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34 results for “Subfertility”
Deletion of porcine BOLL causes defective acrosomes and subfertility in Yorkshire boars
<p>This datset contains plink binaries (final_recode_ID.bed, final_recode_ID.bim, final_recode_ID.fam) that contain array-derived genotypes for 35 Yorkshire boars. 12 boars produced sperm with defective acrosomes. The case/control status (1-unaffected; 2-affected) of the 35 boars is indicated in the accompanying phenotype file (final_recode_ID.pheno).</p> <p>The corresponding pre-print is at the bioRxiv: https://biorxiv.org/cgi/content/short/2020.05.05.074724v1</p>
Reprometabolic Syndrome Mediates Subfertility in Obesity
ClinicalTrials.gov study NCT02653092. IPD Sharing: NO. Countries: 1. Publications: 2.
Why Subfertile Couples Drop Out
ClinicalTrials.gov study NCT02302781. IPD Sharing: UNDECIDED. Countries: 1. Publications: 22.
Low-dose HCG as an Adjunct to Ovarian Stimulation in Subfertile Women Undergoing ART
ClinicalTrials.gov study NCT03423537. IPD Sharing: Not stated. Countries: 1. Publications: 4.
The Potential Effects of Inofolic Plus on Abnormal Ovarian Reserve Parameters in Subfertile Women
ClinicalTrials.gov study NCT01290432. IPD Sharing: Not stated. Countries: 1. Publications: 4.
'SPRING'-Study: "Subfertility Guidelines: Patient Related Implementation in the Netherlands Among Gynaecologists"
ClinicalTrials.gov study NCT00119925. IPD Sharing: Not stated. Countries: 1. Publications: 1.
RCT on the Effect of Endometrial Injury on Ongoing Pregnancy Rate in Subfertile Women Undergoing IVF
ClinicalTrials.gov study NCT01977976. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Endometrial Scratching in Couples With Unexplained Subfertility
ClinicalTrials.gov study NCT01412606. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia
ClinicalTrials.gov study NCT07252518. IPD Sharing: NO. Countries: 1. Publications: 2.
A kaleidoscopic view of ovarian genes associated with infertility, subfertility and senescence
<p>Ovarian infertility and subfertility presenting with premature ovarian insufficiency (POI) and diminished ovarian reserve are major issues facing in the developed world due to the trend of delaying child birth. Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder affecting 6-10% of women in reproductive age. Based on advances in whole exome sequencing, evaluation of gene copy variants, together with family-based and genome-wide association studies (GWAS), we discussed genes responsible for the POI, PCOS, and ovarian senescence. We used a gene-centric approach to sort out literature deposited in the Ovarian Kaleidoscope database (http://okdb.appliedbioinfo.net) by sub-categorizing candidate genes as ligand-receptor signaling, meiosis and DNA repair, transcriptional factors, RNA metabolism, enzymes, and others. We discussed individual gene mutations found in POI patients and verification of gene functions in gene-deleted model organisms. Decreases in the expression of some of the POI genes could be responsible for early menopause, especially those essential for DNA repair and meiosis. Although multiple individual candidate gene single nucleotide polymorphisms have been analyzed in PCOS patients, only a limited number of findings have been verified and dealing with genes with known ovarian functions. We propose to set up a panel of candidate genes for targeted sequencing in POI patients and investigate ovarian expression of a set of candidate genes in PCOS patients, together with studies on mitochondria-associated genes in middle-aged subfertile patients. Continuing studies on POI and PCOS as well as ovarian senescence genes could allow better diagnosis and formulation of treatment strategies.</p>
Supplementation for Male Subfertility
ClinicalTrials.gov study NCT06091969. IPD Sharing: YES. Countries: 1. Publications: 0.
Progesterone Serum Levels in Subfertile Female Patients Undergoing in Vitro Fertilisation (IVF)
ClinicalTrials.gov study NCT01225835. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A kaleidoscopic view of ovarian genes associated with infertility, subfertility and senescence
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miRNA profiling from peripheral white blood cells in fertile and subfertile beef heifers at weaning
GEO Series GSE225854. Bos taurus. 14 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Loss of Prm1 leads to defective chromatin protamination, impaired PRM2 processing, reduced sperm motility and subfertility in male mice [PRM1]
GEO Series GSE200050. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome profiling from peripheral white blood cells in fertile and subfertile beef heifers at weaning
GEO Series GSE221903. Bos taurus. 15 samples. Type: Expression profiling by high throughput sequencing.
Serial Progesterone Level Measurements During the Menstrual Cycle in Subfertile Women
ClinicalTrials.gov study NCT05211583. IPD Sharing: NO. Countries: 1. Publications: 0.
Thyroid Function and Autoimmunity in Subfertility Women and Assisted Reproductive Therapy
ClinicalTrials.gov study NCT06394466. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Clinical Efficacy of Virtual Reality During Office Hysteroscopy and Endometrial Biopsy in Subfertility
ClinicalTrials.gov study NCT04438759. IPD Sharing: NO. Countries: 1. Publications: 0.
DNA Damage and Subfertility in Males - Lifestyle Interventions to Improve Male Fertility and Health
ClinicalTrials.gov study NCT04183374. IPD Sharing: NO. Countries: 1. Publications: 0.
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