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Inter-Chemical Correlation results for the study: HHEARx2018-2512 (The Role of Environmental Endocrine Disruptors on the Health of Inner City Children)

Title: The Role of Environmental Endocrine Disruptors on the Health of Inner City Children Species: Homo sapiens Number of samples: 651 Number of named analytes: 26 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=62

Inter-Chemical Correlation results for the study: HHEARx2018-2120 (The impact of tobacco smoke exposure and environmental exposures on the pulmonary microbiome and outcomes of critically ill children)

Title: The impact of tobacco smoke exposure and environmental exposures on the pulmonary microbiome and outcomes of critically ill children Species: Homo sapiens Number of samples: 1090 Number of named analytes: 12 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=42

Inter-Chemical Correlation results for the study: HHEARx2017-1945 (Maternal and Developmental Risks from Environmental and Social Stressors (MADRES))

Title: Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) Species: Homo sapiens Number of samples: 421 Number of named analytes: 21 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=32

Inter-Chemical Correlation results for the study: HHEARx2018-2532 (Environmental Toxins in Early Life: Shaping Health and Disease in Childhood)

Title: Environmental Toxins in Early Life: Shaping Health and Disease in Childhood Species: Homo sapiens Number of samples: 1147 Number of named analytes: 48 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=69

Inter-Chemical Correlation results for the study: HHEARx2017-1598 (Evaluation of Environmental Exposures in TEDDY)

Title: Evaluation of Environmental Exposures in TEDDY Species: Homo sapiens Number of samples: 1025 Number of named analytes: 45 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=37

Inter-Chemical Correlation results for the study: HHEARx2017-1593 (Role of environmental toxicants in modulating disease severity in children with NAFLD)

Title: Role of environmental toxicants in modulating disease severity in children with NAFLD Species: Homo sapiens Number of samples: 436 Number of named analytes: 7 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=30

Inter-Chemical Correlation results for the study: HHEARx2016-1461 (ECHO ReCHARGE Study - Environmental Exposures)

Title: ECHO ReCHARGE Study - Environmental Exposures Species: Homo sapiens Number of samples: 1231 Number of named analytes: 75 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=17

opencc-zeroJun 2024View details →

Inter-Chemical Correlation results for the study: HHEARx2016-1432 (Micronutrient deficiencies, environmental exposures and severe malaria: Risk factors for adverse neurodevelopmental outcomes in Ugandan children)

Title: Micronutrient deficiencies, environmental exposures and severe malaria: Risk factors for adverse neurodevelopmental outcomes in Ugandan children Species: Homo sapiens Number of samples: 1256 Number of named analytes: 51 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=5

Inter-Chemical Correlation results for the study: HHEARx2017-1839 (Zika Virus Congenital Health Outcomes and the Impact of Maternal Environmental Exposures)

Title: Zika Virus Congenital Health Outcomes and the Impact of Maternal Environmental Exposures Species: Homo sapiens Number of samples: 2705 Number of named analytes: 10 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=61

opencc-zeroJun 2024View details →

Inter-Chemical Correlation results for the study: HHEARx2016-1449 (Environmental phenols and pesticide levels in relationship to autism)

Title: Environmental phenols and pesticide levels in relationship to autism Species: Homo sapiens Number of samples: 842 Number of named analytes: 28 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=7

opencc-zeroJun 2024View details →

Inter-Chemical Correlation results for the study: HHEARx2016-1407 (Pediatric Inner-City Environmental Exposures at School and Home and Asthma Study)

Title: Pediatric Inner-City Environmental Exposures at School and Home and Asthma Study Species: Homo sapiens Number of samples: 157 Number of named analytes: 28 Datasource url: https://hheardatacenter.mssm.edu/PublicFile/ViewPublicFile?projectid=2

Fig. 4 in Silk Spinning Behavior Varies from Species-Specific to Individualistic in Embioptera: Do Environmental Correlates Account for this Diversity?

Fig. 4. Computation of similarity between two sequences. For two individuals of Aposthonia borneensis (Hagen) (Oligotomidae), the first 500 steps of their spin sequences are shown (A and B).The red bar underlining a short sequence indicates one 15-step subsequence that is highly similar between these two individuals. For all possible pairs of 15 step subsequences, the heatmap displays the sequence similarity (C), with red areas indicating regions of the spin sequence that are highly similar.The profiles on the margins of the heat map indicate the marginal maxima—that is, for each 15-step subsequence, what is the similarity to the most similar subsequence in the other individual. Portions of the sequence with similarities about 12 were deemed sufficiently similar to the other sequence (vertical or horizontal lines), amounting to about 5% of individual 1's sequence and 10% of individual 2's sequence.

Fig. 3 in Silk Spinning Behavior Varies from Species-Specific to Individualistic in Embioptera: Do Environmental Correlates Account for this Diversity?

Fig. 3. Kinematic diagrams displaying relative proportion of spin-steps in each position as relative size of the circles. Saturated black color of the body represents dorsal spinning; dark gray represents kinematics when the embiopteran faces the framework silk and spins with her ventral surface facing the camera and the emerging silk structure. Spinning was recorded during hour-long filming sessions in the laboratory in an apparatus as shown in Supp Fig. 1 [online only]. (A) Notoligotoma hardyi average spin dynamics, (B) Haploembia tarsalis average spin dynamics, (C) Diagram shows the positions of the different possible spinsteps whereby the words are placed in the position of the front foot as the embiopteran steps around her body to release silk with each foot fall.The same steps are taken on the left as well during spinning. See Supp Video 2 [online only] for examples of spinning behavior exhibited by individual females.

Fig. 5 in Silk Spinning Behavior Varies from Species-Specific to Individualistic in Embioptera: Do Environmental Correlates Account for this Diversity?

Fig. 5. Phylogenetic relationships and sequence similarities (n = 15) for all individuals in this study. (A) Sequence similarities are depicted as a heat map, with the diagonal representing self-similarities.The small outlined boxes along the diagonal indicate all intraspecific comparisons, and the mean intraspecific similarity for each species is depicted above the heat map. For comparison, the inset graph, (B) shows the similarity among pairs of species for a trait that is evolving according to the Ornstein-Uhlenbeck model.The large clade constituting the top 19 species shows high similarity among species (mostly dark colors in the upper left), but low similarity to the two outgroups to this clade (bottom six species, shows as lighter gray colors).The phylogenetic tree is based on Miller et al. 2012.

Fig. 7 in Silk Spinning Behavior Varies from Species-Specific to Individualistic in Embioptera: Do Environmental Correlates Account for this Diversity?

Fig. 7. Predictors of intraspecific similarity scores. The three panels show the partial residual plots for the three variables selected in the final model for a subsequence length of 15. Intraspecific similarity as a function of: (A) mean annual temperature, (B) temperature seasonality, and (C) silk gallery structure. Two-letter codes indicate the species as in Fig. 6.

opencc-zeroJul 2020View details →

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Data from: Genetic and environmental canalization are not correlated among altitudinally varying populations of Drosophila melanogaster

Organisms are exposed to environmental and mutational effects influencing both mean and variance of phenotypes. Potentially deleterious effects arising from this variation can be reduced by the evolution of buffering (canalizing) mechanisms, ultimately reducing phenotypic variability. There has been interest regarding the conditions enabling the evolution of canalization. Under some models, the circumstances under which genetic canalization evolves is limited, despite apparent empirical evidence for it. It has been argued that genetic canalization evolves as a correlated response to environmental canalization (congruence model). Yet, empirical evidence has not consistently supported predictions of a correlation between genetic and environmental canalization. In a recent study, a population of Drosophila adapted to high altitude showed evidence of genetic decanalization relative to those from low altitudes. Using strains derived from these populations, we tested if they varied for multiple aspects of environmental canalization We observed the expected differences in wing size, shape, cell (trichome) density and mutational defects between high- and low-altitude populations. However, we observed little evidence for a relationship between measures of environmental canalization with population or with defect frequency. Our results do not support the predicted association between genetic and environmental canalization.

FIGURE 2 in Environmental correlates of the European common toad hybrid zone

FIGURE 2 Two-species 'global' distribution model for Bufo toads in western Europe. The colour scale runs from deep red for B. spinosus (Pb is zero) to deep blue for B. bufo (Pb at unity). The interrupted black line represents the center of the species' hybrid zone from molecular data, as in fig. 1. Outlined circular windows are those for which model fit is less than good (AUC <0.8, windows 1, 6–8 and 14–16).

FIGURE 3 in Environmental correlates of the European common toad hybrid zone

FIGURE 3 Two regions in the common–spined toad hybrid zone where the mutual species border appears to coincide with rivers. Coloured dots indicate toad populations with nuclear genetic species identifications as Bufo bufo (Q = Pb> 0.5, blue symbols) and B. spinosus (Q = Pb <0.5, red symbols). Open dots have Q-values in the 0.2–0.8 range. For numerical detail see supplementary table S1. Base map figure credits as in fig. 1. A) central France where the species border appears to coincide with the northern- most sections of the Loire (windows 5 and 6) and the upper stretches of the Cher (windows 7 and 8). B) southeastern France where the species border coincides with the Rhône and the lower Isère river at window 13. Note the paucity of data for the high Alps at windows 15 and 16 (see also Lescure and de Downloaded from Brill.com 12/12/2023 03:07:30PM Massary, 2012; Arntzen et al., via2017Open). Access. This is an open access article distributed under the terms of the CC-BY 4.0 License. https://creativecommons.org/licenses/by/4.0/

FIGURE 1 in Environmental correlates of the European common toad hybrid zone

FIGURE 1 Western Europe with France and adjacent countries in Mercator projection. Colours from green to brown indicate increasing altitudes. The Bufo bufo versus B. spinosus mutual range delineation is based upon molecular genetic data, in which the smooth interrupted line is derived by linear interpolation whereas the more angular line is based upon Dirichlet cells (for details see text). The small bodied common toad B. bufo occurs to the northeast and the large bodied spined toad B. spinosus to the southwest of the mutual range border. Environmental data were gathered for 17 overlapping and adjoining circular windows positioned over the mutual range border. Here shown are window 1 in the northwest of France, window 17 in the northwest of Italy and windows 5, 9 and 13 in between. The two boxed areas are highlighted in fig. 3. The base map was downloaded from MapsLand at https://www.mapsland.com, under a Creative Commons Attribution-ShareAlike 3.0 Licence. The animal drawings are by Bas Blankevoort, Naturalis Biodiversity Center.

FIGURE 4 Average values for eight environmental variables over 17 windows that follow the Bufo bufo – B in Environmental correlates of the European common toad hybrid zone

FIGURE 4 Average values for eight environmental variables over 17 windows that follow the Bufo bufo – B. spinosus hybrid zone from the Atlantic coast (window 1) to the Mediterranean (window 17). Variables shown are those selected by a logistic regression analysis, with 'species' as dependent variable and explanatory variables available for selection as in table 1. Units are as in table 1; see also Hijmans et al. (2005). Values for B. bufo and B. spinosus are shown by small and large dots, respectively. Grey areas indicate that values for B. bufo are lower than for B. spinosus. The graph at the top left provides AUC model fit values along with major topographical references. Rectangles indicate stretches of the species contact for which the environmental models have good fit (AUC> 0.8), with consistent results indicated by green shadings. For the other windows with less than good model fit, signals are likely to be absent or void, either from poor sampling (window 1), the presence of rivers (windows 5–9, 13–14), or a thin or absent species' contact (windows 16–17) (see fig. 3).