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37 results for “deactivation”
Dataset of "Impact of Carbon Corrosion and Denitrogenation on the Deactivation of Fe-N-C Catalysts in Alkaline Media"
<p>In this work, we use a gas diffusion electrode half-cell coupled with inductively coupled plasma mass spectrometry (GDE-ICP-MS) to quantify the Fe dissolution rates in the potential range between 0.93 and 1.5 VRHE. It is shown that Fe dissolution accelerates with increased anodic potential and temperature while it is independent on the presence/absence of O2. The onset potential of Fe dissolution at room temperature agrees with the reported onset potentials of carbon corrosion and denitrogenation, C and N being oxidized to gaseous COx and NOx species, respectively. This correlation supports that the electrochemical oxidation of the N-C matrix triggers the observed catalyst demetallation in these conditions. Using a set of ex situ physicochemical characterization techniques, including spectroscopy and microscopy, the various degrees of degradation under three sets of experimental conditions of interest (O2-RT, O2-HT, and Ar-HT, where RT = 22℃ and HT = 62℃) are rationalized. Combining the GDE-ICP-MS technique and post-mortem analyses, this work provides novel insights into the degradation pathways of various Fe, N, and C species during start-stop events, which may inspire the next generation of durable Fe-N-C catalysts for anion exchange membrane fuel cells.</p>
Molecular Dynamics simulations suggest possible activation and deactivation pathways in hERG channel
<ol> <li>equil_gating_4_assembly_xleap.prmtop: file topology of the hERG closed state with gating charge 4 equilibration trajectory</li> <li>equil_gating_6_assembly_xleap.prmtop: file topology of the hERG closed state with gating charge 6 equilibration trajectory</li> <li>equil_gating_8_assembly_xleap.prmtop: file topology of the hERG closed state with gating charge 8 equilibration trajectory</li> <li>equil_gating_4.dcd: 100 ns NPT trajectory of the hERG closed state with gating charge 4</li> <li>equil_gating_6.dcd: 100 ns NPT trajectory of the hERG closed state with gating charge 6</li> <li>equil_gating_8.dcd: 100 ns NPT trajectory of the hERG closed state with gating charge 8</li> <li>equil_open_assembly_xleap.prmtop: file topology of the hERG open state equilibration trajectory</li> <li>equil_open.dcd: 100 ns NPT trajectory of the hERG open state</li> <li>herg_closed_gating_4.pdb: PDB file of hERG closed state with gating charge 4 after Steered MD simulations</li> <li>herg_closed_gating_6.pdb: PDB file of hERG closed state with gating charge 6 after Steered MD simulations</li> <li>herg_closed_gating_8.pdb: PDB file of hERG closed state with gating charge 8 after Steered MD simulations</li> <li>TMD_O-C_closed_gating_8_assembly_xleap.prmtop: file topology of the hERG closed state with gating charge 8 TMD trajectory</li> <li>TMD_O-C_closed_gating_6_assembly_xleap.prmtop: file topology of the hERG closed state with gating charge 6 TMD trajectory</li> <li>TMD_O-C_closed_gating_4_assembly_xleap.prmtop: file topology of the hERG closed state with gating charge 4 TMD trajectory</li> <li>TMD_O-C_closed_gating_8.dcd: TMD trajectory of the hERG closed state with gating charge 8</li> <li>TMD_O-C_closed_gating_6.dcd: TMD trajectory of the hERG closed state with gating charge 6</li> <li>TMD_O-C_closed_gating_4.dcd: TMD trajectory of the hERG closed state with gating charge 4</li> </ol> <p>MD trajectories (equilibration and Targeted MD trajectories) in dcd format can be visualized using visualization tools such as VMD or PyMol after uploading the topology file.</p> <p>The directory data_supplementary-note-4.tar.bz2 contains the files related to the Supplementary Notes 4: "A practical example of pathway calculation".</p>
A novel autism-associated KCNB1 mutation dramatically slows Kv2.1 potassium channel gating activation, deactivation and inactivation
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Intratissue Electrolysis (EPI) is Effective in Deactivating Myofascial Trigger Points (MTrPs). (EPIEMG)
ClinicalTrials.gov study NCT07351331. IPD Sharing: NO. Countries: 1. Publications: 6.
Deactivation of Implantable Cardioverter Defibrillator During Non-thoracic Surgical Procedures
ClinicalTrials.gov study NCT00806377. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Comparison of Scar Infiltration, Scar Deactivation, and Standard of Care for the Treatment of Chronic, Post-Surgical Pain After Cesarean Section
ClinicalTrials.gov study NCT03936309. IPD Sharing: NO. Countries: 1. Publications: 12.
An Intervention to Improve Implantable Cardioverter-Defibrillator Deactivation Conversations
ClinicalTrials.gov study NCT01459744. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury
ClinicalTrials.gov study NCT05758077. IPD Sharing: NO. Countries: 1. Publications: 31.
Dataset: Cross-coupling of Mo- and V-Nitrogenases Permits Protein-Mediated Protection from Oxygen Deactivation
<p>Dataset for <strong>DOI: 10.1002/cbic.202400585</strong></p> <p><strong>https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202400585</strong></p> <p> </p>
Data from: Deactivation in the posterior mid-cingulate cortex reflects perceptual transitions during binocular rivalry: evidence from simultaneous EEG-fMRI
Binocular rivalry is a phenomenon in which perception spontaneously shifts between two different images that are dichoptically presented to the viewer. By elucidating the cortical networks responsible for these stochastic fluctuations in perception, we can potentially learn much about the neural correlates of visual awareness. We obtained concurrent EEG-fMRI data for a group of 20 healthy human subjects during the continuous presentation of dichoptic visual stimuli. The two eyes' images were tagged with different temporal frequencies so that eye specific steady-state visual evoked potential (SSVEP) signals could be extracted from the EEG data for direct comparison with changes in fMRI BOLD activity associated with binocular rivalry. We additionally included a smooth replay condition that emulated the perceptual transitions experienced during binocular rivalry as a control stimulus. We evaluated a novel SSVEP-informed fMRI analysis in this study in order to delineate the temporal dynamics of rivalry-related BOLD activity from both an electrophysiological and behavioral perspective. In this manner, we assessed BOLD activity during rivalry that was directly correlated with peaks and crosses of the two rivaling, frequency-tagged SSVEP signals, for comparison with BOLD activity associated with subject reported perceptual transitions. Our findings point to a critical role of a right lateralized fronto-parietal network in the processing of bistable stimuli, given that BOLD activity in the right superior/inferior parietal lobules was significantly elevated throughout binocular rivalry and in particular during perceptual transitions, compared with the replay condition. Based on the SSVEP-informed analysis, rivalry was further associated with significantly enhanced BOLD suppression in the posterior mid-cingulate cortex during perceptual transitions, compared with SSVEP crosses. Overall, this work points to a careful interplay between early visual areas, the right posterior parietal cortex and the mid-cingulate cortex in mediating the spontaneous perceptual changes associated with binocular rivalry and has significant implications for future multimodal imaging studies of perception and awareness.
Data from: Deactivation in the posterior mid-cingulate cortex reflects perceptual transitions during binocular rivalry: evidence from simultaneous EEG-fMRI
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MODD mediates deactivation and degradation of OsbZIP46 to negatively regulate ABA signaling and drought resistance in rice
GEO Series GSE83075. Oryza sativa Japonica Group. 4 samples. Type: Expression profiling by high throughput sequencing.
A novel deactivation factor of fibrogenic hepatic stellate cells induces regression of liver fibrosis in mice
GEO Series GSE128895. Mus musculus. 8 samples. Type: Expression profiling by array.
The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer [RNA-Seq]
GEO Series GSE66232. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Polycomb-mediated deactivation of AR-feedback loop leads to castration-resistant prostate cancer [gene expression]
GEO Series GSE79356. Homo sapiens. 10 samples. Type: Expression profiling by array.
Polycomb-mediated deactivation of AR-feedback loop leads to castration-resistant prostate cancer [ChIP-seq]
GEO Series GSE79357. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The small molecule Pifithrin–α deactivates ETR1 to repress shade avoidance in Arabidopsis
GEO Series GSE272795. Arabidopsis thaliana. 13 samples. Type: Expression profiling by high throughput sequencing.
Impeding transcription of expanded microsatellite repeats by deactivated Cas9
GEO Series GSE103997. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation
GEO Series GSE133529. Sus scrofa. 16 samples. Type: Expression profiling by high throughput sequencing.
Histone H3K4 methylation regulates deactivation of the Spindle Assembly Checkpoint through direct binding of Mad2
GEO Series GSE80575. Saccharomyces cerevisiae. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.