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307 results for “cardiovascular risk factors”
Prevalence and determinants of cardiovascular risk factors in Lesotho: a population-based survey
<p>These are pseudo-anonymised data from the ComBaCaL survey and belong to the manuscript "Prevalence and determinants of cardiovascular risk factors in Lesotho: a population-based survey" which can be found at <a href="https://doi.org/10.1093/inthealth/ihad058">https://doi.org/10.1093/inthealth/ihad058</a>. </p> <p>The data dictionary explains the critical data available in the dataset. Between November 2021 and August 2022 , 6061 participants over 18 years old were visited in their households in two districts of Lesotho. </p>
Risk Factors that modify the familial aggregation for ischemic cardiovascular illness
<p><strong>Introduction:</strong> Ischemic cardiovascular disease is a global health problem. <strong>Objective:</strong> To determine the risk factors that modified the familial aggregation for ischemic cardiovascular disease in affected individuals. <strong>Material and Methods:</strong> An observational, analytical, longitudinal and retrospective case/control study was carried out from the population of the Banes municipality, Holguín province during May 2020-May 2022. The universe included all the diagnosed individuals and their families. By simple random sampling, the sample (149 cases) was obtained and the control group was formed at a ratio of 3:1 (447 individuals with no history of disease). The bioethical requirements were met. Inclusion/exclusion criteria were applied. The statistics were used: Chi square, Odd Ratio (OR), including p and confidence interval. The variables were operationalized: age, degree of consanguinity and risk factors. The family tree was obtained. <strong>Results:</strong> The relatives of first and second degree of consanguinity showed the highest incidence of disease. The age group 60-69 years was more affected. Familial aggregation for the disease was demonstrated (X<sup>2</sup>=45.93 OR=5.85 99.9% CI (3.29; 10.41)). Ischemic cardiomyopathy (43.3%) and arrhythmias (20.7%) were notable forms of presentation. The risk factors showed an association for the disease (X<sup>2</sup>=67.11 p ≤0.001). Arterial hypertension (X<sup>2</sup>=57.9 OR=3.04 99.9% CI (2.27; 4.06)) and smoking (X<sup>2</sup>=45.7 OR=2.66 99.9% CI (2.3 ; 5,6)) expressed a highly significant association for ischemic cardiovascular disease. <strong>Conclusions:</strong> The risk factors: arterial hypertension, smoking and family history modified the family aggregation for ischemic cardiovascular disease.</p>
Risk factors for cardiovascular disease (CVD) in adults with type 1 diabetes: findings from prospective real-life T1D exchange registry
<p>Context</p> <p>Cardiovascular disease (CVD) is a major cause of mortality in adults with type 1 diabetes.</p> <p>Objective</p> <p>We prospectively evaluated CVD risk factors in a large, contemporary cohort of adults with type 1 diabetes living in the United States.</p> <p>Design</p> <p>Observational study of CVD and CVD risk factors over a median of 5.3 years.</p> <p>Setting</p> <p>The T1D Exchange clinic network.</p> <p>Patients</p> <p>Adults (age ≥18 years) with type 1 diabetes and without known CVD diagnosed before or at enrollment.</p> <p>Main Outcome Measure</p> <p>Associations between CVD risk factors and incident CVD were assessed by multivariable logistic regression.</p> <p>Results</p> <p>The study included 8,727 participants (53% female, 88% non-Hispanic white, median age 33 years [IQR=21, 48], type 1 diabetes duration 16 years [IQR=9, 26]). At enrollment, median HbA1c was 7.6% (66 mmol/mol) [IQR=6.9 (52), 8.6 (70)], 33% used a statin, and 37% used blood pressure medication. Over a mean follow-up of 4.6 years, 325 (3.7%) participants developed incident CVD. Ischemic heart disease was the most common CVD event. Increasing age, BMI, HbA1c, presence of hypertension and dyslipidemia, increasing duration of diabetes, and diabetic nephropathy were associated with increased risk for CVD. There were no significant gender differences in CVD risk.</p> <p>Conclusion</p> <p>HbA1c, hypertension, dyslipidemia and diabetic nephropathy are important risk factors for CVD in adults with type 1 diabetes. A longer follow-up is likely required to assess the impact of other traditional CVD risk factors on incident CVD in the current era.</p>
Early Detection Of Cardiovascular Risk Factors And Definition Of Psychosocial Profile In Women Through A Systematic Approach: The Monzino Women Heart Center's Experience
<p>The raw dataset is related to the analysis of CV risk factors and psychosocial profile in women enrolled in a CV prevention program </p>
Associations of serum uric acid with cardiovascular disease risk factors: a retrospective cohort study in Southeastern China
<p class="MsoNormal"><span>Objective: To evaluate the associations between serum uric acid (SUA) levels and cardiovascular disease (CVDs) risk factors, focusing on potential sex-specific differences.</span></p> <p class="MsoNormal"><span>Design: A retrospective cohort study.</span></p> <p class="MsoNormal"><span>Setting: A large community-based survey was conducted every two years from 2010 to 2018 in Hangzhou, Zhejiang Province, Southeastern China.</span></p> <p class="MsoNormal"><span>Participants: 6119 participants aged 40 years and above who underwent at least three times of physical examinations were enrolled. </span></p> <p class="MsoNormal"><span>Methods: Participants were categorized into four groups (Q1-Q4) based on baseline SUA quartiles within the normal range, with hyperuricemia (HUA) as the fifth group. The Q1 was the reference. By stratifying participants by gender, the relationships between SUA levels and systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), and total cholesterol (TC) were investigated using linear regression models in the generalized estimating equation (GEE). Additionally, the associations of elevated SUA levels and HUA with hypertension, hyperglycemia, and dyslipidemia were correspondingly examined using multivariate logistic regression models.</span></p> <p class="MsoNormal"><span>Results: After adjusting for confounding variables, we found positive associations between SUA levels and SBP, DBP, FBG, and TC in women, and with TC in men (P < 0.01). Likewise, Elevated SUA quartiles and HUA were linked to increased dyslipidemia risk in both sexes, and increased hyperglycemia risk only in women, with HRs (95%CI) of 1.64 (1.05-2.55) and 2.37 (1.47-3.81) in the Q4 and HUA group, respectively. Women with HUA had higher hypertension risk (HR=1.45, 95% CI 1.21-1.73), while no such association was observed in men. Stratified analyses revealed significant associations between elevated SUA levels and CVDs risk factors in postmenopausal and non-obese women.</span></p> <p class="MsoNormal"><span>Conclusions: Elevated SUA levels increase the risk of dyslipidemia in both sexes. SUA levels within normal-range and HUA are positively associated with hyperglycemia and hypertension in postmenopausal women, but not in men.</span></p>
Emergent factors of cardiovascular risk epidemiology and global cardiovascular risk
<p><strong>Introduction:</strong> Risk factors determine important clinical implications for cardiovascular prevention. <strong>Objective:</strong> Determine the epidemiology of emerging cardiovascular risk factors and global cardiovascular risk. Method: an observational, analytical, longitudinal and retrospective, case/control investigation was carried out from the individuals evaluated in the cardiology clinic of the Darío Calzadilla Angulo Polyclinic, Banes municipality, Holguín province during May 2021- May 2022. By sampling simple random, the sample was obtained (113 cases). The bioethical requirements were met. Inclusion/exclusion criteria were applied. The following statisticians were used: Chi square, Odd Ratio (OR), including p and confidence interval. The variables were operationalized: sex, age, risk factors, cardiovascular disease, and global cardiovascular risk. The control group was formed at a ratio of 2:1. <strong>Results:</strong> The age groups 60-69 years and 40-49 years prevailed. The female sex predominated. The clinical forms of ischemic cardiomyopathy and arrhythmias had a higher incidence. The associated diseases expressed a significant statistical association for cardiovascular disease, with a predominance of arterial hypertension (OR=2.38), obesity (OR=1.64) and diabetes mellitus (OR=1.79); with increased risk. Emerging cardiovascular risk factors expressed a very significant statistical association for cardiovascular disease with a predominance of high triglyceride quantification values (X2=24.8 OR=3.93 95% CI (2.25;6.86) p=0.000). High global cardiovascular risk was more frequent. <strong>Conclusions:</strong> Emerging cardiovascular risk factors and global cardiovascular risk are mostly modifiable.</p><p><strong>Keyword:</strong> CARDIOVASCULAR DISEASE; EPIDEMIOLOGY; RISK FACTOR'S; GLOBAL CARDIOVASCULAR RISK</p>
Effect of a Unique Web-based Behaviour Change Program on Weight Loss and Cardiovascular Risk Factors
ClinicalTrials.gov study NCT01472276. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study of TAK-875 in Adults With Type 2 Diabetes and Cardiovascular Disease or Risk Factors for Cardiovascular Disease
ClinicalTrials.gov study NCT01609582. IPD Sharing: Not stated. Countries: 32. Publications: 2.
Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in Obese Adolescents
ClinicalTrials.gov study NCT00858247. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of Tocilizumab in Comparison to Etanercept in Participants With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors
ClinicalTrials.gov study NCT01331837. IPD Sharing: Not stated. Countries: 31. Publications: 1.
Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)
ClinicalTrials.gov study NCT01601704. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study of Raisins Versus Alternative Snacks on Cardiovascular Risk Factors In Generally Healthy Subjects
ClinicalTrials.gov study NCT01260272. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Cardiovascular Disease Risk Factors in Chinese American Immigrants
ClinicalTrials.gov study NCT00362128. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Effects of the Dietary Supplement CardioFlex Q10 on Reducing Cardiovascular Disease Risk Factors in Adults
ClinicalTrials.gov study NCT03826914. IPD Sharing: NO. Countries: 1. Publications: 3.
Omega-3 Fatty Acids to Improve Depression and Reduce Cardiovascular Risk Factors
ClinicalTrials.gov study NCT00116857. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Effect Of Capros Supplementation On Cardiovascular Disease Risk Factors In Humans
ClinicalTrials.gov study NCT01858376. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Improving Cardiovascular Risk Factors in Black Young Adults
ClinicalTrials.gov study NCT04412954. IPD Sharing: NO. Countries: 1. Publications: 2.
Reducing Cardiovascular Disease Risk Factors in Rural Communities in North Carolina
ClinicalTrials.gov study NCT02707432. IPD Sharing: NO. Countries: 1. Publications: 2.
Method-of-Use Study Assessing the Effect of Naltrexone Sustained Release (SR)/ Bupropion SR on Body Weight and Cardiovascular Risk Factors in Overweight and Obese Subjects
ClinicalTrials.gov study NCT01764386. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Cardiac Rehabilitation (CR) on Functional Capacity and Cardiovascular Risk Factors
ClinicalTrials.gov study NCT02575976. IPD Sharing: NO. Countries: 1. Publications: 11.
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