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14 results for “Mus musculus domesticus; Mus musculus”
The genetics of immune and infection phenotypes in wild mice, Mus musculus domesticus
<p><span>Wild animals are under constant threat from a wide range of micro- and macroparasites in their environment. Animals make immune responses against parasites, and these are important in affecting the dynamics of parasite populations. Individual animals vary in their anti-parasite immune responses. Genetic polymorphism of immune-related loci contributes to inter-individual differences in immune responses, but most of what we know in this regard comes from studies of humans or laboratory animals; there are very few such studies of wild animals naturally infected with parasites. Here we have investigated the effect of Single Nucleotide Polymorphisms (SNPs) in immune-related loci (the MHC, and loci coding for cytokines and Toll-like receptors) on a wide range of immune and infection phenotypes in UK wild house mice, <em>Mus musculus domesticus</em>. We found strong associations between SNPs in various MHC and cytokine-coding loci on both immune measures (antibody concentration and cytokine production) and on infection phenotypes (infection with mites, worms and viruses). Our study provides a comprehensive view of how polymorphism of immune-related loci affects immune and infection phenotypes in naturally infected wild rodent populations.</span></p>
The genetics of immune and infection phenotypes in wild mice, Mus musculus domesticus
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Data from: Immune state is associated with natural dietary variation in wild mice Mus musculus domesticus
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Data from: Paternal Imprinting of Mating Preferences Between Natural Populations of House Mice (Mus musculus domesticus)
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Data from: Genetic structure and invasion history of the house mouse (Mus musculus domesticus) in Senegal, West Africa: a legacy of colonial and contemporary times
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Data from: Steroid hormones in hair reveal sexual maturity and competition in wild house mice (Mus musculus domesticus)
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Data from: Fitness consequences of female alternative reproductive tactics in house mice (Mus musculus domesticus)
Alternative reproductive tactics are defined as discrete differences in morphological, physiological and/or behavioral traits associated with reproduction, which occur within the same sex and population. House mice provide a rare example for alternative reproductive tactics in females, which can either rear their young solitarily, or together with one or several other females in a communal nest. We assessed the fitness consequences of communal and solitary breeding in a wild population to understand how the two tactics can be evolutionarily stable. Females switched between the two tactics (with more than 50% of all females having two or more litters using both tactics), pointing towards communal and solitary breeding being two tactics within a single strategy and not two genetically determined strategies. Communal breeding resulted in reduced pup survival and negatively impacted female reproductive success. Older and likely heavier females more often reared their litters solitarily, indicating that females use a condition dependent strategy. Solitary breeding seems the more successful tactic and only younger and likely less competitive females might opt for communal nursing, even at the cost of increased pup mortality. This study emphasizes the importance of analyzing phenotypic plasticity and its role in cooperation in the context of female ARTs.
Data from: Fitness consequences of female alternative reproductive tactics in house mice (Mus musculus domesticus)
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Testis expression in Mus musculus domesticus x Mus musculus musculus hybrid zone mice
GEO Series GSE61417. Mus musculus; Mus musculus musculus x M. m. domesticus. 190 samples. Type: Expression profiling by array.
Testis expression in Mus musculus domesticus WSB/EiJ x Mus musculus musculus PWD/PhJ F2 hybrids
GEO Series GSE54089. Mus musculus. 331 samples. Type: Expression profiling by array.
Impact of high fat diet on Mus musculus domesticus secreted milk small RNA transcriptome
GEO Series GSE99280. Mus musculus. 9 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Mus musculus domesticus filtered autosomal variants from eastern United States, Germany, and France
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Impact of high fat diet on Mus musculus domesticus secreted milk large RNA transcriptome
GEO Series GSE143205. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Gene expression between high and low altitude Mus musculus domesticus
GEO Series GSE29097. Mus musculus domesticus; Mus musculus. 18 samples. Type: Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.