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37 results for “cold shock”
Fig. 1 in Oxidative stress parameters in juvenile Brazilian flounder Paralichthys orbignyanus (Valenciennes, 1839) (Pleuronectiformes: Paralichthyidae) exposed to cold and heat shocks
Fig. 1. (TBARS), (GST) and (CAT) activity in the liver of Paralichthys orbignyanus juveniles exposed to different temperatures (17.1, 23.0 and 28.8ºC) as a function of time exposition (72 h). Values are expressed as means ± SEM, N=5. aLower case letters indicate significantly different at the different temperatures and same time (P <0.05), determined by two-way ANOVA and by Dunnet test. ACapital letters indicate significantly different at the same temperatures and different times (P <0.05), determined by two-way ANOVA and by Dunnet test.
Cold Stored Platelet in Hemorrhagic Shock
ClinicalTrials.gov study NCT04667468. IPD Sharing: YES. Countries: 1. Publications: 1.
Raw Western blots data to assess cold shock protein expression
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Data from: Metabolomic and transcriptomic responses of ticks during recovery from cold shock reveal mechanisms of survival
<p>Ticks are blood-feeding ectoparasites but spend most of their life off-host where they may have to tolerate low winter temperatures. Rapid cold-hardening (RCH) is a process commonly used by arthropods, including ticks, to improve survival of acute low temperature exposure. However, little is known about the underlying mechanisms in ticks associated with RCH, cold shock, and recovery from these stresses. In the present study, we investigated the extent to which RCH influences gene expression and metabolism during recovery from cold stress in Dermacentor variabilis, the American dog tick, using a combined transcriptomics and metabolomics approach. Following recovery from RCH, 1,860 genes were differentially expressed in ticks, whereas only 99 genes responded during recovery to direct cold shock. Recovery from RCH resulted in an upregulation of various pathways associated with ion binding, transport, metabolism, and cellular structures seen in the response of other arthropods to cold. The accumulation of various metabolites, including several amino acids and betaine, corresponded to transcriptional shifts in the pathways associated with these molecules, suggesting congruent metabolome and transcriptome changes. Ticks receiving exogenous betaine and valine demonstrated enhanced cold tolerance, suggesting cryoprotective effects of these metabolites. Overall, many of the responses during recovery from cold shock in ticks were similar to those observed in other arthropods, but several adjustments may be distinct from other currently examined taxa.</p>
Alteration of DNA supercoiling serves as a trigger of short-term cold shock repressed genes of E. coli
<p><span>Cold shock adaptability is a key survival skill of gut </span><span>bacteria of warm-blooded animals. <em>Escherichia coli</em> cold shock responses are controlled by a complex multi-gene, timely-ordered transcriptional program. We investigated its underlying mechanisms. Having identified short-term, cold shock repressed genes, we show that their responsiveness is unrelated to their transcription factors or global regulators, while</span><span> their single-cell protein numbers' variability increases after cold shock. We hypothesized that some </span><span>cold shock repressed </span><span>genes could be triggered by high propensity for transcription locking due to changes in DNA supercoiling (likely due to DNA relaxation caused by an overall reduction in negative supercoiling). </span><span>Concomitantly, we found that nearly half of cold shock repressed genes are also highly responsive to gyrase inhibition (albeit most genes responsive to gyrase inhibition are not cold shock responsive). Further, their response strengths to cold shock and gyrase inhibition correlate. Meanwhile, under cold shock, nucleoid density increases, and gyrases and nucleoid become more colocalized. Moreover, the cellular energy decreases, which may hinder positive supercoils resolution. Overall, we conclude that sensitivity to diminished negative supercoiling is a core feature of <em>E. coli</em>'s short-term, cold shock transcriptional program, and could be used to regulate the temperature sensitivity of synthetic circuits.</span></p>
ROS and SGI data for manuscript "The perception and evolution of flagellin, cold shock protein, and elongation factor Tu from vector-borne bacterial plant pathogens"
<p>This contains raw data for the ROS and seedling growth inhibition (SGI) assays collected for the manuscript "The perception and evolution of flagellin, cold shock protein, and elongation factor Tu from vector-borne bacterial plant pathogens". For a quick reference, there are two spreadsheets listing all the Max RLUs and Z-scores for the experiments, but the actual output of each plate reader is also included. </p>
Data from: Metabolomic and transcriptomic responses of ticks during recovery from cold shock reveal mechanisms of survival
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Alteration of DNA supercoiling serves as a trigger of short-term cold shock repressed genes of E. coli
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Data from: Egg viability, mating frequency and male mating ability evolve in populations of Drosophila melanogaster selected for resistance to cold shock
Background: Ability to resist temperature shock is an important component of fitness of insects and other ectotherms. Increased resistance to temperature shock is known to affect life-history traits. Temperature shock is also known to affect reproductive traits such as mating ability and viability of gametes. Therefore selection for increased temperature shock resistance can affect the evolution of reproductive traits. Methods: We selected replicate populations of Drosophila melanogaster for resistance to cold shock. We then investigated the evolution of reproductive behavior along with other components of fitness- larval survivorship, adult mortality, fecundity, egg viability in these populations. Results: We found that larval survivorship, adult mortality and fecundity post cold shock were not significantly different between selected and control populations. However, compared to the control populations, the selected populations laid significantly higher percentage of fertile eggs (egg viability) 24 hours post cold shock. The selected populations had higher mating frequency both with and without cold shock. After being subjected to cold shock, males from the selected populations successfully mated with significantly more non-virgin females and sired significantly more progeny compared to control males. Conclusions: A number of studies have reported the evolution of survivorship in response to selection for temperature shock resistance. Our results clearly indicate that adaptation to cold shock can involve changes in components of reproductive fitness. Our results have important implications for our understanding of how reproductive behavior can evolve in response to thermal stress.
Fig. 2 in Oxidative stress parameters in juvenile Brazilian flounder Paralichthys orbignyanus (Valenciennes, 1839) (Pleuronectiformes: Paralichthyidae) exposed to cold and heat shocks
Fig. 2. (TBARS), (GST) and (CAT) activity in the gills of Paralichthys orbignyanus juveniles exposed to different temperatures (17.1, 23.0 and 28.8ºC) as a function of time exposition (72 h). Values are expressed as means ± SEM, N=5. aLower case letters indicate significantly different at the different temperatures and same time (P <0.05), determined by two-way ANOVA and by Dunnet test. ACapital letters indicate significantly different at the same temperatures and different times (P <0.05), determined by two-way ANOVA and by Dunnet test.
Data from: Egg viability, mating frequency and male mating ability evolve in populations of Drosophila melanogaster selected for resistance to cold shock
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RNA-seq-based analysis of the physiologic cold shock-induced changes in Moraxella catarrhalis gene expression
GEO Series GSE46256. Moraxella catarrhalis O35E. 6 samples. Type: Expression profiling by high throughput sequencing.
A stress response that monitors and regulates mRNA structure is central to cold-shock adaptation
GEO Series GSE103421. Escherichia coli; Escherichia coli str. K-12 substr. MG1655. 55 samples. Type: Expression profiling by high throughput sequencing; Other.
Response of Rhodopirellula baltica to cold shock
GEO Series GSE13856. Rhodopirellula baltica SH 1; Rhodopirellula baltica. 18 samples. Type: Expression profiling by array.
Glomerular-tubular crosstalk via cold shock Y-box binding protein-1 in the kidney
GEO Series GSE239313. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Complete genome sequence of Vibrio parahaemolyticus CHN25 and transcriptomic analysis of cold shock proteins of VpaCspA and VpaCspD in the adaptation of low temperature growth
GEO Series GSE65998. Vibrio parahaemolyticus. 4 samples. Type: Expression profiling by high throughput sequencing.
Identification of genes involved in cold shock response in rainbow trout (Oncorhynchus mykiss)
GEO Series GSE75563. Oncorhynchus mykiss; Salmo salar. 24 samples. Type: Expression profiling by array.
Whole-genome CRISPR screen to identify regulators of cold-shock protein RBM3
GEO Series GSE217789. Homo sapiens. 12 samples. Type: Other.
Transcriptomic analysis of (Group I) Clostridium botulinum ATCC 3502 cold shock response
GEO Series GSE51465. Clostridium botulinum; Clostridium botulinum A str. ATCC 3502. 6 samples. Type: Expression profiling by array.
Cellular RNA Targets of Cold Shock Proteins CspC and CspE and Their Importance for Serum Resistance in Septicemic Escherichia coli
GEO Series GSE205384. Escherichia coli. 12 samples. Type: Other.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.