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146 results for “cisplatin resistance”

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zenodo40/100

Valproic Acid Synergizes With Cisplatin and Cetuximab in vitro and in vivo in Head and Neck Cancer by Targeting the Mechanisms of Resistance - Unpublished data

<p>Antitumor effects of valproic acid (VPA) in combination with Cisplatin/Cetuximab doublet in head and neck squamous cell carcinoma (HNSCC) models. We reported unpublished data of the effects of this combination on cell cycle and 3D cell cultures</p>

opencc-by-4.0Aug 2021View details →
zenodo36/100

Acidic Microenvironment Enhances Cisplatin Resistance in Bladder Cancer via Bcl-2 and XIAP

Open the record for dataset details and reuse information.

opencc-by-4.0Sep 2024View details →
ClinicalTrials.gov32/100

3-AP and Cisplatin in Treating Patients With Recurrent or Persistent Platinum-Resistant Ovarian Epithelial or Primary Peritoneal Cancer

ClinicalTrials.gov study NCT00081276. IPD Sharing: Not stated. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
zenodo28/100

Figure 4 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 4 The anti-proliferative assay (MTT) was used to examine the EMT-6/P and EMT-6/CPR cell lines' sensitivity to cisplatin at varying doses.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 16 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 16 Effect of TQ (25 mg/kg), silymarin (50 mg/kg), their combinations, cisplatin (0.7 mg/kg), and control group on serum ALT level measured by (IU/L).

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 10 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 10 Folds increase in caspase-3 activity and apoptosis induction in concentrations of TQ (10 µM), silymarin (10 µM), and their combination in EMT-6/CPR cell line.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 15 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 15 Changes of tumor sizes in EMT-6/CPR after dissection at day 10 in all groups compared to each other, n = 7.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 14 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 14 A plot of change in average tumor size (mm³) vs. time in (days) of treatment in EMT-6/CPR cell line.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 21 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 21 Showed that there is no significant difference in serum creatinine between the healthy group and other treatment groups except cisplatin group. This graph was obtained by GraphPad Prism.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 9 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 9 Demonstrates concentration of Caspase-3 in ng/ml in each treatment group along with the control group.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 7 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 7 Anti-proliferation activity of several concentrations of TQ with 106.63 µM silymarin against EMT-6/CPR cell lines.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 13 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 13 Shows that the percentage of change in tumor volume in EMT-6/CPR cell line was significant (P-value &lt; 0.05) in all treatment groups except the silymarin group. This graph was obtained using GraphPad prism.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 18 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 18 Effect of TQ (25 mg/kg), silymarin (50 mg/kg), their combinations, cisplatin (0.7 mg/kg), and control group on serum AST level measured by (IU/L).

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 12 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 12 A plot of change in average tumor size (mm³) vs. time in (days) of treatment in EMT-6/P cell line.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 6 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 6 Anti-proliferation activity of various concentrations of silymarin with 29.58 µM TQ against EMT-6/P cell lines.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 5 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 5 Anti-proliferation activity of various concentrations of TQ with 142.40 µM silymarin against EMT-6/P cell lines.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 17 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 17 Showed that there is no significant (ns) difference in serum ALT between the healthy group and other treatment groups. This graph was obtained by GraphPad Prism.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 2 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 2 Anti-proliferation effect of TQ in single treatment against EMT-6/P and EMT-6/CPR cell lines.

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 20 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 20 Effect of TQ (25 mg/kg), silymarin (50 mg/kg), their combinations, cisplatin (0.7 mg/kg), and control group on serum creatinine level measured by (mg/dl).

opencc-by-4.0Mar 2024View details →
zenodo28/100

Figure 19 from: Hamed RA, Talib WH (2024) Targeting cisplatin resistance in breast cancer using a combination of Thymoquinone and Silymarin: an in vitro and in vivo study. Pharmacia 71: 1-19. https://doi.org/10.3897/pharmacia.71.e117997

Figure 19 Showed that there is no significant difference in serum AST between the healthy group and other treatment groups. This graph was obtained by GraphPad Prism.

opencc-by-4.0Mar 2024View details →

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International Brain Laboratory public data

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