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24 results for “Mycobacterium avium subsp. paratuberculosis; Mycobacterium avium subsp. avium”
Supplementary Material to article "Molecular Diversity of Mycobacterium avium subsp. paratuberculosis in Four Dairy Goat Herds from Thuringia (Germany)"
<p>These data (supplementary material) belong to the publication "Molecular Diversity of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> in Four Dairy Goat Herds from Thuringia (Germany)". The study determined the diversity of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> (MAP) isolated from four goat herds affected by paratuberculosis in Thuringia (Germany), as well as the detailed distribution of MAP genotypes among the animals and their environment in one herd (herd 1). A combination of three methods was used to genotype isolates from fecal samples of infected goats, from various intestinal and other tissues of clinically affected goats, and from environmental samples. The six MAP-C genotypes identified could be assigned to five different phylogenetic subgroups. The results suggest individual infection strains within each herd. In herd 1, one predominant strain was found, and two strains occurred sporadically. The identified genotypes were not goat specific.</p>
Supplementary dataset to publication: Complete Genome Sequence of Ovine Mycobacterium avium subsp. paratuberculosis Strain JIII-386 (MAP-S/type III) and Its Comparison to MAP-S/type I, MAP-C, and M. avium Complex Genomes.
<p>This is the modified supplemented material to the publication “Complete genome sequence of ovine Mycobacterium avium subsp. paratuberculosis strain JIII-386 (MAP-S/type III) and its comparison to MAP-S/type I, MAP-C, and M. avium complex genomes”.</p> <p>The complete circular genome of Mycobacterium avium subsp. paratuberculosis (MAP) strain JIII-386 from Germany, closed by Nanopore technology in this study, was presented and compared with the draft genome of JIII-386, previously published in [doi:10.1093/gbe/ew154], the closed genome of the MAP-S/type I strain Telford, the MAP-S/type III draft genome of strain S397, twelve closed MAP-C (type II) strains and eight closed Mycobacterium avium (M. a.) strains of subsp. hominissuis (MAH) and subsp. avium (MAA). Structural comparisons clearly revealed the mosaic nature of MAP genomes, the differences between MAP subtypes I, II and III, and the higher diversity of MAP-S compared to MAP-C genomes. </p> <p>The material provides a wealth of detailed results from these analyses and comparisons. These include a list of identified ncRNA and Riboswitches, as well as additional genes in finished JIII-386, the gene content of identified prophage regions, copy number of identified transposable elements and a list of selected virulence-associated genes in the different MAP-type (I - III) strains. The genomic islands identified and included genes along with their predicted functions were presented for six MAP genomes (belonging to MAP-S/type I and III, and MAP-C), one MAH genome and one MAA genome. One table shows the corresponding genomic islands in the genomes of JIII-386, Telford and three MAP-C genomes. Furthermore, homologous genes of known MAP-S specific Large Sequence Polymorphisms regions (LSP<sup>S</sup> = LSP-S) were recorded in different MAP-S type strains, one MAH and one MAA strain, as well as genes of deletions #1 (LSP<sup>A</sup>-20), #2, and s-delta-1, previously described as MAP-S-specific deletions, their presence or absence in 3 MAP-S, 12 MAP-C, 4 MAH, and 4 MAA strains were listed. Different presence or absence of genes, but also identified frameshifts or disruptions of various virulence-associated genes could lead to the different MAP-type specific phenotypic characteristics. Comprehensive core and pan genome analyses (results listed in six tables) revealed unique genes and genes likely to have been acquired by horizontal gene transfer in different MAP types and subtypes, but also emphasized the highly conserved and close relationship, and the complex evolution of M. a. strains.</p> <p> </p>
The role of interleukin-10 receptor alpha (IL10Rα) in Mycobacterium avium subsp. paratuberculosis infection of a mammary epithelial cell line
GEO Series GSE247921. Bos taurus. 16 samples. Type: Expression profiling by high throughput sequencing.
Global host transcriptional profiles following Mycobacterium avium subsp. paratuberculosis infection in mice
GEO Series GSE62836. Mus musculus. 12 samples. Type: Expression profiling by array.
mRNA expression profile of bovine monocyte derived macrophages infected with Mycobacterium avium subsp. Paratuberculosis (MAP)
GEO Series GSE185609. Bos taurus. 6 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Combinatorial discriminant analysis applied to RNAseq data reveals a set of 10 transcripts as signatures of infection of cattle with Mycobacterium avium subsp. Paratuberculosis (MAP).
GEO Series GSE130124. Bos taurus. 15 samples. Type: Expression profiling by high throughput sequencing.
Revealing immune responses in the Mycobacterium avium subsp. paratuberculosis-infected THP-1 cells using single cell RNA-sequencing
GEO Series GSE176294. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profiling of whole-blood in Mycobacterium avium subsp. paratuberculosis-infected cattle
GEO Series GSE62835. Bos taurus. 12 samples. Type: Expression profiling by array.
Mycobacterium avium subsp. paratuberculosis antigens induce cellular immune responses in cattle
GEO Series GSE221544. other sequences; Bos taurus. 384 samples. Type: Other.
miRNA profiling of putative biomarker candidates in Mycobacterium avium subsp. paratuberculosis-infected cattle
GEO Series GSE166230. Bos taurus. 8 samples. Type: Non-coding RNA profiling by high throughput sequencing.
RNA-Seq analysis of ileocecal valve and peripheral blood from Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis
GEO Series GSE137395. Bos taurus. 28 samples. Type: Expression profiling by high throughput sequencing.
The Fur-like regulatory protein MAP3773c modulates key metabolic pathways in Mycobacterium avium subsp. paratuberculosis under in-vitro iron starvation
GEO Series GSE244734. Mycobacterium avium subsp. paratuberculosis. 20 samples. Type: Expression profiling by high throughput sequencing.
The Intracellular Life of Mycobacterium avium subsp. paratuberculosis During Macrophage Stress: A Key Role for the Alternative Sigma Factor, SigH
GEO Series GSE43182. Mycobacterium avium subsp. paratuberculosis K-10. 4 samples. Type: Expression profiling by high throughput sequencing.
Characterization of the Bovine Salivary Gland Transcriptome Associated with Mycobacterium avium subsp. paratuberculosis Experimental Challenge
GEO Series GSE124789. Bos taurus. 39 samples. Type: Expression profiling by high throughput sequencing.
Expression analysis of Mycobacterium avium subsp. paratuberculosis K-10 within macrophage cell line
GEO Series GSE43645. Mycobacterium avium subsp. paratuberculosis K-10. 10 samples. Type: Expression profiling by array.
Exploring transcriptional regulation of Mycobacterium avium subsp. paratuberculosis after human THP-1 cell infection via dual RNA-seq analysis
GEO Series GSE199476. Homo sapiens; Mycobacterium avium subsp. paratuberculosis K-10. 6 samples. Type: Expression profiling by high throughput sequencing.
Mycobacterium avium subsp. paratuberculosis gene transcription in simulated phagosomal environment and in human macrophage infection
GEO Series GSE32243. Mycobacterium avium subsp. paratuberculosis K-10; Mycobacterium avium subsp. paratuberculosis. 2 samples. Type: Expression profiling by array.
Expression data of sheep exposed to Mycobacterium avium subsp. Paratuberculosis
GEO Series GSE114384. Bos taurus; Ovis aries. 124 samples. Type: Expression profiling by array.
Analysis of global gene expressions in initial infection of Mycobacterium avium subsp. paratuberculosis using epithelial cells-peripheral blood mononuclear cells culture passage model.
GEO Series GSE149494. Bos taurus. 12 samples. Type: Expression profiling by high throughput sequencing.
lncRNA expression profile of bovine monocyte derived macrophages infected with Mycobacterium avium subsp. Paratuberculosis
GEO Series GSE193595. Bos taurus. 6 samples. Type: Expression profiling by high throughput sequencing.
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