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22 results for “Pathways of transmission”
Fig. 5 in Heartworm and seal louse: Trends in prevalence, characterisation of impact and transmission pathways in a unique parasite assembly on seals in the North and Baltic Sea
Fig. 5. Scanning electron microscopic images of E. horridus attached to seal skin and fur. A: E. horridus utilizing a hair follicle of harbour seal skin. B: E. horridus attached to seal hair with the head pointing towards seal skin. C: E. horridus with six claws attached to seal fur. D: Close up of an unattached claw of E. horridus. Asterisks positioned on nits of E. horridus. Sale bars: A 200 μm, B 400 μm, C 400 μm, D 100 μm.
Fig. 4 in Heartworm and seal louse: Trends in prevalence, characterisation of impact and transmission pathways in a unique parasite assembly on seals in the North and Baltic Sea
Fig. 4. Histological sections and staining of E. horridus revealing filarial stages in E. horridus. A: Filarial stages (arrowheads) in the pharynx. bar = 20 μm. B: Filarial stage (arrow) in the mouth region. bar = 40 μm. C: Filarial stage (arrowhead) in the intestine (in) surrounded by erythrocytes (e). bar = 15 μm. D: Filarial stage in the haemocoel (hc) of the abdomen of E. horridus (square). E: Close up of filarial stage. mp = mouthparts, mo = mouth, cu = cuticula. A–C: Haematoxylin - Eosin stain, D: Giemsa stain.
Fig. 3. A in Heartworm and seal louse: Trends in prevalence, characterisation of impact and transmission pathways in a unique parasite assembly on seals in the North and Baltic Sea
Fig. 3. A: Prevalence of A. spirocauda and E. horridus in harbour seals in the North and Baltic Sea from 1996 to 2021, data from 1996 to 2013 according to Lehnert et al. (2016). B: Prevalence of A. spirocauda and E. horridus in harbour seals during the seasons in the North and Baltic Sea from 2014 to 2021.
Fig. 2 in Heartworm and seal louse: Trends in prevalence, characterisation of impact and transmission pathways in a unique parasite assembly on seals in the North and Baltic Sea
Fig. 2. Sampling routine of E. horridus infected seal skin for histological and bacteriological examinations. A: Mild E. horridus infection of a harbour seal yearling, asterisk pointing at E. horridus. B: Close up of E. horridus C: Removing of E. horridus D: Cutting and removing of the infected skin with a sterile forceps for further investigations. Scale bars: A-D 1 cm.
Fig. 1 in Heartworm and seal louse: Trends in prevalence, characterisation of impact and transmission pathways in a unique parasite assembly on seals in the North and Baltic Sea
Fig. 1. Levels of infection with E. horridus in P. vitulina. A: Mild E. horridus infection of a harbour seal yearling, asterisk pointing at E. horridus B: Close up of E. horridus in the head area of a harbour seal C: Severe E. horridus infection of a harbour seal D: Close up of severe E. horridus infection. Scale bars: A-D 1 cm.
Data from: Transmission pathways and spillover of an erythrocytic bacterial pathogen from domestic cats to wild felids
Many pathogens infect multiple hosts, and spillover from domestic to wild species poses a significant risk for spread of diseases that threaten wildlife and humans. Documentation of cross-species transmission, and unravelling the mechanisms that drive it, remains a challenge. Focusing on co-occurring domestic and wild felids, we evaluate possible transmission mechanisms and evidence of spillover of 'Candidatus Mycoplasma haemominutum' (CMhm), an erythrocytic bacterial parasite of cats. We examine transmission and possibility of spillover by analysing CMhm prevalence, modeling possible transmission pathways, deducing genotypes of CMhm pathogens infecting felid hosts based on sequences of the bacterial 16S rRNA gene, and conducting phylogenetic analyses with ancestral state reconstruction to identify likely cross-species transmission events. Model selection analyses suggest both indirect (i.e., spread via vectors) and direct (i.e., via inter-specific predation) pathways may play a role in CMhm transmission. Phylogenetic analyses indicate that transmission of CMhm appears to predominate within host species, with occasional spillover, at unknown frequency, between species. These analyses are consistent with transmission by predation of smaller cats by larger species, with subsequent within-species persistence after spillover. Our results implicate domestic cats as a source of global dispersal and spillover to wild felids via predation. We contribute to the emerging documentation of predation as a common means of pathogen spillover from domestic to wild cats, including pathogens of global conservation significance. These findings suggest risks for top predators as bioaccumulators of pathogens from subordinate species.
Data from: Transmission pathways and spillover of an erythrocytic bacterial pathogen from domestic cats to wild felids
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Data from: IL-13 and IL-17A activate β1 integrin through an NF-kB/Rho kinase/PIP5K1γ pathway to enhance force transmission in airway smooth muscle
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Data from: Pathways of information transmission amongst wild songbirds follow experimentally imposed changes in social foraging structure
Animals regularly use information from others to shape their decisions. Yet, determining how changes in social structure affect information flow and social learning strategies has remained challenging. We manipulated the social structure of a large community of wild songbirds by controlling which individuals could feed together at automated feeding stations (selective feeders). We then provided novel ephemeral food patches freely accessible to all birds and recorded the spread of this new information. We demonstrate that the discovery of new food patches followed the experimentally imposed social structure and that birds disproportionately learnt from those whom they could forage with at the selective feeders. The selective feeders reduced the number of conspecific information sources available and birds subsequently increased their use of information provided by heterospecifics. Our study demonstrates that changes to social systems carry over into pathways of information transfer and that individuals learn from tutors that provide relevant information in other contexts.
Data from: Pathways of information transmission amongst wild songbirds follow experimentally imposed changes in social foraging structure
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Inter-organ transmission of hepatocellular senescence induces multi-organ dysfunction through the TGFbeta signalling pathway
GEO Series GSE267196. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Inter-organ transmission of hepatocellular senescence induces multi-organ dysfunction through the TGFβ signalling pathway.
GEO Series GSE262705. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance
GEO Series GSE117748. Human alphaherpesvirus 2; JC polyomavirus; Betapolyomavirus hominis; Human immunodeficiency virus 1; Human alphaherpesvirus 1; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae; Homo sapiens; Rhadinovirus; Merkel cell polyomavirus. 75 samples. Type: Expression profiling by array; Expression profiling by high throughput sequencing; Non-coding RNA profiling by array; Non-coding RNA profiling by high throughput sequencing.
Data for research paper: Social transmission along multiple pathways promotes information fidelity and reduces divisiveness
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Investigation of the Transmission Pathways of Reflux in Patients With Chronic Venous Insufficiency
ClinicalTrials.gov study NCT06369207. IPD Sharing: Not stated. Countries: 1. Publications: 0.
MicroRNA-mediated suppression of the TGF-ß pathway confers transmissible and reversible CDK4/6 inhibitor resistance (miRNA array)
GEO Series GSE117745. Human alphaherpesvirus 2; Lymphocryptovirus; Homo sapiens; Human alphaherpesvirus 1; Rhadinovirus; Betapolyomavirus hominis; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Cytomegalovirus; Betapolyomavirus macacae. 9 samples. Type: Non-coding RNA profiling by array.
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (array I)
GEO Series GSE117742. Homo sapiens. 6 samples. Type: Expression profiling by array.
Expression Profiling of Extracellular Microvesicles Reveals Intercellular Transmission of Oncogenic Pathways
GEO Series GSE78718. Homo sapiens. 10 samples. Type: Expression profiling by array.
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (array II)
GEO Series GSE117743. Homo sapiens. 9 samples. Type: Expression profiling by array.
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq)
GEO Series GSE117746. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.