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14 results for “Takifugu”
The genetic basis of scale-loss phenotype in the rapid radiation of Takifugu fishes
<p><b>The genetic basis of scale-loss in Takifugu pufferfishes</b></p> <p><span> </span><span><b>Abstract </b></span></p> <p>Rapid radiation associated with phenotypic divergence and convergence provides an opportunity to study the genetic mechanisms of evolution. Here we investigate the genus Takifugu that has undergone explosive radiation relatively recently and contains a subset of closely-related species with a scale-loss phenotype. By using observations during development and genetic mapping approaches, we show that the scale-loss phenotype of two Takifugu species, T. pardalis Temminck & Schlegel and T. snyderi Abe, is largely controlled by an overlapping genomic segment (QTL). A search for candidate genes underlying the scale-loss phenotype revealed that the QTL region contains no known genes responsible for the evolution of scale-loss phenotype in other fishes. These results suggest that the genes used for the scale-loss phenotypes in the two Takifugu are likely the same, but the genes used for the similar phenotype in Takifugu and distantly related fishes are not the same. Meanwhile, Fgfrl1, a gene predicted to function in a pathway known to regulate bone/scale development was identified in the QTL region. Since Fgfr1a1, another memebr of the Fgf signaling pathway, has been implicated in scale loss/scale shape in fish distantly related to Takifugu, our results suggest that the convergence of the scale-loss phenotype may be constrained by signaling modules with conserved roles in scale development.</p>
The genetic basis of scale-loss phenotype in the rapid radiation of Takifugu fishes
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Data from: Effects of 9,10-phenanthrenequione on antioxidant indices and metabolite profiles in Takifugu obscurus plasma
<p class="MDPI31text"><span><span>Derived from polycyclic aromatic hydrocarbons (PAHs), oxygenated-PAHs (oxy-PAHs) may pose hazards to </span></span><span><span>aquatic</span></span><span><span> organisms, which remains largely unknown</span></span>. <i><span><span>Takifugu obscurus</span></span></i><span><span> is an important anadromous fish species </span></span><span><span>of </span></span><span><span>high economic and ecological values. </span></span><span><span>In </span></span><span><span>t</span></span><span><span>he present study,</span></span><span><span> <i>T. obscurus</i> </span></span><span><span>was</span></span><span><span> acutely exposed to</span></span> <span><span>44.29 </span></span><span><span>μg/L</span></span><span><span> 9,10-phenanthrenequione (9,10-PQ) for 96 hours. </span></span><span><span>Change</span></span><span><span>s of antioxidant indices and metabolite profiles in plasma were compared between 9,10-PQ treatment and the control. The results showed that 9,10-PQ treatment significantly increased MDA content during 6 hours to 96 hours, increased SOD and CAT activities at 6 hours, but decreased them at 96 hours. These results indicated that 9,10-PQ induced oxidative stress to fish. </span></span><span><span>Ultra-performance liquid chromatography-mass spectrometry (UPLC-MS)</span></span><span><span> analysis revealed that four</span></span><span><span> metabolic pathways were influenced in response </span></span><span><span>to treatment with 9,10-PQ, including </span></span><span><span>glycerophospholipid metabolism</span></span><span><span>,</span></span><span><span> phenylalanine, tyrosine and tryptophan biosynthesis</span></span><span><span>,</span></span><span><span> purine metabolism and sulfur metabolism. These pathways </span></span><span>are </span><span>associated with </span><span>antioxidant mechanisms, biosynthesis of </span><span>neurotransmitters and innate immune functions. Thus, the as-obtained results confirmed that 9,10-PQ induced</span> oxidative stress and raised concerns of neurotoxicity and immunotoxicity to fish. <span>Overall, the present study posed a high environmental risk of oxy-PAHs to aquatic ecosystems. </span><span><span>Derived from polycyclic aromatic hydrocarbons (PAHs), oxygenated-PAHs (oxy-PAHs) may pose hazards to </span></span><span><span>aquatic</span></span><span><span> organisms, which remains largely unknown</span></span>. <i><span><span>Takifugu obscurus</span></span></i><span><span> is an important anadromous fish species </span></span><span><span>of </span></span><span><span>high economic and ecological values. </span></span><span><span>In </span></span><span><span>t</span></span><span><span>he present study,</span></span><span><span> <i>T. obscurus</i> </span></span><span><span>was</span></span><span><span> acutely exposed to</span></span> <span><span>44.29 </span></span><span><span>μg/L</span></span><span><span> 9,10-phenanthrenequione (9,10-PQ) for 96 hours. </span></span><span><span>Change</span></span><span><span>s of antioxidant indices and metabolite profiles in plasma were compared between 9,10-PQ treatment and the control. The results showed that 9,10-PQ treatment significantly increased MDA content during 6 hours to 96 hours, increased SOD and CAT activities at 6 hours, but decreased them at 96 hours. These results indicated that 9,10-PQ induced oxidative stress to fish. </span></span><span><span>Ultra-performance liquid chromatography-mass spectrometry (UPLC-MS)</span></span><span><span> analysis revealed that four</span></span><span><span> metabolic pathways were influenced in response </span></span><span><span>to treatment with 9,10-PQ, including </span></span><span><span>glycerophospholipid metabolism</span></span><span><span>,</span></span><span><span> phenylalanine, tyrosine and tryptophan biosynthesis</span></span><span><span>,</span></span><span><span> purine metabolism and sulfur metabolism. These pathways </span></span><span>are </span><span>associated with </span><span>antioxidant mechanisms, biosynthesis of </span><span>neurotransmitters and innate immune functions. Thus, the as-obtained results confirmed that 9,10-PQ induced</span> oxidative stress and raised concerns of neurotoxicity and immunotoxicity to fish. <span>Overall, the present study posed a high environmental risk of oxy-PAHs to aquatic ecosystems. </span></p>
Capacity for freshwater acclimation and differences in the transcription of ion transporter genes underlying different migratory life histories of Takifugu fish
<p>The genus<i> Takifugu </i>is a group of approximately 20 species of puffer fishes living in a wide range of salinity environments around East Asian countries. This group presents a broad spectrum of evolutionary stages adapted to anadromy as a result of speciation that occurred a short time (2–5 million years) ago on an evolutionary timescale. This group thus can be considered as a model for studying the evolutionary mechanisms of anadromy. We firstly conducted a transfer experiment from seawater to low-salinity waters on five <i>Takifugu</i> species: two anadromous species <i>T. obscurus</i> and <i>T. ocellatus</i>, two euryhaline wanderer marine species <i>T. rubripes</i> and <i>T. niphobles</i>, and a strictly marine species <i>T. snyderi</i>,<i> </i>and confirmed that the capacity for acclimation to hypotonic environments was associated with their life history strategies. Next, transcriptomes of the gill and intestine of these species in hypotonic condition were compared to those under hypertonic condition for each species using RNA-Sequencing so as to determine possible candidate transporters playing an important role on freshwater adaptation. As this analysis suggested that <i>cftr</i>, encoding an important ion transporter for seawater acclimation in the gill, and <i>ncc</i>, encoding a transporter that is suggested to play important osmoregulatory roles in the intestine, are important candidates, their expression was validated by quantitative real-time PCR analysis. Expression of<i> cftr</i> was downregulated in the gills of the four euryhaline species under the hypotonic condition, but no change was detected in the gill of stenohaline <i>T. snyderi</i>, which may be one reason for the poor hypotonic acclimation capacity of <i>T. snyderi</i>. Expression of <i>ncc</i> was clearly upregulated in the intestines of the two anadromous species under the hypotonic condition, but not in other three species.<b> </b>Different ion transporter expression patterns between the five species indicate that the transcriptional regulation of <i>cftr</i> in the gill and <i>ncc</i> in the intestine may be important for the improvement of hypotonic acclimation capacity and evolution of anadromy in the <i>Takifugu</i> species.</p>
Data from: The genetic architecture of growth rate in juvenile Takifugu species.
Closely related species have often evolved dramatic differences in body size. Takifugu rubripes (fugu) is a large marine pufferfish whose genome has been sequenced, whereas T. niphobles is the smallest species among Takifugu. We show that, unsurprisingly, the juvenile growth rate of T. rubripes is higher than that of T. niphobles in a laboratory setting. We produced F2 progenies of their F1 hybrids and found one quantitative trait locus (QTL) significantly associated with variation in juvenile body size. This QTL region (3.5 Mb) contains no known genes directly related to growth phenotype (such as IGFs) except Fgf21, which inhibits growth hormone signaling in mouse. The QTL in Takifugu spp. is distinct from the region previously known to control body size variations in stickleback or tilapia. Our results suggest that in the fish tested herein, genomic regions underlying body size evolution might have different genetic origins. They also suggest that many diverse traits in Takifugu spp. are amenable to genetic mapping.
Data from: The genetic architecture of growth rate in juvenile Takifugu species.
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Capacity for freshwater acclimation and differences in the transcription of ion transporter genes underlying different migratory life histories of Takifugu fish
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Data from: Effects of 9,10-phenanthrenequione on antioxidant indices and metabolite profiles in Takifugu obscurus plasma
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Deep sequencing, profiling and detailed annotation of miRNAs in Takifugu rubripes
GEO Series GSE65404. Takifugu rubripes. 9 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Spatial transcriptome analysis of brain region in grass puffer (Takifugu alboplumbeus)
GEO Series GSE186818. Takifugu alboplumbeus. 1 samples. Type: Expression profiling by high throughput sequencing.
Integrated application of multi-omics provides insights into cold stress responses in pufferfish Takifugu fasciatus
GEO Series GSE129226. Takifugu fasciatus. 6 samples. Type: Expression profiling by high throughput sequencing.
RNA-sequencing analysis of Takifugu rubripes spleen and gill in response to Vibrio harveyi infection
GEO Series GSE155911. Takifugu rubripes. 16 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide transcriptome analysis of brain region (ventral part of telenchephalon, hypothalamus and pituitary) in grass puffer (Takifugu alboplumbeus)
GEO Series GSE186499. Takifugu alboplumbeus. 24 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome analysis of the kidney of obscure puffer Takifugu obscurus challenged with poly(I:C)
GEO Series GSE181941. Takifugu obscurus. 9 samples. Type: Expression profiling by high throughput sequencing.
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