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15
datasets available to search
ShareScore release 0.9.0
Dataset results
15 results for “adrenal androgens”
Androgen Reduction in Congenital Adrenal Hyperplasia, Phase 1
ClinicalTrials.gov study NCT02574910. IPD Sharing: YES. Countries: 1. Publications: 1.
Effects of Adrenal Androgens on Gender-typed Behavior in Girls With Turner Syndrome
ClinicalTrials.gov study NCT05346159. IPD Sharing: UNDECIDED. Countries: 1. Publications: 7.
Androgen Reduction in Congenital Adrenal Hyperplasia
ClinicalTrials.gov study NCT03548246. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Evaluation of Serum Adrenal Androgens Among Prepubertal and Pubertal Boys With Autism Spectrum Disorder
ClinicalTrials.gov study NCT05811507. IPD Sharing: YES. Countries: 1. Publications: 4.
Data from: The agonistic adrenal: melatonin elicits female aggression via regulation of adrenal androgens
Classic findings have demonstrated an important role for sex steroids as regulators of aggression, but this relationship is lacking within some environmental contexts. In mammals and birds, the adrenal androgen dehydroepiandrosterone (DHEA), a non-gonadal precursor of biologically active steroids, has been linked to aggression. Although females, like males, use aggression when competing for limited resources, the mechanisms underlying female aggression remain understudied. Here, we propose a previously undescribed endocrine mechanism regulating female aggression via direct action of the pineal hormone melatonin on adrenal androgens. We examined this in a solitary hamster species, Phodopus sungorus, in which both sexes are highly territorial across the seasons, and display increased aggression concomitant with decreased serum levels of sex steroids in short "winter-like" days. Short- but not long-day females had increased adrenal DHEA responsiveness co-occurring with morphological changes in the adrenal gland. Further, serum DHEA and total adrenal DHEA content were elevated in short days. Lastly, melatonin increased DHEA and aggression and stimulated DHEA release from cultured adrenals. Collectively, these findings demonstrate that DHEA is a key peripheral regulator of aggression and that melatonin coordinates a "seasonal switch" from gonadal to adrenal regulation of aggression by direct action on the adrenal glands.
The Adrenal Contribution to Androgen Production in Girls During Puberty
ClinicalTrials.gov study NCT01062568. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens
ClinicalTrials.gov study NCT05370521. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: The agonistic adrenal: melatonin elicits female aggression via regulation of adrenal androgens
Open the record for dataset details and reuse information.
An integrated RNA-Seq and network study reveals the effect of nicotinamide on adrenal androgen synthesis
GEO Series GSE161730. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess
ClinicalTrials.gov study NCT01422759. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Longer-term Adrenal Suppression Using Low Dose Hydrocortisone on Androgen Overproduction
ClinicalTrials.gov study NCT01422733. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess
ClinicalTrials.gov study NCT01422746. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess
ClinicalTrials.gov study NCT01422707. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of Adrenal Androgens in Normal and Obese Girls After Suppression and Stimulation
ClinicalTrials.gov study NCT01421797. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The transcription factor HHEX and the Androgen receptor (AR) drive the mouse adrenal sexual dimorphism
GEO Series GSE291344. Mus musculus. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.