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Dataset results
29 results for “Organ dose”
Reference Dataset for Benchmarking Organ Doses Derived from Monte Carlo Simulations of CT Exams
<p>This reference dataset contains CT scanner x-ray source characteristics, filtration profile, de-identified patient image data and size characteristics, voxelized patient models, exam characteristics, x-ray tube current data, and organ dose results in tabular form from Monte Carlo (MC) simulations of abdominal/pelvis CT exams of pregnant patients. This dataset can be used for benchmarking MC simulation codes for CT dosimetry.</p>
Dose coefficients for organ dosimetry in tomosynthesis imaging of adults and pediatrics across diverse protocols
<p>A database of organ dose coefficients using MC simulations for a clinically representative virtual population of adult and pediatric XCAT patient models over an expanded set of 21 exam protocols in digital tomosynthesis. </p>
A Study to Evaluate the Effect of Single-Dose Intravenous Rifampin as a Prototypic Inhibitor of Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 on the Single-Dose Pharmacokinetics (PK) o
ClinicalTrials.gov study NCT04121078. IPD Sharing: YES. Countries: 1. Publications: 1.
A database for benchmarking organ dose estimates and uncertainties in CT
<p>This database includes patient images and associated verified Monte Carlo based estimates of organ doses that may be used for benchmarking different organ dose estimation techniques against a reference standard.</p>
Raw Data for the article: Analysis of the Specific Immune Response after the Third Dose of mRNA COVID-19 Vaccines in Organ Transplant Recipients: Possible Spike-S1 Reactive IgA Signature in Protection from SARS-CoV-2 Infection
<p><strong>Background:</strong> Several studies have indicated that anti-SARS-CoV-2 mRNA vaccinations are less effective in inducing robust immune responses among solid organ transplant recipients (SOTRs) compared with the immunocompetent. The third dose of vaccine in SOTRs showed promising results of immunogenicity, even though clinical studies have suggested that immunocompromised subjects are less likely to build a protective immune response against SARS-CoV-2 resulting in lower vaccine efficacy for the prevention of severe COVID-19. <strong>Methods:</strong> Serological IgG and IgA were analyzed through CLIA or ELISA, respectively, while Spike-specific T cells were detected by ELISpot assay after the second and third dose of vaccine in 43 SOTRs. <strong>Results:</strong> The third dose induced an improvement in antibody response against SARS-CoV-2. We also reported a strong correlation between specific humoral and cellular responses after the third dose, even though we did not see significant changes in the magnitude of the SARS-CoV-2-specific T cell response. SOTRs who contracted the SARS-CoV-2 infection after the third dose, despite eliciting a positive IgG response, failed to mount an anti-Spike-S1 IgA response, both after the third dose and after SARS-CoV-2 infection. <strong>Conclusions:</strong> We can conclude that serum IgA detection can be helpful, along with IgG detection, for the evaluation of vaccine efficacy, principally in fragile subjects at high risk of infection.</p>
Immune Response to Third Dose of COVID-19 Vaccine in Solid Organ Transplant
ClinicalTrials.gov study NCT05124509. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Valganciclovir Dosing in Pediatric Solid Organ Transplant Recipients
ClinicalTrials.gov study NCT02503982. IPD Sharing: NO. Countries: 1. Publications: 1.
CyberKnife Radiosurgery for Organ-Confined Prostate Cancer: Homogenous Dose Distribution
ClinicalTrials.gov study NCT00643994. IPD Sharing: NO. Countries: 1. Publications: 1.
Determinants of Immunosuppressive Dose Requirements in Children After Solid Organ Transplantation
ClinicalTrials.gov study NCT01767350. IPD Sharing: Not stated. Countries: 1. Publications: 17.
A Prospective Study of Daily Adaptive Radiotherapy to Better Organ-at-Risk Doses in Head and Neck Cancer
ClinicalTrials.gov study NCT04883281. IPD Sharing: NO. Countries: 1. Publications: 1.
Standard-dose Versus High-dose Flu Vaccine in Solid Organ Transplant.
ClinicalTrials.gov study NCT01808456. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease
ClinicalTrials.gov study NCT02225132. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Benchmark Dose Modeling Approaches for Volatile Organic Chemicals using a Novel Air-Liquid Interface In Vitro Exposure System
GEO Series GSE199794. Homo sapiens. 555 samples. Type: Expression profiling by high throughput sequencing.
Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
ClinicalTrials.gov study NCT03553212. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Blender Biomarkers: A BLENDER Sub-study to Evaluate the Effect of Oxygen Dose on Oxidative Stress and Organ Injury
ClinicalTrials.gov study NCT05542966. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
High Dose Re-Irradiation Utilizing Advanced Deformable Image Registration (DIR) and Individualized Organ At Risk (OAR) Dose Calculations With Organ Specific Toxicity Analysis
ClinicalTrials.gov study NCT05301101. IPD Sharing: NO. Countries: 1. Publications: 0.
Standard Dose Versus High-Dose Inactivated Flu Vaccine in Pediatric Solid Organ Transplant Patients
ClinicalTrials.gov study NCT01525004. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Dose-Escalation Study Evaluating Safety and Tolerability of Viral-Specific T Cells Against CMV in Adult Solid Organ Transplant Recipients
ClinicalTrials.gov study NCT03950414. IPD Sharing: NO. Countries: 1. Publications: 0.
Sparing of Organs at Risk in High Dose Rate Brachytherapy
ClinicalTrials.gov study NCT01681342. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients
ClinicalTrials.gov study NCT04612413. IPD Sharing: NO. Countries: 5. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.