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125 results for “glycemic index”
Maternal Dietary Glycemic Index and Glycemic Load in Pregnancy and Offspring Cord Blood DNA Methylation
<p><strong>Abstract</strong></p> <p><strong>Objective</strong>: Suboptimal nutrition in pregnancy is associated with worse offspring cardiometabolic health. DNA methylation may be an underlying mechanism. We meta-analyzed epigenome-wide association studies (EWASs) of maternal dietary glycemic index and load with cord blood DNA methylation.</p> <p><strong>Research Design and Methods</strong>: We calculated maternal glycemic index and load from food frequency questionnaires, and ran EWASs on cord blood DNA methylation in 2003 mother-offspring pairs from three cohorts. Analyses were additionally stratified by maternal BMI categories. We looked-up the findings in EWASs of maternal glycemic traits and BMI, and in EWASs of birthweight and child BMI. We examined associations with gene expression in child blood in the online Human Early Life Exposome eQTM catalogue and in 223 adipose tissue samples.</p> <p><strong>Results</strong>: Maternal glycemic index and load were associated with cord blood DNA methylation at 41 cytosine-phosphate-guanine sites (CpGs, P<1.17x10<sup>-7</sup>), mostly in mothers with overweight/obesity. We did not observe overlap with CpGs associated with maternal glycemic traits, BMI or child birthweight or BMI. Only DNA methylation at cg24458009 and cg23347399 was associated with expression of <em>PCED1B</em> and <em>PCDHG</em>, respectively, in child blood, and DNA methylation at cg27193519 was associated with expression of <em>TFAP4</em>, <em>ZNF500</em>, <em>PPL</em> and <em>ANKS3</em> in child subcutaneous adipose tissue.</p> <p><strong>Conclusions</strong>: We observed multiple associations of maternal glycemic index and load during pregnancy with cord blood DNA methylation, mostly in mothers with overweight/obesity; some of these CpGs were associated with gene expression. Additional studies are required to further explore functionality, uncover causality, and study pathways to offspring health.</p>
Glycemic Index of Date Cultivars and Date-based Products
ClinicalTrials.gov study NCT07286981. IPD Sharing: NO. Countries: 1. Publications: 1.
Low Glycemic Index Diets vs. High Cereal Fibre Diets in Type 2 Diabetes
ClinicalTrials.gov study NCT00438698. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Providing Personally Tailored Dietary Suggestions Using Individual Microbiome and Glycemic Index Response.
ClinicalTrials.gov study NCT02945514. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Effect of the Glycemic Index of Diet on Metabolic and Reproductive Parameters in Overweight and Obese Infertile Women
ClinicalTrials.gov study NCT02416960. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Reduction of the Glycemic Index by a Novel Viscous Polysaccharide
ClinicalTrials.gov study NCT00935350. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Glycemic Index of Mango and Pear in Different Solid Products and Drinks
ClinicalTrials.gov study NCT01929551. IPD Sharing: Not stated. Countries: 1. Publications: 27.
Low Glycemic Index Dietary Intervention Program in Nonalcoholic Fatty Liver Disease
ClinicalTrials.gov study NCT00868933. IPD Sharing: Not stated. Countries: 1. Publications: 16.
Acute Studies on the Glycemic Index After Intake of Different Sorts of Barley in Subjects With Type 2 Diabetes
ClinicalTrials.gov study NCT04646746. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Lysine and Phosphorus Fortification on Glycemic Index and Postprandial Glycemia in Double Fortified Bread
ClinicalTrials.gov study NCT05903625. IPD Sharing: NO. Countries: 1. Publications: 6.
Determination of Glycemic Index and Glycemic Load of Cereal Fiber Powder
ClinicalTrials.gov study NCT05143060. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Glycemic Index and Polyphenol Bioavailability of Potatoes
ClinicalTrials.gov study NCT01053793. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Low Glycemic Index Diet (With Canola Oil) for Type 2 Diabetics
ClinicalTrials.gov study NCT01348568. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of a High Protein and Low Glycemic Index Diet on Kidney Transplant Recipients
ClinicalTrials.gov study NCT02883777. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Low Glycemic Index (GI) Diet Management for Pregnant Woman With Overweight
ClinicalTrials.gov study NCT01628835. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Low-Glycemic Index Mediterranean Diet on AGEs
ClinicalTrials.gov study NCT02353416. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Comparative Evaluation of Glycemic Index of Different Types of Jaggery Produced Locally in Pakistan
ClinicalTrials.gov study NCT07015814. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
The Effects of Low Glycemic Index (GI) Diet on Cardiometabolic Outcomes Among Obese Chinese Adults
ClinicalTrials.gov study NCT04152213. IPD Sharing: NO. Countries: 1. Publications: 1.
Glycemic Index - Variability Among Individuals
ClinicalTrials.gov study NCT01023646. IPD Sharing: Not stated. Countries: 1. Publications: 16.
Glycemic and Satiety Response to Fiber and Glycemic Index of Meals in Diabetes
ClinicalTrials.gov study NCT01410292. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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OpenNeuro
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