Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
25
datasets available to search
ShareScore release 0.9.0
Dataset results
25 results for “gastrointestinal microbiome”
Microbiome profile of patients in a referral gastrointestinal diseases centre in the Sudan
<p>Data set of 16S rRNA Nanopore sequencing of DNA extracted from faecal samples of Gastrointestinal tract diseases from Human. </p>
MERFISH measurements of the mouse gastrointestinal tract in the presence and absence of the microbiome
Open the record for dataset details and reuse information.
Data from: Nasopharyngeal microbiome profiles in rural Venezuelan children are associated with respiratory and gastrointestinal infections
<p>Background: Recent research suggests that the microbiota affects susceptibility to both respiratory tract infections (RTIs) and gastrointestinal infections (GIIs). In order to optimize global treatment options, it is important to characterize microbiota profiles across different niches and geographic/socioeconomic areas where RTI and GII prevalences are high.</p> <p>Methods: We performed 16S sequencing of nasopharyngeal swabs from 209 Venezuelan Amerindian children aged 6 weeks–59 months who were participating in a 13-valent pneumococcal conjugate vaccine (PCV13) study. Using random forest models, differential abundance testing, and regression analysis, we determined whether specific bacteria were associated with RTIs or GIIs and variation in PCV13 response.</p> <p>Results: Microbiota compositions differed between children with or without RTIs (P = .018) or GIIs (P = .001). Several species were associated with the absence of infections. Some of these health-associated bacteria are also observed in developed regions, such as Corynebacterium (log2(fold change [FC]) = 3.30 for RTIs and log2(FC) = 1.71 for GIIs), while others are not commonly observed in developed regions, such as Acinetobacter (log2(FC) = 2.82 and log2(FC) = 5.06, respectively). Klebsiella spp. presence was associ- ated with both RTIs (log2(FC) = 5.48) and GIIs (log2(FC) = 7.20).</p> <p>Conclusions: The nasopharyngeal microbiota of rural Venezuelan children included several bacteria that thrive in tropical humid climates. Interestingly, nasopharyngeal microbiota composition not only differed in children with an RTI but also in those with a GII, which suggests a reciprocal interplay between the 2 environments. Knowledge of region-specific microbiota patterns enables tailoring of preventive and therapeutic approaches.</p>
Table S1 - Table S7: Integrated meta-omic analyses of the gastrointestinal tract microbiome in patients undergoing allogeneic stem cell transplantation
<p> </p> <p><strong>Table S1. </strong>Number of reads per prokaryotic operational taxonomic unit (OTU) and sample from the cohort.<strong> </strong></p> <p><strong>Table S2. </strong>Number of reads per eukaryotic operational taxonomic unit (OTU) and sample from the cohort.</p> <p><strong>Table S3. </strong>Blood cell counts and clinical data from patient A07.<strong> </strong></p> <p><strong>Table S4. </strong>Number of reads per operational taxonomic unit (OTU) and sample from patient A07.<strong> </strong></p> <p><strong>Table S5. </strong>Numbers of identified antibiotic resistance genes and total number of genes. Numbers of identified antibiotic resistance genes in relation to total numbers of genes in samples from patient A07 before and after allo-HSCT and from four healthy individuals.<strong> </strong></p> <p><strong>Table S6. </strong>Statistics of the metagenomic and metatranscriptomic datasets and the co-assembled contigs.<strong> </strong></p> <p><strong>Table S7. </strong>Antibiotic resistance genes in population-level genomes and their expression in the pre- and post-treatment sample.</p>
Gastrointestinal Microbiome Influence on the Development of Bronchopulmonary Dysplasia
ClinicalTrials.gov study NCT03229967. IPD Sharing: NO. Countries: 1. Publications: 1.
Gastrointestinal Tract Microbiome in Healthy Term Infants Receiving Mother'S-own Breast Milk or Cow's Milk-based Infant Formulas
ClinicalTrials.gov study NCT04059666. IPD Sharing: NO. Countries: 1. Publications: 1.
The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies
ClinicalTrials.gov study NCT06072976. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Exploratory Study of the Microbiome of Upper Gastrointestinal in the Pathogenesis of Multiple Primary Lung Cancer
ClinicalTrials.gov study NCT06973499. IPD Sharing: NO. Countries: 1. Publications: 1.
Gastrointestinal Microbiome Study of Appendiceal Cancer
ClinicalTrials.gov study NCT02599116. IPD Sharing: NO. Countries: 1. Publications: 1.
The Effects of Soluble Corn Fiber on Gastrointestinal Tolerance and Fecal Microbiome in Healthy Children
ClinicalTrials.gov study NCT05213494. IPD Sharing: NO. Countries: 1. Publications: 13.
The Gastrointestinal Microbiome of Infants With GERD and PPI Therapy: a Pilot Study
ClinicalTrials.gov study NCT02359604. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Data from: Faecal inoculations alter the gastrointestinal microbiome and allow dietary expansion in a wild specialist herbivore, the koala
Open the record for dataset details and reuse information.
Data from: Nasopharyngeal microbiome profiles in rural Venezuelan children are associated with respiratory and gastrointestinal infections
Open the record for dataset details and reuse information.
Gut Microbiome & Gastrointestinal Toxicities as Determinants of Response to Neoadjuvant Chemo for Advanced Breast Cancer
ClinicalTrials.gov study NCT02696759. IPD Sharing: YES. Countries: 1. Publications: 0.
Gastrointestinal and Urinary Tract Microbiome After SCI
ClinicalTrials.gov study NCT02903472. IPD Sharing: NO. Countries: 5. Publications: 0.
VITORA: Clinical Study to Evaluate the Effect of KB109 on the Gut Microbiome in Subjects Whose Gastrointestinal Tracts Are Colonized With Multiple Drug-resistant Organisms
ClinicalTrials.gov study NCT03944369. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Probiotics Supplementation and Intestinal Microbiome in Neonates With Gastrointestinal Surgery
ClinicalTrials.gov study NCT03266315. IPD Sharing: NO. Countries: 1. Publications: 0.
Intestinal Microbiome, Oral Microbiome, and Whole Blood Transcriptome Analyses in Gastrointestinal Malignancies
ClinicalTrials.gov study NCT05462314. IPD Sharing: NO. Countries: 1. Publications: 0.
Effects of a Mushroom Blend on Gastrointestinal Symptoms and the Microbiome
ClinicalTrials.gov study NCT07027462. IPD Sharing: NO. Countries: 1. Publications: 0.
The Impact of Commercial Blenderized Formula on Caloric Needs, Gastrointestinal Symptoms, and Gut Microbiome in Children With Cerebral Palsy (CP)
ClinicalTrials.gov study NCT06488560. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.