Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
128
datasets available to search
ShareScore release 0.9.0
Dataset results
128 results for “cellular differentiation”
Text-fig. 2. Synchrotron radiation X-ray tomographic microscopy volume renderings (a, b) and orthoslices (c–e) of Mugideiriflora portugallica gen. et sp. nov. from the Early Cretaceous Catefica locality, Portugal (holotype, S174254, Catefica sample 150). Yellow dots – stamens, red dots – carpels. a) Flower in lateral view showing the broad bases of the laminar tepals; b) Flower in longitudinal section showing the flat to slightly concave floral receptacle with a central conical gynoecial region (cut between orthoslices yz0800 and 1220); c) Flower in transverse section showing the numerous laminar tepals in several series and the stamens cut in the region of the poorly differentiated anthers; note cellular differences between outer (op) and inner (in) perianth parts, as well as and transverse sections of anthers, apparently with laterally to slightly dorsally placed pollen sacs (arrow heads) (cut at orthoslice xy0770); d) Flower in transverse section showing the numerous laminar tepals in several series, flattened rhomboidal stamen bases in several series, and poorly differentiated carpels (cut at orthoslice xy0820); e) Flower in transverse section showing the numerous laminar tepals in several series, flattened rhomboidal stamen bases in several series, and poorly differentiated carpels (cut at orthoslice xy0920); f) Flower in longitudinal section showing the shallowly concave floral receptacle with laminar tepals, stamens, and a central conical gynoecial region bearing poorly differentiated carpels (cut at orthoslice yz0900); g) Flower in longitudinal section perpendicular to that in (f) showing stamens and poorly differentiated carpels (cut at orthoslice xz1630). Scale bars = 1 mm (a, b), 500 µm (c–g). in Multiparted, Apocarpous Flowers From The Early Cretaceous Of Eastern North America And Portugal
Text-fig. 2. Synchrotron radiation X-ray tomographic microscopy volume renderings (a, b) and orthoslices (c–e) of Mugideiriflora portugallica gen. et sp. nov. from the Early Cretaceous Catefica locality, Portugal (holotype, S174254, Catefica sample 150). Yellow dots – stamens, red dots – carpels. a) Flower in lateral view showing the broad bases of the laminar tepals; b) Flower in longitudinal section showing the flat to slightly concave floral receptacle with a central conical gynoecial region (cut between orthoslices yz0800 and 1220); c) Flower in transverse section showing the numerous laminar tepals in several series and the stamens cut in the region of the poorly differentiated anthers; note cellular differences between outer (op) and inner (in) perianth parts, as well as and transverse sections of anthers, apparently with laterally to slightly dorsally placed pollen sacs (arrow heads) (cut at orthoslice xy0770); d) Flower in transverse section showing the numerous laminar tepals in several series, flattened rhomboidal stamen bases in several series, and poorly differentiated carpels (cut at orthoslice xy0820); e) Flower in transverse section showing the numerous laminar tepals in several series, flattened rhomboidal stamen bases in several series, and poorly differentiated carpels (cut at orthoslice xy0920); f) Flower in longitudinal section showing the shallowly concave floral receptacle with laminar tepals, stamens, and a central conical gynoecial region bearing poorly differentiated carpels (cut at orthoslice yz0900); g) Flower in longitudinal section perpendicular to that in (f) showing stamens and poorly differentiated carpels (cut at orthoslice xz1630). Scale bars = 1 mm (a, b), 500 µm (c–g).
Text-fig. 1. Scanning electron micrographs of Mugideiriflora portugallica gen. et sp. nov. from the Early Cretaceous Catefica locality, Portugal (holotype, S174254, Catefica sample 150). a) Flower in oblique lateral view showing numerous broad tepals, numerous inwardly curved stamens and the flat floral receptacle with a conical gynoecial region; b–c) Flower in two different oblique apical views showing numerous broad laminar tepals and inwardly curved stamens surrounding the carpels; note cellular differences between outer (op) and inner (in) perianth parts, as well as bases of anthers, apparently with laterally to slightly dorsally placed pollen sacs (arrow heads); d) Detail of flower showing a cluster of poorly differentiated carpels in the center surrounded by elongated stamens; note grooves in the dorsal surface of the stamens indicating the position of the pollen sacs; e) Detail of flower showing the broad bases of the laminar tepals, rhomboidal stamen bases and poorly differentiated carpels; f) Detail of flower showing inwardly arched stamens and poorly differentiated carpels. Scale bars = 1 mm (a–c), 200 µm (d–f). in Multiparted, Apocarpous Flowers From The Early Cretaceous Of Eastern North America And Portugal
Text-fig. 1. Scanning electron micrographs of Mugideiriflora portugallica gen. et sp. nov. from the Early Cretaceous Catefica locality, Portugal (holotype, S174254, Catefica sample 150). a) Flower in oblique lateral view showing numerous broad tepals, numerous inwardly curved stamens and the flat floral receptacle with a conical gynoecial region; b–c) Flower in two different oblique apical views showing numerous broad laminar tepals and inwardly curved stamens surrounding the carpels; note cellular differences between outer (op) and inner (in) perianth parts, as well as bases of anthers, apparently with laterally to slightly dorsally placed pollen sacs (arrow heads); d) Detail of flower showing a cluster of poorly differentiated carpels in the center surrounded by elongated stamens; note grooves in the dorsal surface of the stamens indicating the position of the pollen sacs; e) Detail of flower showing the broad bases of the laminar tepals, rhomboidal stamen bases and poorly differentiated carpels; f) Detail of flower showing inwardly arched stamens and poorly differentiated carpels. Scale bars = 1 mm (a–c), 200 µm (d–f).
Data from: Plasticity and the evolution of group-level regulation of cellular differentiation in the volvocine algae
Open the record for dataset details and reuse information.
Plant species with higher chemical defenses enhance herbivore cellular immunity with differential effectiveness against two parasitoid species
<p>Insect herbivores simultaneously experience bottom-up effects of plant defensive chemistry and the top-down effects of natural enemies. At the intersection of these effects are herbivore immune systems, herbivore traits that have largely been overlooked in studies of plant-insect interactions. Most previous studies have demonstrated compromised immunity of herbivores that feed on plants with higher defensive chemistry. Many studies have used embedded microfilaments or silica beads as proxies for parasitoid eggs. Yet, parasitoids may evade or suppress host immune responses by injecting venom, calyx fluid, or through modifications of their egg surface structure, necessitating studies that include all three trophic levels to obtain a complete picture of how plant traits may modulate herbivore immunity.Here we examined the effect of host plant species that differ in glucosinolate (anti-herbivore compounds produced by plants in the Brassicaceae) concentrations on the immune status of an herbivore and its consequences for two species of parasitoids with different life history traits.We found that larvae of the butterfly Pieris rapae that fed on field mustard Brassica rapa, which contain 52-fold higher glucosinolate concentrations than collards B. oleracea, attained lower body weights and experienced prolonged development to adulthood.Yet, caterpillars that fed on B. rapa had enhanced cellular immunity, as measured by total and differential hemocyte counts, as well as melanization capacity compared to larvae that fed on B. oleracea.In turn, the likelihood that at least some eggs in clutches of the gregarious endoparasitoid Cotesia glomerata would be encapsulated, leading to a reduction in brood size, were three times greater when their host caterpillars fed on B. rapa compared to B. oleracea. Interestingly, eggs of the solitary endoparasitoid Cotesia rubecula were rarely encapsulated irrespective of the host plant on which their host caterpillar fed. Therefore, our results suggest that plant defense metabolites can influence the expression of herbivore immunity, but the effectiveness of this response strongly depends on the identity of the parasitoid and its ability to evade the caterpillar immune response, and possibly the evolution of these trophic interactions in non-native systems.</p>
Plant species with higher chemical defenses enhance herbivore cellular immunity with differential effectiveness against two parasitoid species
Open the record for dataset details and reuse information.
Phylotranscriptomics points to multiple independent origins of multicellularity and cellular differentiation in the volvocine algae
<p class="western">The volvocine algae, which include the single-celled species <i>Chlamydomonas reinhardtii</i> and the colonial species <i>Volvox carteri</i>, serve as a model in which to study the evolution of multicellularity and cellular differentiation. Studies reconstructing the history of this group have by and large relied on datasets of one to a few genes for phylogenetic inference and ancestral character state reconstruction. As a result, volvocine phylogenies lack concordance depending on the number and/or type of genes (i.e., chloroplast vs nuclear) chosen for phylogenetic inference. While multiple studies suggest that multicellularity evolved only once in the volvocine algae, that each of its three colonial families is monophyletic, and that there have been at least three independent origins of cellular differentiation in the group, other studies call into question one or more of these conclusions. An accurate assessment of the evolutionary history of the volvocine algae requires inference of a more robust phylogeny. We performed RNA sequencing (RNA-seq) on 55 strains representing 47 volvocine algal species and obtained similar data from curated databases on 13 additional strains. We then compiled a dataset consisting of transcripts for 40 single-copy, protein-coding, nuclear genes, and subjected the predicted amino acid sequences of these genes to maximum likelihood, Bayesian inference, and coalescent-based analyses. These analyses show that multicellularity independently evolved at least twice in the volvocine algae and that the colonial family Goniaceae is not monophyletic. Our data further indicate that cellular differentiation arose independently at least four, and possibly as many as six times, within the volvocine algae. Altogether, our results demonstrate that multicellularity and cellular differentiation are evolutionarily labile in the volvocine algae, affirming the importance of this group as a model system for the study of major transitions in the history of life.</p>
Fluctuation of cellular differentiation in limb regeneration is regulated by Pde4b in urodele amphibians
Open the record for dataset details and reuse information.
Phylotranscriptomics points to multiple independent origins of multicellularity and cellular differentiation in the volvocine algae
Open the record for dataset details and reuse information.
Data from: Differential chromosome conformations as hallmarks of cellular identity revealed by mathematical polymer modeling
Inherently dynamic, chromosomes adopt many different conformations in response to DNA metabolism. Models of chromosome organization in the yeast nucleus obtained from genome-wide chromosome conformation data or biophysical simulations provide important insights into the average behavior but fail to reveal features from dynamic or transient events that are only visible in a fraction of cells at any given moment. We developed a method to determine chromosome conformation from relative positions of three fluorescently tagged DNA in living cells imaged in 3D. Cell type specific chromosome folding properties could be assigned based on positional combinations between three loci on yeast chromosome 3. We determined that the shorter left arm of chromosome 3 is extended in MATα cells, but can be crumpled in MATa cells. Furthermore, we implemented a new mathematical model that provides for the first time an estimate of the relative physical constraint of three linked loci related to cellular identity. Variations in this estimate allowed us to predict functional consequences from chromatin structural alterations in asf1 and recombination enhancer deletion mutant cells. The computational method is applicable to identify and characterize dynamic chromosome conformations in any cell type.
Expression proteomics and histone analysis reveals extensive chromatin network changes and a role for histone tail trimming during cellular differentiation
Open the record for dataset details and reuse information.
Data from: Differential chromosome conformations as hallmarks of cellular identity revealed by mathematical polymer modeling
Open the record for dataset details and reuse information.
Classical Hodgkin lymphoma shows epigenetic features of an abortive plasma cellular differentiation: acetyl H3 K9/14 ChIP-chip
GEO Series GSE21253. Homo sapiens. 9 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
GEO Series GSE149457. Gallus gallus. 11 samples. Type: Expression profiling by high throughput sequencing.
CTCF depletion uncouples the role of enhancer-promoter interactions and higher-order chromatin hubs in gene regulation during cellular differentiation.
GEO Series GSE263641. Homo sapiens. 137 samples. Type: Other; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Transcriptional Program of Kpna2 (Importin-α2) Regulates Cellular Differentiation-Coupled Circadian Clock Development in Mammalian Cells
GEO Series GSE61096. Mus musculus. 4 samples. Type: Expression profiling by array.
Acyl-CoA synthetase 1 in differentiated adipocytes from small for gestational age neonates: Putative association with fetal programming of cellular insulin sensitivity and lipid content [Set1B: adipog
GEO Series GSE64699. Homo sapiens. 28 samples. Type: Expression profiling by array.
Apc restoration promotes cellular differentiation and reestablishes crypt homeostasis in colorectal cancer
GEO Series GSE67186. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Culture conditions differentially regulate the inflammatory niche and cellular phenotype of tracheobronchial basal stem cells
GEO Series GSE224243. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Integrated detection of both 5-mC and 5-hmC by high-throughput tag sequencing technology highlights methylation reprogramming of bivalent genes during cellular differentiation [DGE]
GEO Series GSE40953. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Mitochondrial Calcium Exchange links Metabolism with the Epigenome to Control Cellular Differentiation (RNA-seq)
GEO Series GSE135529. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.