology-based phylogenetic trees of the heterorhabdids. A and B, Ohtsuka et al. (1997); C, Park (2001).
Linked collectors and determiners for: A molecular phylogeny and revision of the genus Pyropteron Newman, 1832 (Lepidoptera, Sesiidae) reveals unexpected diversity and frequent hostplant switch as a driver of speciation.
Natural history specimen data linked to collectors and determiners held within, "A molecular phylogeny and revision of the genus Pyropteron Newman, 1832 (Lepidoptera, Sesiidae) reveals unexpected diversity and frequent hostplant switch as a driver of speciation". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="https://bionomia.net/dataset/cdd9688e-9a3f-4602-992e-1f8693caab9b">https://bionomia.net/dataset/cdd9688e-9a3f-4602-992e-1f8693caab9b</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/cdd9688e-9a3f-4602-992e-1f8693caab9b">https://gbif.org/dataset/cdd9688e-9a3f-4602-992e-1f8693caab9b</a>. Formatted as a Frictionless Data package.
Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism - Dataset IC
<p>Raw data associated to the following publication: “Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism".</p> <p><em>The stress-responsive FKBP51 controls body weight gain by regulating the balance between autophagy and mTOR signaling. We identified FKBP51 as a central nexus for the recruitment of the LKB1/AMPK complex to WIPI4 and TSC2 to WIPI3, thereby regulating the balance between autophagy and mTOR signaling in response to metabolic challenges. MBH FKBP51 dose-dependently regulates autophagy both in the brain as well as in peripheral metabolic tissues. Consequently, deletion of MBH FKBP51 strongly induces obesity, while its overexpression protects against high-fat diet (HFD) induced obesity.</em></p> <p>IC data in Thermo RAW data format; 2nd of 2 datasets.</p>
Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism - Dataset Bz
<p>Raw data associated to the following publication: “Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism".</p> <p><em>The stress-responsive FKBP51 controls body weight gain by regulating the balance between autophagy and mTOR signaling. We identified FKBP51 as a central nexus for the recruitment of the LKB1/AMPK complex to WIPI4 and TSC2 to WIPI3, thereby regulating the balance between autophagy and mTOR signaling in response to metabolic challenges. MBH FKBP51 dose-dependently regulates autophagy both in the brain as well as in peripheral metabolic tissues. Consequently, deletion of MBH FKBP51 strongly induces obesity, while its overexpression protects against high-fat diet (HFD) induced obesity.</em></p> <p>Bz data in Thermo RAW data format; 1 of 2 datasets.</p>
Use of A Molecular Switch Probe to Activate or Inhibit GIRK1 Heteromers In Silico Reveals a Novel Gating Mechanism
<p>GIRK channel structure models (PDB structure files) used for Molecular Dynamics simulations.</p>
Supplementary Info for 'The molecular circuitry regulating the switch between iron deficiency and overload in mice.'
<p>Supplementary Data for </p> <p>Mok, H., Mlodnicka, A.E., Hentze, M.W., Muckenthaler, M. and Schumacher, A., 2006. The molecular crcuitry regulating the switch between iron deficiency and overload in mice. <em>Journal of Biological Chemistry</em>, <em>281</em>(12), pp.7946-7951.</p>
Early Switch From First-Line Docetaxel/Prednisone to Cabazitaxel/Prednisone and the Opposite Sequence, Exploring Molecular Markers in Men With Metastatic Castration-Resistant Prostate Cancer (mCRPC)
ClinicalTrials.gov study NCT01718353. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Figure 2 in Molecular evidence on evolutionary switching from particle-feeding to sophisticated carnivory in the calanoid copepod family Heterorhabdidae: drastic and rapid changes in functions of homologues
Figure 2. Phylogenetic tree based on the 18S + 28S rRNA genes of heterorhabdids. The numbers on branches indicate bootstrap values (maximum likelihood, ML) and posterior probability (Bayesian inference, BI). Two metridinids (Metridia effusa and Pleuromamma abdominalis) were chosen as the outgroup taxa. The star (Node ★) indicates the innovation of a poison-injection system.
Investigation of an anomolous 3'-termini mismatch bypass for phosphorothioated primers and application as molecular switch
Open the record for dataset details and reuse information.
Data for "A massively parallel double selection workflow for the evolution of molecular switches based on surface-display in Escherichia coli" by Givelet, et al., 2023
<p>Data related to a publication on "A massively parallel double selection workflow for the evolution of molecular switches based on surface-display in Escherichia coli"</p> <p> </p> <p>The data contains</p> <p>- FACS data for the images (organized in folders)<br> - images (tiff and jpg)<br> - sequence data (fasta)<br> - one video (mov)</p>
Molecular switching of a DNA-sliding clamp to a repressor mediates long-range gene silencing
GEO Series GSE274567. Escherichia coli. 12 samples. Type: Other.
Mycobacterium tuberculosis Exploits a Molecular Off Switch of the Immune System for Intracellular Survival
GEO Series GSE108363. Homo sapiens. 186 samples. Type: Expression profiling by array.
Transcriptional analysis of transcription factor c-Maf as a molecular switch that controls immune suppression by programming macrophages in lung cancer
GEO Series GSE139541. Mus musculus. 6 samples. Type: Expression profiling by array.
A postnatal molecular switch drives the activity-dependent maturation of parvalbumin interneurons.
GEO Series GSE256443. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing; Other.
Molecular reprogramming and phenotype switching in Staphylococcus aureus lead to high antibiotic persistence and affect therapy success
GEO Series GSE148024. Staphylococcus aureus. 18 samples. Type: Expression profiling by high throughput sequencing.
A postnatal molecular switch drives the activity-dependent maturation of parvalbumin interneurons [CUT&RUN]
GEO Series GSE256442. Mus musculus. 3 samples. Type: Other.
A Molecular Switch from Tumor Suppressor to Oncogene in ER-Positive Breast Cancer: Role of Androgen Receptor, JAK-STAT, and Lineage Plasticity
GEO Series GSE274731. Homo sapiens. 102 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Molecular insights into the lipid-carbohydrates metabolism switch under the endurance effort in Arabian horses
GEO Series GSE226819. Equus caballus. 20 samples. Type: Expression profiling by high throughput sequencing.
The VviNAC33 acts as a molecular switch by activating leaf degreening and repressing vegetative growth during the immature-to-mature phase transition in grapevine
GEO Series GSE156105. Vitis vinifera. 6 samples. Type: Expression profiling by array.
A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex [ChIP-seq]
GEO Series GSE254690. Mus musculus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.