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23
datasets available to search
ShareScore release 0.9.0
Dataset results
23 results for “antiviral resistance”
Antiviral activity of HIV-1 integrase strand-transfer inhibitors against mutants with integrase resistance-associated mutations and their frequency in treatment-naïve individuals
<p>The development of resistance to human immunodeficiency virus 1 (HIV-1) integrase strand-transfer inhibitors (INSTI) has been documented; however, knowledge of the impact of pre-existing integrase (IN) mutations on INSTI resistance (INSTI-R) is still evolving. The frequency of HIV-1 IN mutations in 2177 treatment-naïve subjects was investigated, along with the INSTI susceptibility of site-directed mutant viruses containing major and minor INSTI-R mutations. Total 6 of 39 minor INSTI-R mutations (M50I, S119P/G/T/R, and E157Q) were found in >1% of IN-treatment-naïve subjects with no impact on INSTI susceptibility. When each combined with major INSTI-R mutation, M50I, S119P, and E157Q led to decreased susceptibility to elvitegravir but remained sensitive to dolutegravir and bictegravir.</p>
Antiviral Activity of and Resistance to Lamivudine in Combination With Zidovudine, Stavudine, or Didanosine
ClinicalTrials.gov study NCT00000838. IPD Sharing: Not stated. Countries: 2. Publications: 3.
Hepatitis C Antiviral Resistance in African-Americans
ClinicalTrials.gov study NCT00038974. IPD Sharing: YES. Countries: 1. Publications: 5.
Treating Hepatitis C in Pakistan. Strategies to Avoid Resistance to Antiviral Drugs
ClinicalTrials.gov study NCT04943588. IPD Sharing: NO. Countries: 1. Publications: 9.
An Observational Study on Long-Term Persistence of Resistant Mutations And Durability of Sustained Virological Response in Patients With Chronic Hepatitis C Treated With Direct Acting Antiviral (DAA)-
ClinicalTrials.gov study NCT01168856. IPD Sharing: Not stated. Countries: 15. Publications: 0.
The antiviral nuclear body protein SP140 represses Ifnb1 transcript stabilization by the novel regulator RESIST [RNA-seq]
GEO Series GSE269761. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
The Antiviral Small-Interfering RNA Pathway Induces Zika Virus Resistance in Transgenic Aedes aegypti
GEO Series GSE156825. Aedes aegypti. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.
BCG vaccination stimulates Integrated Organ Immunity by feedback of the adaptive immune response to imprint prolonged innate antiviral resistance
GEO Series GSE244126. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
sRNA sequencing to study assorted processing of synthetic trans-acting siRNAs and its activity in antiviral resistance
GEO Series GSE69348. Nicotiana benthamiana. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Safety and Antiviral Study of ACH126, 433 (b-L-Fd4C) in Adults With Lamivudine-resistant Chronic Hepatitis B
ClinicalTrials.gov study NCT00040144. IPD Sharing: Not stated. Countries: 3. Publications: 0.
The Durability of Response and Persistence of Resistance to AbbVie's 2 Direct-acting Antiviral Agent (2D) Therapy in Japanese Subjects
ClinicalTrials.gov study NCT02581020. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
A French Cohort of Transplant Recipients With CMV Infection : Risk Factors for Antiviral Resistance in the Prophylaxis Era.
ClinicalTrials.gov study NCT02067169. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Changes in Liver Fibrosis, Lipid Profile and Insulin Resistance in HCV Patients Who Received Antiviral Therapy
ClinicalTrials.gov study NCT03612973. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study to Assess the Antiviral Activity and Safety Endpoints for the Treatment of Besifovir 150mg Compared to Tenofovir 300mg in Chronic Hepatitis B Patients Who Have Resistance to Nucleoside Analogues
ClinicalTrials.gov study NCT02792088. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Insulin Resistance Associated With Chronic Hepatitis C (CHC) and the Effect of Antiviral Therapy
ClinicalTrials.gov study NCT00188240. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Surveillance for Antiviral Resistant Variants in Chronic Hepatitis C Patients
ClinicalTrials.gov study NCT02065999. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The antiviral nuclear body protein SP140 represses Ifnb1 transcript stabilization by the novel regulator RESIST [WT and SP140 KO RNA-seq]
GEO Series GSE269808. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
The antiviral nuclear body protein SP140 represses Ifnb1 transcript stabilization by the novel regulator RESIST
GEO Series GSE269315. Mus musculus. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
BCG vaccination stimulates Integrated Organ Immunity by feedback of the adaptive immune response to imprint prolonged innate antiviral resistance [GeoMx]
GEO Series GSE247145. Mus musculus. 106 samples. Type: Expression profiling by high throughput sequencing; Other.
The antiviral nuclear body protein SP140 represses Ifnb1 transcript stabilization by the novel regulator RESIST [ATAC-seq]
GEO Series GSE269811. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.