Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
20
datasets available to search
ShareScore release 0.7.1
Dataset results
20 results for “deer mice”
Data for: Adaptive tail-length evolution in deer mice is associated with differential Hoxd13 expression in early development
<p>Variation in the size and number of axial segments underlies much of the diversity in animal body plans. Here, we investigate the evolutionary, genetic, and developmental mechanisms driving tail-length differences between forest and prairie ecotypes of deer mice (<em>Peromyscus maniculatus</em>). We first show that long-tailed forest mice perform better in an arboreal locomotion assay, consistent with tails being important for balance during climbing. We then identify six genomic regions that contribute to differences in tail length, three of which associate with caudal vertebra length and the other three with vertebra number. For all six loci, the forest allele increases tail length, indicative of the cumulative effect of natural selection. Two of the genomic regions associated with variation in vertebra number contain Hox gene clusters. Of those, we find an allele-specific decrease in Hoxd13 expression in the embryonic tail bud of long-tailed forest mice, consistent with its role in axial elongation. Additionally, we find that forest embryos have more presomitic mesoderm than prairie embryos, and that this correlates with an increase in the number of neuromesodermal progenitors (NMPs), which are modulated by Hox13 paralogs. Together, these results suggest a role for Hoxd13 in the development of natural variation in adaptive morphology on a microevolutionary timescale.</p>
Incomplete genetic compensation and countergradient variation of blood-oxygen transport in deer mice
Open the record for dataset details and reuse information.
Dominant deer mice show the importance of abundance in competition
Open the record for dataset details and reuse information.
Data for: Adaptive tail-length evolution in deer mice is associated with differential Hoxd13 expression in early development
Open the record for dataset details and reuse information.
Coordinated changes across the O2 transport pathway underlie adaptive increases in thermogenic capacity in high-altitude deer mice
Open the record for dataset details and reuse information.
Data from: Botfly infections impair the aerobic performance and survival of montane populations of deer mice, Peromyscus maniculatus rufinus
1. Elevations >2000 m represent consistently harsh environments for small endotherms because of abiotic stressors such as cold temperatures and hypoxia. 2. These environmental stressors may limit the ability of populations living at these elevations to respond to biotic selection pressures — such as parasites or pathogens — that in other environmental contexts would impose only minimal energetic- and fitness-related costs. 3. We studied deer mice (Peromyscus maniculatus rufinus) living along two elevational transects (2300 – 4400 m) in the Colorado Rockies and found that infection prevalence by botfly larvae (Cuterebridae) declined at higher elevations. We found no evidence of infections at elevations > 2400 m, but that 33.6% of all deer mice, and 52.2% of adults, were infected at elevations < 2400 m. 4. Botfly infections were associated with reductions in hematocrit levels of 23%, hemoglobin concentrations of 27%, and cold-induced VO2max measures of 19% compared to uninfected individuals. In turn, these reductions in aerobic performance appeared to influence fitness, as infected individuals suffered 19-34% higher overwinter mortality. 5. In contrast to studies at lower elevations, we found evidence indicating that botfly infections influence the aerobic capabilities and fitness of deer mice living at elevations between 2000 – 2400 m. Our results therefore suggest that the interaction between botflies and small rodents is likely highly context-dependent and that, more generally, high-elevation populations may be susceptible to additional biotic selection pressures.
Data from: Microsatellite genetic structure and cytonuclear discordance in naturally fragmented populations of deer mice (Peromyscus maniculatus)
The Great Lakes impose high levels of natural fragmentation on local populations of terrestrial animals in a way rarely found within continental ecosystems. Although separated by major water barriers, woodland deer mouse (Peromyscus maniculatus gracilis) populations on the islands and on the Upper Peninsula (UP) and Lower Peninsula (LP) of Michigan have previously been shown to have a mitochondrial DNA contact zone that is incongruent with the regional landscape. We analyzed 11 microsatellite loci for 16 populations of P. m. gracilis distributed across 2 peninsulas and 6 islands in northern Michigan to address the relative importance of geographical structure and inferred postglacial colonization patterns in determining the nuclear genetic structure of this species. Results showed relatively high levels of genetic structure for this species and a significant correlation between interpopulation differentiation and separation by water but little genetic structure and no isolation-by-distance within each of the 2 peninsulas. Genetic diversity was generally high on both peninsulas but lower and correlated to island size in the Beaver Island Archipelago. These results are consistent with the genetic and demographic isolation of Lower Peninsula populations, which is a matter of concern given the dramatic decline in P. m. gracilis abundance on the Lower Peninsula in recent years.
Linking genetic, morphological, and behavioural divergence between inland island and mainland deer mice
<p>The island syndrome hypothesis (ISH) stipulates that, as a result of local selection pressures and restricted gene flow, individuals from island populations should differ from individuals within mainland populations. Specifically, island populations are predicted to contain individuals that are larger, less aggressive, more sociable, and that invest more in their offspring. To date, tests of the ISH have mainly compared oceanic islands to continental sites, and rarely smaller spatial scales such as inland watersheds. Here, using a novel set of genome-wide SNP markers in wild deer mice (Peromyscus maniculatus) we conducted a genomic assessment of predictions underlying the ISH in an inland riverine island system: analysing island-mainland population structure, and quantifying heritability of phenotypes thought to underlie the ISH. We found clear genomic differentiation between island and mainland populations and moderate to high marker-based heritability estimates fo r overall variation in traits previously found to differ in line with the ISH between mainland and island locations. FST outlier analyses highlighted 12 loci associated with differentiation between mainland and island populations. Together these results suggest that the island populations examined are on independent evolutionary trajectories, the traits considered have a genetic basis (rather than phenotypic variation being solely due to phenotypic plasticity). Coupled with the previous results showing significant phenotypic differentiation between island and mainland groups in this system, this study suggests that the ISH can hold even on a small spatial scale.</p>
Data from: Botfly infections impair the aerobic performance and survival of montane populations of deer mice, Peromyscus maniculatus rufinus
Open the record for dataset details and reuse information.
Data from: Genetic impacts of Anacapa deer mice reintroductions following rat eradication
Open the record for dataset details and reuse information.
Linking genetic, morphological, and behavioural divergence between inland island and mainland deer mice
Open the record for dataset details and reuse information.
Data from: Two pup vocalization types are genetically and functionally separable in deer mice
Open the record for dataset details and reuse information.
Data from: Microsatellite genetic structure and cytonuclear discordance in naturally fragmented populations of deer mice (Peromyscus maniculatus)
Open the record for dataset details and reuse information.
Data from: Development of homeothermic endothermy is delayed in high altitude native deer mice (Peromyscus maniculatus)
Open the record for dataset details and reuse information.
The genetics of morphological and behavioural island traits in deer mice
Open the record for dataset details and reuse information.
Data from: Whole mitochondrial genomes provide increased resolution and indicate paraphyly in deer mice
Open the record for dataset details and reuse information.
Data from: Maladaptive phenotypic plasticity in cardiac muscle growth is suppressed in high-altitude deer mice
Open the record for dataset details and reuse information.
Evolution of gene expression across brain regions in behaviorally divergent deer mice
GEO Series GSE245182. Peromyscus maniculatus x Peromyscus polionotus; Peromyscus maniculatus; Peromyscus polionotus. 191 samples. Type: Expression profiling by high throughput sequencing.
Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice
GEO Series GSE272719. Peromyscus maniculatus; Peromyscus polionotus. 6 samples. Type: Expression profiling by high throughput sequencing.
Geographic variation in epigenetic responses to hypoxia in deer mice (Peromyscus maniculatus) distributed along an elevational gradient
GEO Series GSE270202. Peromyscus maniculatus. 39 samples. Type: Methylation profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.