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101
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ShareScore release 0.9.0
Dataset results
101 results for “POLY I:C”
Lower-poly Liding food vessel, 12th-11th C BCE
This is a low-poly version of [Liding food vessel](https://skfb.ly/6SJnH) - this one is better for mobile and VR/AR. Ancient Chinese bronze food vessel, 12th-11th century BCE, now in the collection of the Minneapolis Institute of Art. From the vessel's description on [artsmia.org](https://new.artsmia.org/) : *"The prototype of the bronze vessel known as li was a coarse pottery version of the same shape and name, made in the later Neolithic period (c. 3000–2000 BCE). These pots served as cooking vessels, mainly for porridge, and featured three prominent hollow legs shaped like pointed lobes. These hollow legs formed an extension of the interior cavity and were designed to expose the contents of the pot to heat most effectively."* More information: https://collections.artsmia.org/art/1113/liding-food-vessel-china Source: Objaverse 1.0 / Sketchfab
Dataset related to article "Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor-conditioned macrophages."
<p>Macrophage plasticity is the ability of mononuclear phagocytes to change phenotype, function, and genetic reprogramming upon encounter of specific local stimuli. In the tumor microenvironment, Tumor-Associated Macrophages (TAMs) acquire an immune-suppressive and tumor-promoting phenotype. With the aim to re-educate TAMs to antitumor effectors, in this study, we used two immunestimulatory compounds: the TLR7 agonist Imiquimod (IMQ) and the TLR3 agonist Poly(I:C). To better mimic in vitro the response of TAMs, we used Tumor-Conditioned Macrophages (TC-Mϕ) differentiated in the presence of tumor cell supernatants. Our results show that TC-Mϕ respond differently from conventional M2-polarized macrophages. Upon stimulation with IMQ, TC-Mϕ did not upregulate major histocompatibility complex (MHC II) molecules and unexpectedly expressed increased CD206. With both compounds, TC-Mϕ produced higher levels of inflammatory cytokines than M2 macrophages. IMQ and Poly(I:C) differed in the types of regulated genes and secreted mediators. Reflecting their signaling pathways, only IMQ significantly induced IL-1β and IL-6, while only Poly(I:C) stimulated CXCL10, and both upregulated CCL5. Of note, using a novel cytotoxicity assay, Poly(I:C), but not IMQ, was effective in triggering the cytotoxic activity of TC-Mϕ against cancer cells. Overall, the results demonstrate that Poly(I:C) stimulation of TC-Mϕ is superior than IMQ in terms of macrophage re-education toward antitumor effectors.</p>
Poly(I:C) exposure during in vitro fertilization disrupts first cleavage of mouse embryos and subsequent blastocyst development
<p>The data of the study about: Poly(I:C) exposure during in vitro fertilization disrupts first cleavage of mouse embryos and subsequent blastocyst development.</p>
Specific induction of TSLP by the viral RNA analogue poly(I:C) in primary epithelial cells derived from nasal polyps
<p>Database with files used for generating the result in this manuscript.</p>
Sequencing experiments on poly(U) polymerase mutants in C. elegans [srna]
GEO Series GSE271568. Caenorhabditis elegans. 27 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Comparison of the expression profiles of wild type (WT) and Oct-6-deficient (Oct-6-/-) macrophages in response to poly(I:C) treatment
GEO Series GSE22691. Mus musculus. 12 samples. Type: Expression profiling by array.
SINGLE-CELL CHARACTERIZATION OF A MODEL OF POLY I:C-STIMULATED PERIPHERAL BLOOD MONONUCLEAR CELLS IN SEVERE ASTHMA
GEO Series GSE172495. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing.
The Poly(C) binding protein Pcbp2, and its retrotransposed derivative Pcbp1, are independently essential to mouse development
GEO Series GSE72491. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
The role of Ch25h in the macrophage response to poly(I:C) (Let1a)
GEO Series GSE54063. Mus musculus. 14 samples. Type: Expression profiling by array.
Multistrain Probiotic Modulation of Intestinal Epithelial Cells' Immune Response to a Double-Stranded RNA Ligand, Poly (I:C)
GEO Series GSE54042. Homo sapiens. 3 samples. Type: Expression profiling by array.
Immune system modulation by the adjuvants Poly (I:C) and Montanide ISA 720
GEO Series GSE203218. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Dendritic cell response to hypoxia and poly I:C
GEO Series GSE24995. Mus musculus. 4 samples. Type: Expression profiling by array.
PIE cell line: Control vs. Poly(I:C) treated or Immunobiotic treated
GEO Series GSE93225. Sus scrofa; Sus scrofa domesticus. 4 samples. Type: Expression profiling by array.
Temperature-dependent regulation of gene expression in Japanese flounder Paralichthys olivaceus treated with poly (I:C)
GEO Series GSE66692. Paralichthys olivaceus. 24 samples. Type: Expression profiling by array.
Iron-sensitive RNA regulation by poly C binding proteins [P1KD]
GEO Series GSE279951. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Downregulation of Engulfment and cell motility 1 (Elmo1) induces quiescence and resistance to poly(I:C)-induced apoptosis in endothelial cells
GEO Series GSE299038. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
mRNA expression profile in LGP2 and LGP2-4KR transgenic (Tg) HEK293 cells stimulated with short poly I:C
GEO Series GSE176363. Homo sapiens. 4 samples. Type: Expression profiling by array.
Chromatin associated RNA sequencing during the IFN response induced by poly(I:C)
GEO Series GSE109260. Homo sapiens. 8 samples. Type: Non-coding RNA profiling by high throughput sequencing.
RNA-seq analysis of growth factor response of NHEKs to antimicrobial petide LL-37 and dsRNA mimic Poly(I:C)
GEO Series GSE79343. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Poly(A) Tail Length of L4 C. elegans
GEO Series GSE104501. Caenorhabditis elegans. 2 samples. Type: Expression profiling by high throughput sequencing; Other.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
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