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74 results for “Thoroughness”
New calibrated models for the TRGB luminosity and a thorough analysis of theoretical uncertainties
<p>The files contain the grid models for TRGB stars based on <strong>Saltas & Tognelli, 2022, MNRAS, in press (arXiv: 2203.02499)</strong>. See the paper for details on the physics, and the attached readme file for a description of the structure of the attached files. If you use these data in your research please cite the above article. <br> </p>
Raw Data for the article: A Radioactive-Free Method for the Thorough Analysis of the Kinetics of Cell Cytotoxicity
<p>The cytotoxic activity of T cells and Natural Killer cells is usually measured with the chromium release assay (CRA), which involves the use of 51Chromium (<sup>51</sup>Cr), a radioactive substance dangerous to the operator and expensive to handle and dismiss. The accuracy of the measurements depends on how well the target cells incorporate <sup>51</sup>Cr during labelling which, in turn, depends on cellular division. Due to bystander metabolism, the target cells spontaneously release <sup>51</sup>Cr, producing a high background noise. Alternative radioactive-free methods have been developed. Here, we compare a bioluminescence (BLI)-based and a carboxyfluorescein succinimidyl ester (CFSE)-based cytotoxicity assay to the standard radioactive CRA. In the first assay, the target cells stably express the enzyme luciferase, and vitality is measured by photon emission upon the addition of the substrate d-luciferin. In the second one, the target cells are labelled with CFSE, and the signal is detected by Flow Cytometry. We used these two protocols to measure cytotoxicity induced by treatment with NK cells. The cytotoxicity of NK cells was determined by adding increasing doses of human NK cells. The results obtained with the BLI method were consistent with those obtained with the CRA- or CFSE-based assays 4 hours after adding the NK cells. Most importantly, with the BLI assay, the kinetic of NK cells' killing was thoroughly traced with multiple time point measurements, in contrast with the single time point measurement the other two methods allow, which unveiled additional information on NK cell killing pathways.</p>
Data from: Partial mycoheterotrophy in green plants forming Paris-type arbuscular mycorrhiza requires a thorough investigation
<p>Recently, many green plants forming <em>Paris</em>-type arbuscular mycorrhiza (AM) have been suggested to receive fungal carbon (Giesemann <em>et al.</em> 2020b, 2021). Whereas the enrichment of natural abundance of heavy stable isotopes (particularly <sup>13</sup>C) has been considered as strong evidence for this 'partial mycoheterotrophy,' we show our own data on isotopic abundances and mycorrhizal colonization in Japanese plants and argue that the <sup>13</sup>C-enrichment may not always be the result of acquiring carbon from AM fungi.</p>
Staccato Loxapine Thorough QT/QTc Study
ClinicalTrials.gov study NCT00874237. IPD Sharing: YES. Countries: 1. Publications: 1.
ADASUVE 2-dose Thorough QT/QTc Study
ClinicalTrials.gov study NCT01854710. IPD Sharing: NO. Countries: 1. Publications: 2.
Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects
ClinicalTrials.gov study NCT03613649. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Partial mycoheterotrophy in green plants forming Paris-type arbuscular mycorrhiza requires a thorough investigation
Open the record for dataset details and reuse information.
microbetag : building a thorough database of genome-scale KO annotations
<p>In this repository we keep internal data for the <em><a href="https://hariszaf.github.io/microbetag/">microbetag</a> </em>microbial co-occurrence network annotator.</p> <p><em>microbetag</em> makes use of 2-column files for each genome, indicating the KO term found and a KEGG module in which this terms takes part into. <br>As a single KO term might participates in more than one KEGG modules, the same KO might be more than once in an annotation file. </p> <table> <tbody> <tr> <td> <div>chem_xref.tar.gz</div> </td> <td> <p>The MNXref namespace</p> <ol> <li>The identifier of a chemical compound in an external resource [<a href="https://www.metanetx.org/mnxdoc/mnxref.html#XREF">XREF</a>]</li> <li>The corresponding identifier in the MNXref namespace [<a href="https://www.metanetx.org/mnxdoc/mnxref.html#MNX_ID">MNX_ID</a>]</li> <li>The description given by the external resource [<a href="https://www.metanetx.org/mnxdoc/mnxref.html#STRING">STRING</a>]</li> </ol> <p>MNXref 4.0 release notes: - The third column (evidence tag for the mapping) was suppressed - The descriptions were completed - Deprecated identifiers were moved into they own table below</p> </td> </tr> <tr> <td> <div>gtdb_modelseed_gems.zip</div> </td> <td> <p>for all the GTDB genomes their corresponding <a href="https://patricbrc.org/">PATRIC</a> annotations were gathered. Then, using <a href="https://github.com/ModelSEED/ModelSEEDpy">modelseedpy</a> we constructed their genome scale metabolic reconstructions</p> </td> </tr> <tr> <td> <div>gtdb_kofam_scan_per_module.tar.gz</div> </td> <td> <p>all representative genomes of <a href="https://gtdb.ecogenomic.org/">GTDB</a> (v.202) were parsed and their corresponding `.faa` files were retrieved from the <a href="https://ftp.ncbi.nlm.nih.gov/genomes/all/">NCBI FTP</a>. Then the <a href="https://github.com/takaram/kofam_scan">kofam_scan</a> tool was used to annotate them and finally a <a href="https://github.com/hariszaf/microbetag/blob/clean/mappings/gtdb_mappings/gtdb_annotations_per_module.py">manual script </a>was used to keep KOs of each genome per module. </p> </td> </tr> <tr> <td>SeedSet.pkl.gz</td> <td> <p>A pickle file with the seeds of each GEM included in the <em>gtdb_modelseed_gems.zip </em>file and related to the KEGG MODULES based on the <em>seedId_keggId_module.tsv </em>file you can find on microbetag's GitHub page. Example:</p> <p>PATRIC SeedSet<br>373.172 [cpd00891, cpd00136, cpd00199, cpd01772, cpd00...<br>397278.5 [cpd00891, cpd00136, cpd01772, cpd02698, cpd08...</p> </td> </tr> <tr> <td>NonSeedSet.pkl.gz</td> <td> <p>A pickle file with the non seeds of each GEM included in the <em>gtdb_modelseed_gems.zip </em>file and related to the KEGG MODULES based on the <em>seedId_keggId_module.tsv </em>file you can find on microbetag's GitHub page. Example:</p> <p>PATRIC NonSeedSet<br>64187.548 [cpd00508, cpd00869, cpd00774, cpd03830, cpd00...<br>74426.1719 [cpd00204, cpd00447, cpd20171, cpd03470, cpd00...</p> </td> </tr> <tr> <td>seeds_per_genome.pkl.gz</td> <td> <p>A pickle file with a binary representation of the seeds per genome . Example:</p> <p> cpd00493 cpd00296 cpd11431 cpd00063 cpd15717 ... <br>2162051.4 1 0 0 1 0 0 0 0 0 0 ... </p> </td> </tr> <tr> <td> <div>nonseeds_per_genome.pkl.gz</div> </td> <td>Like above for non-seeds.</td> </tr> <tr> <td> <div>phen_classes.zip</div> </td> <td>A list of pickle files with the re-trained classes of phenDB for the prediction of functional traits on a genome.</td> </tr> </tbody> </table> <p> </p> <p> </p> <p> </p> <p> </p>
Subspecies and Distribution. P.h.hesperidusTemminck,1840—EAfricainEritrea,Djibouti,Ethiopia,SWSudan,SouthSudan,andNE&SSomalia. P.h.fuscatusThomas,1901—EAfricainEDRCongo,Uganda,Kenya,Rwanda,Burundi,andTanzania. P. h. subtilis Sundevall, 1846 — S Africa in NC, C & W Angola, Zambia, Malawi, Mozambique, Zimbabwe, NC Botswana, E & South Africa, Swaziland, Lesotho, and along the W coast of Madagascar. There are also records on Canary and Cape Verde Is and in W Africa in W & SE Senegal, N Liberia, SE Ivory Coast, SC Burkina Faso, SE Ghana, SW Niger, NC Nigeria, W Cameroon, and Bioko I, although exact placement of these populations among taxa currently recognized under the P. hesperidus species complex is uncertain. A thorough investigation of records of this species is needed. in Vespertilionidae
Subspecies and Distribution. P.h.hesperidusTemminck,1840—EAfricainEritrea,Djibouti,Ethiopia,SWSudan,SouthSudan,andNE&SSomalia. P.h.fuscatusThomas,1901—EAfricainEDRCongo,Uganda,Kenya,Rwanda,Burundi,andTanzania. P. h. subtilis Sundevall, 1846 — S Africa in NC, C & W Angola, Zambia, Malawi, Mozambique, Zimbabwe, NC Botswana, E & South Africa, Swaziland, Lesotho, and along the W coast of Madagascar. There are also records on Canary and Cape Verde Is and in W Africa in W & SE Senegal, N Liberia, SE Ivory Coast, SC Burkina Faso, SE Ghana, SW Niger, NC Nigeria, W Cameroon, and Bioko I, although exact placement of these populations among taxa currently recognized under the P. hesperidus species complex is uncertain. A thorough investigation of records of this species is needed.
A Thorough QTc Trial Evaluating the Effect of SNAC on Cardiac Repolarisation in Healthy Male Subjects.
ClinicalTrials.gov study NCT02911870. IPD Sharing: YES. Countries: 1. Publications: 1.
A Thorough QTc Evaluation of the Effect of Semaglutide on Cardiac Repolarisation in Healthy Subjects
ClinicalTrials.gov study NCT02064348. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Thorough QT Study of TR-701free Acid (FA) in Healthy Subjects
ClinicalTrials.gov study NCT01461460. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Sativex Thorough QT/QTc Study
ClinicalTrials.gov study NCT01322139. IPD Sharing: Not stated. Countries: 1. Publications: 1.
BNP Measurement Reduces Resource Utilization for Patients With CHF Admitted Thorough the ED
ClinicalTrials.gov study NCT00587938. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Figures 7-13 from: Hopkins T, Roininen H, van Noort S, Broad GR, Kaunisto K, Sääksjärvi IE (2019) Extensive sampling and thorough taxonomic assessment of Afrotropical Rhyssinae (Hymenoptera, Ichneumonidae) reveals two new species and demonstrates the limitations of previous sampling efforts. ZooKeys 878: 33-71. https://doi.org/10.3897/zookeys.878.37845
Figures 7-13 Epirhyssa ghesquierei female (http://mus.utu.fi/ZMUT.5853), a species found in Uganda. 7 Habitus 8 face and clypeus 9 frons 10 hypostomal flange 11 mesopleuron dorsal margin 12 apical horn of metasoma 13 tergites 1–7. Scale bars: 0.5 mm (8–13), 1 mm (7).
Figures 68-71 from: Hopkins T, Roininen H, van Noort S, Broad GR, Kaunisto K, Sääksjärvi IE (2019) Extensive sampling and thorough taxonomic assessment of Afrotropical Rhyssinae (Hymenoptera, Ichneumonidae) reveals two new species and demonstrates the limitations of previous sampling efforts. ZooKeys 878: 33-71. https://doi.org/10.3897/zookeys.878.37845
Figures 68-71 Epirhyssa villemantae female (holotype). This species was not found in Uganda. 68 Habitus 69 hypostomal flange 70 mesopleuron dorsal margin 71 apical horn of metasoma. Figure 68 is from van Noort (2019).
Figures 72-75 from: Hopkins T, Roininen H, van Noort S, Broad GR, Kaunisto K, Sääksjärvi IE (2019) Extensive sampling and thorough taxonomic assessment of Afrotropical Rhyssinae (Hymenoptera, Ichneumonidae) reveals two new species and demonstrates the limitations of previous sampling efforts. ZooKeys 878: 33-71. https://doi.org/10.3897/zookeys.878.37845
Figures 72-75 Megarhyssa babaulti female (holotype). This species was not found in Uganda. 72 Habitus 73 mesopleuron dorsal margin 74 hypostomal flange 75 apical horn of metasoma. Figure 72 is from van Noort (2019), 73–75 courtesy of MNHN (Agnièle Touret-Alby).
Figures 64-67 from: Hopkins T, Roininen H, van Noort S, Broad GR, Kaunisto K, Sääksjärvi IE (2019) Extensive sampling and thorough taxonomic assessment of Afrotropical Rhyssinae (Hymenoptera, Ichneumonidae) reveals two new species and demonstrates the limitations of previous sampling efforts. ZooKeys 878: 33-71. https://doi.org/10.3897/zookeys.878.37845
Figures 64-67 Epirhyssa gavinbroadi female (holotype). We treat this species as a synonym of E. uelensis in this work. 64 Habitus 65 hypostomal flange 66 mesopleuron dorsal margin 67 apical horn of metasoma. Figure 64 is from van Noort (2019).
Figures 57-63 from: Hopkins T, Roininen H, van Noort S, Broad GR, Kaunisto K, Sääksjärvi IE (2019) Extensive sampling and thorough taxonomic assessment of Afrotropical Rhyssinae (Hymenoptera, Ichneumonidae) reveals two new species and demonstrates the limitations of previous sampling efforts. ZooKeys 878: 33-71. https://doi.org/10.3897/zookeys.878.37845
Figures 57-63 Epirhyssa uelensis female (http://mus.utu.fi/ZMUT.2520), a species found in Uganda. 57 Habitus 58 face and clypeus 59 frons 60 hypostomal flange 61 mesopleuron dorsal margin 62 apical horn of metasoma 63 tergites 1–7. Scale bars: 0.5 mm (58–63), 1 mm (57).
Figures 50-56 from: Hopkins T, Roininen H, van Noort S, Broad GR, Kaunisto K, Sääksjärvi IE (2019) Extensive sampling and thorough taxonomic assessment of Afrotropical Rhyssinae (Hymenoptera, Ichneumonidae) reveals two new species and demonstrates the limitations of previous sampling efforts. ZooKeys 878: 33-71. https://doi.org/10.3897/zookeys.878.37845
Figures 50-56 Epirhyssa tombeaodiba female (http://mus.utu.fi/ZMUT.5663, 52: http://mus.utu.fi/ZMUT.3234), a species found in Uganda. 50 Habitus 51 face and clypeus 52 frons 53 hypostomal flange 54 mesopleuron dorsal margin 55 apical horn of metasoma 56 tergites 1–7. Scale bars: 0.5 mm (51–56), 1 mm (50).
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.