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246 results for “ROS”
Dataset Rodríguez-Ros et al. 2020 / Isoprene in the Southern Ocean - ISOREMS model
<p>Dataset of isoprene measurements in the Southern Ocean for the manuscript submitted to the Journal <em>Atmosphere</em>. </p> <p>Rodríguez-Ros et al. 2020 (Submitted):</p> <p><em>Distribution and drivers of marine isoprene concentration across the Southern Ocean</em></p> <p><em>%%%%%%<br> Variables' names contained in "isorems_data.csv"<br> %%%%%%</em></p> <p><em>"id" = source of the data ("peg" = PEGASO cruise, "ace" = ACE Expedition, "pml" = ANDREXII, "ooki" = Ooki et al. 2015, "hack" = Hackemberg et al. 2017)</em></p> <p><em>"solar_time" = solar time estimated with solaR package on R.</em></p> <p><em>"iso_pm" = Isoprene concentration (pM)</em></p> <p><em>"chla_fluo" = Chlorophyll-a (fluorometric)</em></p> <p><em>"chla_matchup" = Chlorophyll-a (MODIS Aqua)</em></p> <p><em>"sst_matchup" = Sea Surface Temperature (MODIS Aqua)</em></p> <p><em>"zeu_matchup" = Depth of the Euphotic Layer (MODIS Aqua)</em></p> <p><em>"poc_matchup" = Particulate Organic Carbon (MODIS Aqua)</em></p> <p><em>"pic_matchup" = Particulate Inorganic Carbon (MODIS Aqua)</em></p> <p><em>"mld_matchup" = Mixing Layer Depth (Holte et al. 2017)</em></p> <p><em>"par_matchup" = PAR radiation (MODIS Aqua)</em></p> <p><em>"lat" = Latitude (decimal degrees)</em></p> <p><em>"lon" = Longitude (decimal degrees)</em></p>
Image quantification data for: Activity-dependent mitochondrial ROS signaling regulates recruitment of glutamate receptors to synapses
<p>Our understanding of mitochondrial signaling in the nervous system has been limited by the technical challenge of analyzing mitochondrial function <em>in vivo</em>. In the transparent genetic model <em>Caenorhabditis elegans, </em>we were able to manipulate and measure mitochondrial ROS (reactive oxygen species) signaling of individual mitochondria as well as neuronal activity of single neurons <em>in vivo</em>. Using this approach, we provide evidence supporting a novel role for mitochondrial ROS signaling in dendrites of excitatory glutamatergic <em>C. elegans</em> interneurons. Specifically, we show that following neuronal activity, dendritic mitochondria take up calcium (Ca<sup>2+</sup>) via the mitochondrial Ca<sup>2+</sup> uniporter MCU-1 which results in an upregulation of mitochondrial ROS production. We also observed that mitochondria are positioned in close proximity to synaptic clusters of GLR-1, the <em>C. elegans</em> ortholog of the AMPA subtype of glutamate receptors that mediate neuronal excitation. We show that synaptic recruitment of GLR-1 is upregulated when MCU-1 function is pharmacologically or genetically impaired but is downregulated by mitoROS signaling. Thus, signaling from postsynaptic mitochondria may regulate excitatory synapse function to maintain neuronal homeostasis by preventing excitotoxicity and energy depletion.</p>
Association between Dysregulated Expression of Ca2+ and ROS-Related Gene Pairs and Breast Cancer Patient Survival
<p>This file is composed of two documents:</p> <ul> <li>Supplementary File 1 containing three Excel files with cumulative proportion survival from redox-related genes, calcium-related genes, and redox and calcium-related genes.</li> <li>Supplementary Table 3 including an Excel file with a functional enrichment analysis using redox and calcium correlated genes. Cell cycle regulation (sheet 1) and Cell adhesion and projection (sheet 2) were the biological processes more enriched.</li> </ul> <p>Both supplementary tables belongs to the study <strong>Association between Dysregulated Expression of Ca2+ and ROS-Related Gene Pairs and Breast Cancer Patient Survival</strong>, published in <strong>Molecular Diagnosis and therapy</strong></p>
Activity-dependent mitochondrial ROS signaling regulates recruitment of glutamate receptors to synapses
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ROS-specific Huntingtin Interactions: Crosslinking Optimization
<p>Optimization step in the lead up to mass spec identification of ROS-specific huntingtin protein-protein interactions.</p>
ROS-specific Huntingtin Interactions: Fractionation Optimization
<p>Optimization step in the lead up to mass spec identification of ROS-specific huntingtin protein-protein interactions.</p>
ROS-specific Huntingtin Interactions: Oxidative Stress Optimization H2O2
<p>Optimization step in the lead up to mass spec identification of ROS-specific huntingtin protein-protein interactions.</p>
ROS-Specific Huntingtin Interactions: IP Optimization in Patient-Derived Cells
<p>Optimization step in the lead up to mass spec identification of ROS-specific huntingtin protein-protein interactions.</p>
ROS-specific Huntingtin Interactions: GFP reactivation assay WT vs HD mouse striatal cells second attempt
<p>Optimization step in the lead up to phenotypic analysis of ROS-dependent huntingtin interacting proteins.</p>
ROS-specific Huntingtin Interactions: GFP reactivation assay WT vs HD mouse striatal cells
<p>Optimization step in the lead up to phenotypic analysis of ROS-dependent huntingtin interacting proteins.</p>
ROS-specific Huntingtin Interactions: GFP reactivation assay optimization in HEK 293 cells
<p>Optimization step in the lead up to phenotypic analysis of ROS-dependent huntingtin interacting proteins.</p>
ROS-specific Huntingtin Interactions: Testing inducible expression of huntingtin-specific chromobodies
<p>Testing step in the generation of an inducible system for expressing YFP-tagged huntingtin-specific intrabodies in live cells.</p>
ROS-specific Huntingtin Interactions: Cloning huntingtin-specific chromobodies into pTRE-3G
<p>Cloning step in the generation of an inducible system for expressing YFP-tagged huntingtin-specific intrabodies in live cells.</p>
ROS-specific Huntingtin Interactions: G418 kill curve in TruHD fibroblasts
<p>Optimization step in the development of an inducible system expressing YFP-tagged huntingtin-specific intrabodies for stable transfection in TruHD fibroblasts.</p>
ROS-specific Huntingtin Interactions: Comparing transfection methods for inducible expression of huntingtin-specific chromobody
<p>Optimization step in the development of an inducible system expressing YFP-tagged huntingtin-specific intrabodies for stable transfection in TruHD fibroblasts.</p>
ROS-specific Huntingtin Interactions: Inducible huntingtin-specific chromobody expression by nucleofection
<p>Optimization step in the development of an inducible system expressing YFP-tagged huntingtin-specific intrabodies for stable transfection in TruHD fibroblasts.</p>
ROS-Specific Huntingtin Interactions: ROS Source Optimization in Mouse Striatal Cells
<p>Optimization step in the lead up to mass spec identification of ROS-specific huntingtin protein-protein interactions. </p>
ROS-specific Huntingtin Interactions: GFP reactivation assay in HD patient fibroblasts
<p>Optimization step in the lead up to phenotypic analysis of ROS-dependent huntingtin interacting proteins. </p>
ROS-specific Huntingtin Interactions: In vitro poly-ADP ribose binding assays
<p>Poly-ADP ribose overlay assay with purified huntingtin protein to test ability of full-length and fragment huntingtin to bind poly-ADP ribose.</p>
ROS-Specific Huntingtin Interactions: Peptide poly ADP ribose overlay assay
<p>In vitro testing of peptides representing potential poly ADP ribose binding motifs within the huntingtin sequence.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.