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11 results for “UV filter”
New Generation UV-A Filters: Understanding Their Photodynamics on a Human Skin Mimic
<p>The sparsity of efficient commercial ultraviolet-A (UV-A) filters is a major challenge towards developing effective broadband sunscreens with minimal human- and eco-toxicity. To combat this, we have designed a new class of Meldrum-based phenolic UV-A filters. We explore the ultrafast photodynamics of coumaryl Meldrum, CMe, and sinapyl Meldrum, SMe, both in an industry standard emollient and on a synthetic skin mimic, using femtosecond transient electronic and vibrational absorption spectroscopies, and computational simulations. Upon photoexcitation to the lowest excited singlet state (S<sub>1</sub>), these Meldrum-based phenolics undergo fast and efficient non-radiative decay to repopulate the electronic ground state (S<sub>0</sub>). We propose an initial ultrafast twisted intramolecular charge transfer mechanism as these systems evolve out of the Franck-Condon region towards an S<sub>1</sub>/S<sub>0</sub> conical intersection, followed by internal conversion to S<sub>0</sub> and subsequent vibrational cooling. Importantly, we correlate these findings to their long-term photostability upon irradiation with a solar simulator and conclude that these molecules surpass the basic requirements of an industry standard UV filter.</p>
Data for: Are UV filters better together? A comparison of the toxicity of individual ultraviolet filters and off-the-shelf sunscreens to Daphnia magna
Open the record for dataset details and reuse information.
Biomarker responses of the blue mussels to organic UV filters
<p>This is the metadata for the publication: <strong>Falfushynska, H., Sokolov, E. P., Fisch, K., Gazie, H., Schulz-Bull, D. E. and Sokolova, I. M.</strong> (2021). Biomarker-based assessment of sublethal toxicity of organic UV filters (ensulizole and octocrylene) in a sentinel marine bivalve Mytilus edulis. <em>Science of The Total Environment</em> <strong>798</strong>, 149171. DOI: <a href="https://doi.org/10.1016/j.scitotenv.2021.149171">10.1016/j.scitotenv.2021.149171</a></p>
MED in UVB Devices in the Presence and Absence of UV Filter
ClinicalTrials.gov study NCT03049319. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Insights into the photoprotection mechanism of the UV filter homosalate
<p>Homosalate (HMS) is a salicylate molecule that is commonly included within commercial sunscreen formulations to provide protection from the adverse effects of ultraviolet (UV) radiation exposure. In the present work, the mechanisms by which HMS provides UV photoprotection are unravelled, using a multi-pronged approach involving a combination of time-resolved ultrafast laser spectroscopy in the gas-phase and in solution, laser-induced fluorescence, steady-state absorption spectroscopy, and computational methods. The unique combination of these techniques allow us to show that the <em>enol</em> tautomer of HMS undergoes ultrafast excited state intramolecular proton transfer (ESIPT) upon photoexcitation in the UVB (290–320 nm) region; once in the <em>keto</em> tautomer, the excess energy is predominantly dissipated non-radiatively. Sharp transitions are observed in the LIF spectrum at close-to-origin excitation energies, which points towards the potential presence of a second conformer that does not undergo ESIPT. These studies demonstrate that, overall, HMS exhibits mostly favourable photophysical characteristics of a UV filter for inclusion in sunscreen formulations.</p>
Wavepacket insights into the photoprotection mechanism of the UV filter methyl anthranilate
<p>Geometries of the S<sub>0,eq </sub>(S0_geom.csv), S<sub>1,eq</sub> (S1_geom.csv), and D<sup>+</sup><sub>0,eq</sub> (D0+_geom.csv) states of MA contain atom labels (<em>e.g.</em> C) and Cartesian coordinates in four columns; distances are in Angstroms (Å).</p> <p>All TR-PES transients are formatted as comma separated variable text files: each column is the photoelectron intensity at one time delay (labeled in the first row) with one eKE value per row (labeled in the first column). Files are labeled with the molecule, pump wavelength, probe wavelength, and a date (<em>e.g</em>. MA_344_285_18June2018.csv).</p> <p>The MATLAB code used to calculate the wavepacket “transients” is also contained herein as wavepacket.m. The code takes user inputs such as the Franck-Condon factors and laser pulse spectral characteristics.</p> <p>The LIF spectrum of photoexcited MA (MA_LIF.csv) is also presented as two columns: pump photon energy and LIF intensity.</p>
UV filter ecotoxicity data
<p>Acute and chronic exotoxicity data of organic UV-filter substances currently allowed in the EU.</p>
Validation of Senofilcon A With New UV / HEV Filter
ClinicalTrials.gov study NCT05099380. IPD Sharing: YES. Countries: 1. Publications: 0.
Toxicity mechanisms of ZnO UV-filters used in sunscreens toward the model cyanobacteria Synechococcus elongatus PCC7942
GEO Series GSE102914. Synechococcus elongatus PCC 7942 = FACHB-805. 16 samples. Type: Expression profiling by array.
Bemotrizinol UV Filter Part 1 Clinical PK Evaluation in Topical MUsT Study
ClinicalTrials.gov study NCT04355286. IPD Sharing: NO. Countries: 1. Publications: 0.
Data for effects of UV filters on coral thermal tolerance
<p>Data for effects of UV filters on coral thermal tolerance</p>
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International Brain Laboratory public data
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OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.