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59 results for “blood groups”
A Dose Escalation Study of a Combination Antihypertensive Drug in the Treatment of Various Groups of Patients Who do Not Respond to Single Drug Treatment of Their High Blood Pressure
ClinicalTrials.gov study NCT00791258. IPD Sharing: YES. Countries: 1. Publications: 2.
Pragmatic Prehospital Group O Whole Blood Early Resuscitation Trial
ClinicalTrials.gov study NCT03477006. IPD Sharing: NO. Countries: 1. Publications: 2.
Data from: Haplotype sequence collection of ABO blood group alleles by long-read sequencing reveals putative A1-diagnostic variants
<p>In the era of blood group genomics, reference collections of complete and fully-resolved blood group gene alleles have gained high importance. For most blood groups, however, such collections are currently lacking, as resolving full-length gene sequences as haplotypes (i.e. separated maternal/paternal origin) remains exceedingly difficult with both Sanger and short-read next-generation sequencing. Using the latest third-generation long-read sequencing, we generated a collection of fully-resolved sequences for all six main <em>ABO</em> allele groups: <em>ABO</em>*<em>A1</em>/<em>A2</em>/<em>B</em>/<em>O.01.01</em>/<em>O.01.02</em>/<em>O.02</em>. We selected 77 samples from an <em>ABO</em> genotype dataset (n=25,200) of serologically-typed Swiss blood donors. The entire <em>ABO</em> gene was amplified in two overlapping long-range PCRs (covering ~23.6 kb) and sequenced by long-read Oxford Nanopore sequencing. For quality validation, two samples per <em>ABO</em> group were re-sequenced using Illumina and PacBio technology. All 154 full-length <em>ABO</em> sequences were resolved as haplotypes. We observed novel, distinct sequence patterns for each <em>ABO</em> group. Most genetic diversity was found between, not within, <em>ABO</em> groups. Phylogenetic tree and haplotype network analyses highlighted distinct clades of each <em>ABO</em> group. Strikingly, our data uncovered four genetic variants putatively specific for <em>ABO</em>*<em>A1</em>, for which direct diagnostic targets are currently lacking. We validated <em>A1</em>-diagnostic potential using whole-genome data (n=4,872) of a multi-ethnic cohort. Overall, our sequencing strategy proved powerful for producing high-quality <em>ABO</em> haplotypes and holds promise for generating similar collections for other blood groups. The publicly available collection of 154 haplotypes will serve as a valuable resource for molecular analyses of <em>ABO</em>, as well as studies about the function and evolutionary history of <em>ABO</em>.</p>
Our simulated cerebral blood flow changed from pretreatment to posttreatment status between rehabilitation (see video 1, supplemental data) and ILIB groups (see video 2, supplemental data).
<p>Our simulated cerebral blood flow changed from pretreatment to posttreatment status between rehabilitation (see video 1, supplemental data) and ILIB groups (see video 2, supplemental data).</p> <p>Video S1 demonstrates that the cerebral blood flow changed from pretreatment to posttreatment status in one participant of rehabilitation.</p> <p>Video S2 demonstrates that the cerebral blood flow changed from pretreatment to posttreatment status in one participant of ILIB.</p>
Trauma Resuscitation With Low-Titer Group O Whole Blood or Products
ClinicalTrials.gov study NCT05638581. IPD Sharing: NO. Countries: 1. Publications: 2.
ABO Blood Group Antibody Elimination by a Combination of Semiselective Immunoadsorption Therapy and Membrane Filtration
ClinicalTrials.gov study NCT01698736. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ABO Blood Group Type Association With COVID-19 Severity
ClinicalTrials.gov study NCT05859958. IPD Sharing: NO. Countries: 1. Publications: 4.
Susceptibility of Human Volunteers With Different Histo-Blood With Different Histo-Blood Group Antigens to Norovirus
ClinicalTrials.gov study NCT01322503. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Influence of ABO Blood Group on the Risk of Complications in Alcoholic or Viral C Cirrhosis?
ClinicalTrials.gov study NCT03342170. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Assessment of Response to the Conventional Periodontal Treatment Based on the Blood Group Phenotypes.
ClinicalTrials.gov study NCT03644901. IPD Sharing: NO. Countries: 1. Publications: 5.
Data from: Haplotype sequence collection of ABO blood group alleles by long-read sequencing reveals putative A1-diagnostic variants
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DISTINCTIONS BETWEEN BIOCHEMICAL INDICATORS OF DIFFERENT BLOOD GROUPS
<p>The purpose of this work is to evaluate the differences in some biochemical parameters in blood plasma of blood groups I (0), II (A), III (B) and IV (AB). Biochemical indicators were determined on a Humastar100 (Germany) biochemical analyzer. The obtained results showed that there are certain statistically reliable differences between the amounts of biochemical indicators such as albumin, glucose, cholesterol, triglyceride and urea in blood plasmas of different blood groups.</p>
Raw Data of CCHF-Blood Group Study
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Analysis of Data Collected in the European Group for Blood and Marrow Transplantation (EBMT) Registry on a Cohort of Patients Receiving Plerixafor
ClinicalTrials.gov study NCT01362972. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Evaluation of Echocardiographic Indices and Blood Biomarkers in Group 1 Pulmonary Hypertension
ClinicalTrials.gov study NCT04279145. IPD Sharing: Not stated. Countries: 0. Publications: 7.
Eculizumab to Prevent Antibody-mediated Rejection in ABO Blood Group Incompatible Living Donor Kidney Transplantation
ClinicalTrials.gov study NCT01095887. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study of the Relationship Between Blood Groups,RH and Skeletal Malocclusion : a Cross Sectional Study
ClinicalTrials.gov study NCT03085082. IPD Sharing: NO. Countries: 0. Publications: 1.
Association of ABO blood groups with presentation and outcomes of confirmed SARS CoV-2 infection: A prospective study in the largest COVID-19 dedicated hospital in Bangladesh
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Exploration of specific gene expression behind the intercellular heterogeneity of type 2 cytokine secretion activity of Group 2 innate lymphoid cell (ILC2) isolated from peripheral blood of severe ast
GEO Series GSE213810. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Single-cell gene expression profile of primary human peripheral blood natural killer cells grouped into seven phenotypically-defined populations
GEO Series GSE243030. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.