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28 results for “high-dimensional data”

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zenodo44/100

Data and Code for Publication "Estimating inter-individual Mahalanobis distances from mixed incomplete high-dimensional data: Application to human skeletal remains from 3rd to 1st millennia BC Southwest Germany"

<p>Data and code for publication: H. Rathmann, S. Lismann, M. Francken, A. Spatzier, Estimating inter-individual Mahalanobis distances from mixed incomplete high-dimensional data: Application to human skeletal remains from 3<sup>rd</sup> to 1<sup>st</sup> millennia BC Southwest Germany.&nbsp;<em>Journal of Archaeological Science</em> 156: 105802. <a href="https://doi.org/10.1016/j.jas.2023.105802">https://doi.org/10.1016/j.jas.2023.105802</a></p> <p>The repository contains:</p> <ul> <li>&ldquo;R code for FLEXDIST.txt&rdquo;: R code for executing FLEXDIST, a tool to estimate inter-individual Mahalanobis-type distances, taking correlations among variables into account, applicable to multiple variable scales (nominal, ordinal, continuous, or any mixture thereof), accommodating missing values, and handling high-dimensional data. <strong>Please refer to the latest version of this repository for the most up-to-date R code</strong>.</li> <li>&ldquo;data.csv&rdquo;: Pre-processed dataset comprising 85 dental morphological features collected from 64 archaeological human remains from Final Neolithic to Early Iron Age Southwest Germany used for analysis.</li> <li>&ldquo;complete dataset.xlsx&rdquo;: Complete dataset comprising 199 dental morphological features collected from 144 archaeological human remains from Final Neolithic to Early Iron Age Southwest Germany.</li> </ul>

opencc-by-4.0Apr 2023View details →
zenodo40/100

Data of "Bayesian inference of high-dimensional finite-strain visco-elastic-visco-plastic model parameters for additive manufactured polymers and neural network based material parameters generator"

<p><strong>General</strong></p> <p>Data of <a href="http://doi.org/10.1016/j.ijsolstr.2023.112470">https://doi.org/10.1016/j.ijsolstr.2023.112470</a> related to MOAMMM project.</p> <p>Data related to the publication (we would be grateful if you could cite the paper in the case in which you are using the data):</p> <p>title = &quot;Bayesian inference of high-dimensional finite-strain visco-elastic-visco-plastic model parameters for additive manufactured polymers and neural network based material parameters generator.&quot;,<br> journal = &quot;International Journal of Solids and Structures&quot;,<br> year = &quot;2023&quot;,<br> volume = &quot;283&quot;,<br> pages = &quot;112470&quot;,<br> doi = &quot;10.1016/j.ijsolstr.2023.112470&quot;,<br> author = &quot;Ling Wu, Cyrielle Anglade, Lucia Cobian, Miguel Monclus, Javier Segurado, Fatma Karayagiz, Ubiratan Freitas, and Ludovic Noels&quot;</p> <p>This project has received funding from the European Union&rsquo;s Horizon 2020 research and innovation programme under grant agreement No 862015. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union. Neither the European Union nor the granting authority can be held responsible for them.</p> <p><strong>Description</strong></p> <p>BI code and results of the inference of a pressure-dependent visco-elastic visco-plastic model developed in [NGU16] with a umat implementation in <a href="https://gitlab.uliege.be/moammm/moammmPublic/code/-/tree/main/MaterialModels/FiniteStrain/Finite_VEVP">https://gitlab.uliege.be/moammm/moammmPublic/code/-/tree/main/MaterialModels/FiniteStrain/Finite_VEVP</a>. The BI is described in [WU23] .The experimental results used in the BI are reported in [COB22,COB22b]. To run the BI you need the open source code <a href="https://gitlab.onelab.info/cm3/cm3Libraries">https://gitlab.onelab.info/cm3/cm3Libraries</a> If you use these data or model, we would be grateful if you could cite the related papers.</p> <p><strong>Bibliography</strong></p> <ul> <li>[WU23] L. Wu, C. Anglade, L. Cobian, M. Monclus, J. Segurado, F. Karayagiz, U. Santos Freitas, L. Noels, Bayesian inference of high-dimensional finite-strain visco-elastic-visco-plastic model parameters for additive manufactured polymers and neural network based material parameters generator, International Journal of Solids and Structures (2023) 112470: https://doi.org/10.1016/j.ijsolstr.2023.112470</li> <li>[COB22] L. Cobian, M. Rueda-Ruiz, J.P. Fernandez-Blazquez, V. Martinez, F. Galvez, F. Karayagiz, T. L&uuml;ck, J. Segurado, M.A. Monclus, Micromechanical characterization of the material response in a PA12-SLS fabricated lattice structure and its correlation with bulk behaviour, Polymer Testing 110 (2022) 107556: https://doi.org/10.1016/j.polymertesting.2022.107556 (in Open access)</li> <li>[COB22b] Data of &ldquo;. Cobian, M. Rueda-Ruiz, J.P. Fernandez-Blazquez, V. Martinez, F. Galvez, F. Karayagiz, T. L&uuml;ck, J. Segurado, M.A. Monclus, Micromechanical characterization of the material response in a PA12-SLS fabricated lattice structure and its correlation with bulk behaviour, Polymer Testing 110 (2022) 107556&rdquo; http://dx.doi.org/10.5281/zenodo.6136935 (in Open access)</li> <li>[NGU16] V. D. Nguyen, F. Lani, T. Pardoen, X. Morelle, L. Noels, A large strain hyperelastic viscoelastic-viscoplastic-damage constitutive model based on a multi-mechanism non-local damage continuum for amorphous glassy polymers. International Journal of Solids and Structures 96 (2016): 192-216; https://dx.doi.org/10.1016/j.ijsolstr.2016.06.008, Open access: https://orbi.uliege.be/handle/2268/197898</li> </ul> <p><strong>Directories</strong></p> <p>All the codes and experimental results are in five directories:</p> <ol> <li>experimentalTests: experimental data, see the README.txt in each subdirectory for details</li> <li>BayesianVE: BI of the visco-elastic parameters <ol> <li>PlotExperimentalCurves: to vizualize the experimental curves and prepare the observations for the BI in the VE range <ol> <li>Loadcase_H.py and Loadcase_V.py read experimental results and create Load_ExpVE_H.dat and Load_ExpVE_V.dat, which keep the experimental observations and loading conditions to perform the BI.</li> <li>PrintDir_H &amp; PrintDir_V subdirectories with the functions called by Loadcase_H.py and Loadcase_V.py</li> <li>Load_ExpVE_H.dat and Load_ExpVE_V.dat created files with the observations and loading conditions to perform the BI</li> </ol> </li> <li>VE_V2Step and VE_H: BI for viscoelastic properties of &quot;V&quot; specimen (VE_V2Step) and &quot;H&quot; specimen (VE_H) <ol> <li>BI_allpos_sequence.py runs the BI using Predict_VETest.py and creates the MCMC_VE_....dat</li> <li>WarmStart = True is used to restart an inference</li> <li>MCMC_VE_....dat in the VE_V2Step and VE_H directories are the BI results</li> <li>When proceeding in two steps in VE_V2Step, a first step generates MCMC_VE_VN8_1st.dat whose posterior is used as prior in the second step to generate MCMC_VE_VN8_2nd.dat</li> </ol> </li> <li>CheckBayRes: to visualize predictions of a BI sample and experimental curves <ol> <li>MCMCRes.py is used to check the numerical predictions of a BI parameter sample (read last sample by default, V or H direction can be selected at line</li> <li>ResKGEmu.py plots the evolution of elastic properties with time</li> <li>uses as input VE_V2Step/MCMC_VE_....dat or VE_H/MCMC_VE_....dat</li> <li>uses local ViscoElasticTest.py, line.geo, line. msh as interface with https://gitlab.onelab.info/cm3/cm3Libraries code</li> <li>uses local functions plotExpLoad_Unload.py, plotExp.py</li> </ol> </li> <li>ViscoElasticTest.py, line.geo, line.msh: interface with <a href="https://gitlab.onelab.info/cm3/cm3Libraries">https://gitlab.onelab.info/cm3/cm3Libraries</a> code used by VE_V2Step and VE_H to call the VEVP model</li> </ol> </li> <li>BayesianVEVP: BI of the visco-elastic and visco-plastic parameters <ol> <li>PlotExperimentalCurves: to vizualize the experimental curves and prepare the observations for the BI in the VE-VP ranges <ol> <li>Loadcase_H.py and Loadcase_V.py read experimental results and create Load_ExpVEVP_H.dat and Load_ExpVEVP_V.dat, which keep the experimental observations and loading conditions to perform BI at the viscoplastic stage.</li> <li>PrintDir_H &amp; PrintDir_V subdirectories with the functions called by Loadcase_H.py and Loadcase_V.py</li> <li>Load_ExpVEVP_H.dat and Load_ExpVEVP_V.dat created files with the observations and loading conditions to perform the BI</li> </ol> </li> <li>VP_V2step and VP_H2step: BI for viscoelastic-viscoplastic properties of &quot;V&quot; specimen (VP_V2Step) and &quot;H&quot; specimen (VP_H2Step) <ol> <li>BI_allpos_sequence.py runs the BI using Predict_VETest.py and creates the MCMC_VP_....dat</li> <li>WarmStart = True is used to restart an inference</li> <li>It starts from the VE prosterior as prior, see point 2, and generates a MCMC_VP_?_1of2Steps.dat (? being H or V)</li> <li>Then using MCMC_VP_?_1of2Steps.dat posterior to get a new prior, it generates MCMC_VP_?_2of2Steps.dat (? being H or V)</li> </ol> </li> <li>CheckBayRes: visualize predictions of a BI sample and experimental curves <ol> <li>MCMCRes.py is used to check the numerical predictions with 3 BI parameter samples ([28000, 45000,70000] by default, V or H direction can be selected at line 12) using the samples of BayesianVEVP/VP_?2step/MCMC_VP_?_2of2Steps.dat (? being H or V)</li> <li>plot_hist.py is used to plot histograms of all the inferred parameters using the samples of BayesianVEVP/VP_?2step/MCMC_VP_?_2of2Steps.dat (? being H or V)</li> <li>Plot_Prop.py plots joints histograms of the inferred parameters using the samples of BayesianVEVP/VP_?2step/MCMC_VP_?_2of2Steps.dat (? being H or V)</li> <li>ResKGEmu.py plots the evolution of elastic properties with time</li> </ol> </li> <li>VEVPTest.py: interface with https://gitlab.onelab.info/cm3/cm3Libraries code used by VP_V2Step and VP_H2Step to call the VEVP model</li> </ol> </li> <li>RandomParametersGenerator: used to generate the parameters from the BI samples, with the same statistical content <ol> <li>Generator <ol> <li>DataProcess.py: creates normalized data for training from final inferred parameters in ../MCMC_ResData and creates ?_dirNormData (? being H or V)</li> <li>KmeanDataProcess.py: performs clustering for the data of H_dirNormDat and creates H_dirNormData_2cluster (no need for V direction because not bimodal)</li> <li>Gan_V.py and Gan_H.py are used to train the random material parameter generators and create the VDir_Gan or HDir_Gan200_0/HDir_Gan200_1</li> <li>GenerateParameters.py generates random parameters using the Gan files VDir_Gan or HDir_Gan200_0/HDir_Gan200_1 and checks the joint histograms of generated parameters, generated parameters are in V_GenData and H_GenData</li> <li>Ganlib.py is used by the generator</li> </ol> </li> <li>CheckRes <ol> <li>GenDataRes.py is used to check the numerical predictions with the generated parameter samples, see point 4) (using V_GenData and H_GenData).</li> <li>Plot_PropGen.py plots joints histograms of the generated parameters using the samples of V_GenData or H_GenData</li> </ol> </li> </ol> </li> <li>MCMC_ResData:All final data used in the paper (they can substitute the ones used here above) <ol> <li>H_direction and V_direction keep the MCMC random walk results of BI.</li> <li>RandomParameterGenerator keeps results of the generator Paper</li> </ol> </li> </ol> <p><strong>Figures of [WU23]</strong></p> <ul> <li>Fig. 5: From directory BayesianVE/PlotExperimentalCurves, run python3 ./PrintDir_V/plotExp_T.py or ./PrintDir_V/plotExp_C.py or ./PrintDir_V/plotExp_R.py</li> <li>Fig. 7: BayesianVEVP/CheckBayRes/Plot_Prop.py with direct = &quot;V&quot; and then with direct = &quot;H&quot; and with Var = [0,1,20,24,28,29,30,31]</li> <li>Fig. 8: BayesianVEVP/CheckBayRes/MCMCRes.py with direct = &quot;V&quot; (requires <a href="https://gitlab.onelab.info/cm3/cm3Libraries">https://gitlab.onelab.info/cm3/cm3Libraries</a> code)</li> <li>Fig. 9: BayesianVEVP/CheckBayRes/MCMCRes.py with direct = &quot;H&quot; (requires<a href="https://gitlab.onelab.info/cm3/cm3Libraries"> https://gitlab.onelab.info/cm3/cm3Libraries</a> code)</li> <li>Fig. 11: RandomParametersGenerator/CheckRes/Plot_PropGen.py with direct = &quot;V&quot; and then with direct = &quot;H&quot; and with Var = [0,1,20,24,28,29,30,31]</li> <li>Fig. 12: RandomParametersGenerator/CheckRes/GenDataRes.py with direct = &quot;V&quot; (requires <a href="https://gitlab.onelab.info/cm3/cm3Libraries">https://gitlab.onelab.info/cm3/cm3Libraries</a> code)</li> <li>Fig. 13: RandomParametersGenerator/CheckRes/GenDataRes.py with direct = &quot;H&quot; (requires <a href="https://gitlab.onelab.info/cm3/cm3Libraries">https://gitlab.onelab.info/cm3/cm3Libraries</a> code)</li> <li>Fig. 14A: From directory BayesianVE/PlotExperimentalCurves, run python3 ./PrintDir_H/plotExp_T.py or ./PrintDir_H/plotExp_C.py or ./PrintDir_H/plotExp_R.py</li> <li>Fig. 15C: BayesianVEVP/CheckBayRes/Plot_Prop.py with direct = &quot;V&quot;, Var = [2,3,8,9,14,15,18,19] and [20,21,22,23,24,25,26,27]</li> <li>Fig. 16C: BayesainVEVP/CheckBayRes/plot_hist.py with direct = &quot;V&quot;</li> <li>Fig. 17C: BayesianVEVP/CheckBayRes/plot_hist.py with direct = &quot;V&quot;</li> <li>Fig. 18C: BayesianVEVP/CheckBayRes/Plot_Prop.py with direct = &quot;H&quot;, Var = [2,3,8,9,14,15,18,19] and [20,21,22,23,24,25,26,27]</li> <li>Fig. 19C: BayesianVEVP/CheckBayRes/plot_hist.py with direct = &quot;H&quot;</li> <li>Fig. 20C: BayesianVEVP/CheckBayRes/plot_hist.py with direct = &quot;H&quot;</li> <li>Fig. 21D: RandomParametersGenerator/CheckRes/Plot_PropGen.py with direct = &quot;V&quot; , Var = [2,3,8,9,14,15,18,19] and [20,21,22,23,24,25,26,27]</li> <li>Fig. 22D: RandomParametersGenerator/CheckRes/Plot_PropGen.py with direct = &quot;H&quot; , Var = [2,3,8,9,14,15,18,19] and [20,21,22,23,24,25,26,27]</li> </ul> <p>&nbsp;</p> <p>&nbsp;</p>

opencc-by-4.0Apr 2023View details →
zenodo40/100

Research data supporting: "TimeSOAP: Tracking high-dimensional fluctuations in complex molecular systems via time variations of SOAP spectra"

<p>This repository contains the set of data shown in the paper&nbsp;<strong>&quot;<em>Time</em>SOAP: Tracking high-dimensional fluctuations in complex molecular systems via time variations of SOAP spectra&quot;</strong>, published on The Journal of Chemical Physics&nbsp;(DOI: 10.1063/5.0147025).</p>

opencc-by-4.0May 2023View details →
zenodo36/100

Raw data of high-dimensional aptamer selection generated by ProSELEX

<p>This is the raw selection dataset generated by ProSELEX pipeline (https://www.nature.com/articles/s41557-023-01207-z). The target of selection is human myeloperoxidase (MPO). See&nbsp;https://github.com/dwangnu/AptaZ for instructions.</p>

opencc-by-4.0Jul 2023View details →
dryad36/100

Data from: High-dimensional imaging of vestibular schwannoma reveals distinctive immunological networks across histomorphic niches in NF2-related schwannomatosis

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publicFeb 2025View details →
dryad32/100

Data from: A method for analysis of phenotypic change for phenotypes described by high-dimensional data

The analysis of phenotypic change is important for several evolutionary biology disciplines, including phenotypic plasticity, evolutionary developmental biology, morphological evolution, physiological evolution, evolutionary ecology and behavioral evolution. It is common for researchers in these disciplines to work with multivariate phenotypic data. When phenotypic variables exceed the number of research subjects—data called 'high-dimensional data'—researchers are confronted with analytical challenges. Parametric tests that require high observation to variable ratios present a paradox for researchers, as eliminating variables potentially reduces effect sizes for comparative analyses, yet test statistics require more observations than variables. This problem is exacerbated with data that describe 'multidimensional' phenotypes, whereby a description of phenotype requires high-dimensional data. For example, landmark-based geometric morphometric data use the Cartesian coordinates of (potentially) many anatomical landmarks to describe organismal shape. Collectively such shape variables describe organism shape, although the analysis of each variable, independently, offers little benefit for addressing biological questions. Here we present a nonparametric method of evaluating effect size that is not constrained by the number of phenotypic variables, and motivate its use with example analyses of phenotypic change using geometric morphometric data. Our examples contrast different characterizations of body shape for a desert fish species, associated with measuring and comparing sexual dimorphism between two populations. We demonstrate that using more phenotypic variables can increase effect sizes, and allow for stronger inferences.

opencc-zeroDec 2013View details →
zenodo32/100

Mass cytometry data for "High-dimensional mass cytometry reveals stemness state heterogeneity in pancreatic ductal adenocarcinoma"

<p>Raw suspension mass cytometry data supporting the publication "High-dimensional mass cytometry reveals stemness state heterogeneity in pancreatic ductal adenocarcinoma".</p>

opencc-by-4.0Mar 2024View details →
dryad32/100

Data from: Mapping beta diversity from space: Sparse Generalized Dissimilarity Modelling (SGDM) for analysing high-dimensional data

1. Spatial patterns of community composition turnover (beta diversity) may be mapped through Generalised Dissimilarity Modelling (GDM). While remote sensing data are adequate to describe these patterns, the often high-dimensional nature of these data poses some analytical challenges, potentially resulting in loss of generality. This may hinder the use of such data for mapping and monitoring beta-diversity patterns. 2. This study presents Sparse Generalised Dissimilarity Modelling (SGDM), a methodological framework designed to improve the use of high-dimensional data to predict community turnover with GDM. SGDM consists of a two-stage approach, by first transforming the environmental data with a sparse canonical correlation analysis (SCCA), aimed at dealing with high-dimensional datasets, and secondly fitting the transformed data with GDM. The SCCA penalisation parameters are chosen according to a grid search procedure in order to optimise the predictive performance of a GDM fit on the resulting components. The proposed method was illustrated on a case study with a clear environmental gradient of shrub encroachment following cropland abandonment, and subsequent turnover in the bird communities. Bird community data, collected on 115 plots located along the described gradient, were used to fit composition dissimilarity as a function of several remote sensing datasets, including a time series of Landsat data as well as simulated EnMAP hyperspectral data. 3. The proposed approach always outperformed GDM models when fit on high-dimensional datasets. Its usage on low-dimensional data was not consistently advantageous. Models using high-dimensional data, on the other hand, always outperformed those using low-dimensional data, such as single date multispectral imagery. 4. This approach improved the direct use of high-dimensional remote sensing data, such as time series or hyperspectral imagery, for community dissimilarity modelling, resulting in better performing models. The good performance of models using high-dimensional datasets further highlights the relevance of dense time series and data coming from new and forthcoming satellite sensors for ecological applications such as mapping species beta diversity.

opencc-zeroDec 2014View details →
zenodo32/100

High-dimensional multivariate autoregressive model estimation of human electrophysiological data using fMRI priors

<p>Data to reproduce figures in&nbsp;submitted&nbsp;manuscript &quot;High-dimensional multivariate autoregressive model estimation of<br> human electrophysiological data using fMRI priors&quot;</p> <p>https://www.biorxiv.org/content/10.1101/2022.11.18.516669v1</p>

opencc-by-sa-4.0Apr 2023View details →
dryad32/100

Data from: A method for analysis of phenotypic change for phenotypes described by high-dimensional data

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publicJun 2014View details →
dryad32/100

Data from: A method for assessing phylogenetic least squares models for shape and other high-dimensional multivariate data

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publicMay 2014View details →
dryad32/100

Data from: Mapping beta diversity from space: Sparse Generalized Dissimilarity Modelling (SGDM) for analysing high-dimensional data

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publicMar 2016View details →
dryad28/100

Data from: High-dimensional variance partitioning reveals the modular genetic basis of adaptive divergence in gene expression during reproductive character displacement

Although adaptive change is usually associated with complex changes in phenotype, few genetic investigations have been conducted of adaptations that involve sets of high dimensional traits. Microarrays have supplied high-dimensional descriptions of gene expression, and phenotypic change resulting from adaptation often results in large-scale changes in gene expression. We demonstrate how genetic analysis of large-scale changes in gene expression generated during adaptation can be accomplished by determining by high-dimensional variance partitioning within classical genetic experimental designs. A microarray experiment conducted on a panel of recombinant inbred lines (RILs) generated from two populations of Drosophila serrata that have diverged in response to natural selection, revealed genetic divergence in 10.6% of 3762 gene products examined. Over 97% of the genetic divergence in transcript abundance was explained by only 12 genetic modules. The two most important modules, explaining 50% of the genetic variance in transcript abundance, were genetically correlated with the morphological traits that are known to be under selection. The expression of three candidate genes from these two important genetic modules was assessed in an independent experiment using qRT-PCR on 430 individuals from the panel of RILs, and confirmed the genetic association between transcript abundance and morphological traits under selection.

opencc-zeroDec 2010View details →
dryad28/100

Data from: A generalized K statistic for estimating phylogenetic signal from shape and other high-dimensional multivariate data

Phylogenetic signal is the tendency for closely related species to display similar trait values due to their common ancestry. Several methods have been developed for quantifying phylogenetic signal in univariate traits and for sets of traits treated simultaneously, and the statistical properties of these approaches have been extensively studied. However, methods for assessing phylogenetic signal in high-dimensional multivariate traits like shape are less well developed, and their statistical performance is not well characterized. In this article, I describe a generalization of the K statistic of Blomberg et al. (2003) that is useful for quantifying and evaluating phylogenetic signal in highly-dimensional multivariate data. The method (Kmult) is found from the equivalency between statistical methods based on covariance matrices and those based on distance matrices. Using computer simulations based on Brownian motion, I demonstrate that the expected value of Kmult remains at 1.0 as trait variation among species is increased or decreased, and as the number of trait dimensions is increased. By contrast, estimates of phylogenetic signal found with a squared-change parsimony procedure for multivariate data change with increasing trait variation among species and with increasing numbers of trait dimensions, confounding biological interpretations. I also evaluate the statistical performance of hypothesis testing procedures based on Kmult and find that the method displays appropriate Type I error and high statistical power for detecting phylogenetic signal in high-dimensional data. Statistical properties of Kmult were consistent for simulations using bifurcating and random phylogenies, for simulations using different numbers of species, for simulations that varied the number of trait dimensions, and for different underlying models of trait covariance structure. Overall these findings demonstrate that Kmult provides a useful means of evaluating phylogenetic signal in high-dimensional multivariate traits. Finally, I illustrate the utility of the new approach by evaluating the strength of phylogenetic signal for head shape in a lineage of Plethodon salamanders.

opencc-zeroDec 2013View details →
dryad28/100

Data from: Evolutionary constraints in high-dimensional trait sets

Genetic variation for individual traits is typically abundant, but for some multivariate combinations it is very low, suggesting that evolutionary limits might be generated by the geometric distribution of genetic variance. To test this prediction, we artificially selected along all eight genetic eigenvectors of a set of eight quantitative traits in Drosophila serrata. After six generations of 50% truncation selection, at least one replicate population of all treatments responded to selection, allowing us to reject a null genetic subspace as a cause of evolutionary constraint in this system. However, while all three replicate populations of the first five selection treatments displayed a significant response, the remaining three, characterized by low genetic variance in their selection indexes in the base population, displayed inconsistent responses to selection. The observation that only four of the nine replicate populations evolved in response to the direct selection applied to them in these low genetic variance treatments, led us to conclude that a nearly null subspace did limit evolution. Dimensions associated with low genetic variance are often found in multivariate analyses of standing genetic variance in morphological traits, suggesting that the nearly null genetic subspace may be a common mechanism of evolutionary constraint in nature.

opencc-zeroDec 2013View details →
dryad28/100

Data from: ZeitZeiger: supervised learning for high-dimensional data from an oscillatory system

Numerous biological systems oscillate over time or space. Despite these oscillators' importance, data from an oscillatory system is problematic for existing methods of regularized supervised learning. We present ZeitZeiger, a method to predict a periodic variable (e.g. time of day) from a high-dimensional observation. ZeitZeiger learns a sparse representation of the variation associated with the periodic variable in the training observations, then uses maximum-likelihood to make a prediction for a test observation. We applied ZeitZeiger to a comprehensive dataset of genome-wide gene expression from the mammalian circadian oscillator. Using the expression of 13 genes, ZeitZeiger predicted circadian time (internal time of day) in each of 12 mouse organs to within ∼1 h, resulting in a multi-organ predictor of circadian time. Compared to the state-of-the-art approach, ZeitZeiger was faster, more accurate and used fewer genes. We then validated the multi-organ predictor on 20 additional datasets comprising nearly 800 samples. Our results suggest that ZeitZeiger not only makes accurate predictions, but also gives insight into the behavior and structure of the oscillator from which the data originated. As our ability to collect high-dimensional data from various biological oscillators increases, ZeitZeiger should enhance efforts to convert these data to knowledge.

opencc-zeroDec 2015View details →
dryad28/100

Data from: Permutation tests for phylogenetic comparative analyses of high-dimensional shape data: what you shuffle matters

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publicDec 2014View details →
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Data from: Surrogate modelling for the prediction of spatial fields based on simultaneous dimensionality reduction of high-dimensional input/output spaces

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publicMar 2018View details →
dryad28/100

Data from: Quantifying and comparing phylogenetic evolutionary rates for shape and other high-dimensional phenotypic data

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publicDec 2013View details →
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Data from: A generalized K statistic for estimating phylogenetic signal from shape and other high-dimensional multivariate data

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publicApr 2014View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record