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98 results for “elongation factor”

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zenodo36/100

Supporting data for "Dynamics of RNA polymerase II and elongation factor Spt4/5 recruitment during activator-dependent transcription"

<p>Supporting data for</p> <p><strong>Dynamics of RNA polymerase II and elongation factor Spt4/5 recruitment</strong></p> <p><strong>during activator-dependent transcription </strong></p> <p>Grace A. Rosen<sup>a,1</sup>, Inwha Baek<sup>b,1</sup>, Larry J. Friedman<sup>a</sup>, Yoo Jin Joo<sup>b</sup>, Stephen Buratowski<sup>b,2</sup>, Jeff Gelles<sup>a,2</sup></p> <p><sup>a</sup>Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02454, USA.</p> <p><sup>b</sup>Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.</p> <p><sup>1</sup>Equal contributions</p> <p><sup>2</sup>Corresponding authors:&nbsp; <a href="mailto:steveb@hms.harvard.edu">steveb@hms.harvard.edu</a>; +1 (617) 432-0696 (S.B.) and <a href="mailto:gelles@brandeis.edu">gelles@brandeis.edu</a>; +1 (781) 736-2377 (J.G.)</p> <p>See <strong>Source data index.pdf</strong> for description of files.</p>

opencc-by-4.0Oct 2020View details →
ClinicalTrials.gov36/100

Autologous CD34+ Hematopoietic Stem Cells Transduced ex Vivo With Elongation Factor 1 Alpha Shortened (EFS) Lentiviral Vector Encoding for the Human ADA Gene

ClinicalTrials.gov study NCT01852071. IPD Sharing: Not stated. Countries: 1. Publications: 3.

restrictedIPD-UNDECIDEDFeb 2026View details →
zenodo32/100

ROS and SGI data for manuscript "The perception and evolution of flagellin, cold shock protein, and elongation factor Tu from vector-borne bacterial plant pathogens"

<p>This contains raw data for the ROS and seedling growth inhibition (SGI) assays collected for the manuscript "The perception and evolution of flagellin, cold shock protein, and elongation factor Tu from vector-borne bacterial plant pathogens". For a quick reference, there are two spreadsheets listing all the Max RLUs and Z-scores for the experiments, but the actual output of each plate reader is also included.&nbsp;</p>

opencc-by-4.0May 2024View details →
zenodo32/100

Predictive model of transcriptional elongation control identifies trans regulatory factors from chromatin signatures

<p>Supplementary data for &quot;Predictive model of transcriptional elongation control identifies trans regulatory factors from chromatin signatures&quot; by Toray S. Akcan, Matthias Heinig.</p>

opencc-by-4.0Oct 2021View details →
zenodo32/100

Dataset for in silico study of Exotoxin A - Elongation Factor 2 interaction

<p>BPMD:&nbsp; Binding Pose Metadynamics simulations of ETA with 3 different ligands (NAD+,bTAD, and ADP-ribose).&nbsp;</p> <p>ETA: 200 ns MD simulation trajectories for ETA with 3 different ligands (NAD+,bTAD, and&nbsp;ADP-ribose)&nbsp;in 3 replicas.</p> <p>ETA_EF2_Complexes: 200 ns MD simulation trajectories exploring the interaction between ETA&nbsp; and EF2 with 3 different ligands (NAD+, bTAD, and ADP-ribose non-bonded) in 3 replicas with DTA715 or HIS715 containing eEF2.</p> <p>ETA_EF2_ADP_ribose-Bonded: 200 ns MD simulation trajectories exploring the interaction between ETA and&nbsp;DTA715-containing eEF2 with ADP-ribose covalently bound to DTA715. 3 replicas.</p>

opencc-by-4.0Aug 2022View details →
geo24/100

Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [ATAC-seq]

GEO Series GSE225993. Homo sapiens; Mus musculus. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenMar 2024View details →
geo24/100

Negative Elongation Factor (NELF) regulation of muscle progenitor expansion assessed via Precision Run-On Sequencing (PRO-seq)

GEO Series GSE149766. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenApr 2021View details →
geo24/100

Involvement of transcription elongation factor GreA in Mycobacterium tuberculosis viability, antibiotic susceptibility, and intracellular fitness

GEO Series GSE143764. Mycolicibacterium smegmatis MC2 155. 10 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJan 2020View details →
geo24/100

CHD1 in yeast is recruited by transcription elongation factors and maintains H3K4me3/H3K36me3 domains at actively transcribed and spliced genes

GEO Series GSE90998. Saccharomyces cerevisiae. 27 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenApr 2017View details →
geo24/100

Negative Elongation Factor (NELF) regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation [RNA-seq]

GEO Series GSE150277. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2021View details →
geo24/100

RNA-seq of GM15850 and GM15851 cells treated with synthetic transcription elongation factors.

GEO Series GSE99400. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2017View details →
geo24/100

Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [nascent RNAseq]

GEO Series GSE226000. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2024View details →
geo24/100

Selective expression of the transcription elongation factor Eleven Nineteen Lysine-rich Leukemia 3 (ELL3) in actiavted B lymphocytes drives rapid B cell proliferation

GEO Series GSE102360. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenDec 2017View details →
geo24/100

The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A)

GEO Series GSE93133. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenJan 2017View details →
geo24/100

Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes

GEO Series GSE136091. Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing; Other.

openGEO-OpenMay 2020View details →
geo24/100

The RNA Pol II Elongation Factor Ell3 Marks Enhancers in ES Cells and Primes Future Gene Activation

GEO Series GSE38148. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenDec 2012View details →
geo24/100

Transcription elongation factors are in vivo-specific cancer dependencies in glioma

GEO Series GSE74529. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenApr 2017View details →
geo24/100

The negative elongation factor NELF promotes active transcription of Drosophila ecdysone-dependent genes

GEO Series GSE156847. Drosophila melanogaster. 53 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenJan 2021View details →
geo24/100

RNA-seq Profiles in Transcription elongation factors are in vivo-specific cancer dependencies in glioma

GEO Series GSE74516. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2017View details →
geo24/100

CHD1 in yeast is recruited by transcription elongation factors and maintains H3K4me3/H3K36me3 domains at actively transcribed and spliced genes [RNA-seq]

GEO Series GSE90997. Saccharomyces cerevisiae. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2017View details →

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

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neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

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behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record