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11 results for “Nanostructured lipid carriers”
Figure 7 in Inflammation reduction potential of nanostructured lipid carriers encapsulated with rat's bone marrow cells' lysate
Figure 7. In-vivo Gene Expression Analysis: (A) represents apoptotic markers; BAX and Caspase-3, expression in treated nanostructured lipid carriers (T-NLC), treated bone marrow-derived mesenchymal stromal cells (BMSCs) lysate (C-I-BMSCs-L) and NLC loaded BMSCs lysate (C-I-NLC-BMSCs-L) groups as compared to normal (N) and carrageenan injected injury (C) groups (B) shows proinflammatory markers (IL-6 and IL-8) expression levels in treated C-I-BMSCs-L and treated C-I-NLC-BMSCs-L groups as compared to N and C groups (C) shows Proliferative markers (Ki-67, PCNA and TOP2A) expression in treated C-I-BMSCs-L and treated C-INLC-BMSCs-L group as compared to N and C groups. Whereas N-NS represents normal rats injected with normal saline, C-NS represents carrageenan-injected normal saline, C-I-DFS represents carrageenan-injected diclofenac sodium. Where; the* sign shows significance between untreated and treated groups while α and ss sign shows significance between carrageenan injury and other treatment groups. Where, ns is non-significant, * & α represents P<0.05, ** & ss represents P<0.001, *** & αss represents P<0.0001.
Figure 6 in Inflammation reduction potential of nanostructured lipid carriers encapsulated with rat's bone marrow cells' lysate
Figure 6. Percentage inhibition of inflammation at a time interval (hr) in carrageenan-induced rat's hind paw oedema model. The effect of different treatment groups, i.e., normal (N), normal rat paw injected with normal saline (N-NS), carrageenan injected group (C), carrageenan injected with normal saline group (C-NS), carrageenan injected with diclofenac sodium group (C-I-DFS), carrageenan injected with nanostructured lipid carriers group (C-I-NLC), carrageenan injected with bone marrow-derived mesenchymal stromal cells (BMSCs) lysate group (C-I-BMSCs-L) and Carrageenan injected with NLC loaded BMSCs lysate group (C-I-NLC-BMSCs-L); on hind paw oedema at different hours (0, 1 2, 3, 6 & 24 hours). Where; the* sign shows significance between normal and carrageenan-induced treated groups while α and ss sign shows significance between carrageenan injected and carrageenaninduced treatment groups. Where; ns is non-significant, ** & ss denotes P<0.001, *** & αss denotes P<0.0001.
Figure 4 in Inflammation reduction potential of nanostructured lipid carriers encapsulated with rat's bone marrow cells' lysate
Figure 4. (A) Expression analysis of angiogenesis marker vascular endothelial growth factor (VEGF) via immunocytochemistry; (B) Expression analysis of apoptotic marker p53 via immunocytochemistry; (C) Expression analysis of apoptotic marker p53 via immunocytochemistry. Where: Untreated (UT), H 2 O 2 injury (I-H 2 O 2), treated NLC (T-NLC), treated BMSCs lysate (T-BMSCs-L), and treated NLC loaded bone marrow-derived mesenchymal stromal cells lysate (T-NLC-BMSCs-L). Stained cells are red, and blue denotes the nuclei counterstained with 4′,6-diamidine-2′-phenylindole dihydrochloride (DAPI,) while arrows show the positive cells expressing the protein. Scale bar: 200µm.
Figure 2 in Inflammation reduction potential of nanostructured lipid carriers encapsulated with rat's bone marrow cells' lysate
Figure 2. Represents cytotoxicity analysis/percentage cell viability and standardized viability concentration (SVC) values of different treatment groups on NIH 3T3 Cells (A) Represents the percentage of NIH 3T3 cells viability treated with different concentrations of nanostructured lipid carriers (NLC), bone marrow-derived mesenchymal stromal cells lysate (BMSCs-L), and NLC loaded BMSCs lysate (NLC-BMSCs-L). N represents % age viability of normal cells that receive no treatment and no H 2O2 injury; (B) Cytotoxicity analysis of various concentrations (500µg/µL, 1mg/mL, 2mg/mL, and 3mg/mL) of BMSCs lysate (C) SVC of BMSCslysate on NIH 3T3 cells; (D) Cytotoxicity analysis of various concentrations (500µg/µL, 1mg/mL, 2mg/mL, and 3mg/mL) of NLC loaded BMSCs lysate (E) shows SVC of NLC loaded BMSCs lysate on cells. Where; ***P<0.0001, *shows significance between untreated and treated groups while α and ss sign shows significance between H 2O2 injury and other treatment groups, αss shows P<0.0001, and ns is non-significant.
Figure 1 in Inflammation reduction potential of nanostructured lipid carriers encapsulated with rat's bone marrow cells' lysate
Figure 1. (A) Scanning Electron Micrograph of NLC and (B) Scanning Electron Micrograph of NLC-BMSCs-L; (B) Characterization of nanostructured lipid carriers (NLC) loaded bone marrow-derived mesenchymal stromal cells (BMSCs) lysate via enzyme-linked immunosorbent assay (ELISA):vascular endothelial growth factor (VEGF) and interleukin-6 (IL-6) expression in NLC, BMSCs-L, and NLC loaded bone marrow-derived mesenchymal stromal cells lysate (NLC-BMSCs-L).Where; *P<0.05, **P<0.01, ***P<0.0001, ns is non-significant.
Figure 4 from: Fitriani EW, Avanti C, Rosana Y, Surini S (2024) Nanostructured lipid carriers: A prospective dermal drug delivery system for natural active ingredients. Pharmacia 71: 1-15. https://doi.org/10.3897/pharmacia.71.e115849
Figure 4 NLC Preparation Methods: High pressure homogenization; High shear homogenization and ultrasonication, Microemulsion, Solvent emulsification/ evaporation, Membrane contractor, Phase inversion temperature, Coacervation.
Supplementary materials: Development of dihydrooxyresveratrol-loaded nanostructured lipid carriers for effective treatment of hyperpigmentation
Open the record for dataset details and reuse information.
Figure 3 from: Fitriani EW, Avanti C, Rosana Y, Surini S (2024) Nanostructured lipid carriers: A prospective dermal drug delivery system for natural active ingredients. Pharmacia 71: 1-15. https://doi.org/10.3897/pharmacia.71.e115849
Figure 3 Morphological models of different types of nanostructured lipid carriers (NLCs).
Figure 2 from: Fitriani EW, Avanti C, Rosana Y, Surini S (2024) Nanostructured lipid carriers: A prospective dermal drug delivery system for natural active ingredients. Pharmacia 71: 1-15. https://doi.org/10.3897/pharmacia.71.e115849
Figure 2 Morphological models of emulsion, SLN, and NLC.
Figure 1 from: Fitriani EW, Avanti C, Rosana Y, Surini S (2024) Nanostructured lipid carriers: A prospective dermal drug delivery system for natural active ingredients. Pharmacia 71: 1-15. https://doi.org/10.3897/pharmacia.71.e115849
Figure 1 Lipid-based drug delivery system.
Nanostructured Lipid Carriers based mRNA vaccine leads to a T cell–inflamed tumor microenvironment favorable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumor model
GEO Series GSE282402. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
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