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Dataset results
7 results for “homeotic transformations”
Breaking the constraint on the number of cervical vertebrae in mammals: on homeotic transformations in lorises and pottos
<p><strong>Data-collection</strong></p> <p><em>Specimens</em>. We analysed 1090 skeletons of wild-born primates belonging to 60 species of ten families (Table 1). These skeletons are held in collections of ten European and American natural history museums (Naturalis Biodiversity Center, Leiden (Naturalis); The Natural History Museum, London (NHMUK); the Royal Museum for Central Africa, Tervuren (RMCA); the Royal Belgian Institute of Natural Sciences, Brussels (RBINS); the Natural History Museum of Denmark, Copenhagen (ZMUC); Naturhistorisches Museum Wien, Vienna (NHMW); the Swedish Museum of Natural History, Stockholm (NRM); Museum fur Naturkunde, Berlin (MfN); and the National Museum for Natural History, Paris (MNHN), Natural History Museum Oslo, American Museum of Natural History, New York, Field Museum of Natural History, Chicago (FMNH). Five families belonged to the Strepsirrhini (Lorisidae, Galagidae, Daubentoniidae, Lemuridae, Indriidae) and five to the Haplorrhini, of which two Platyrrhini (Cebidae, Atelidae) and three Catarrhini (Cercopithecidae, Hylobatidae, Hominidae).</p> <p><strong>Cervical vertebrae and transitional cervicothoracic vertebrae</strong>. We determined the number of cervical vertebrae and transitional cervicothoracic vertebrae (vertebrae with both cervical and thoracic characteristics, i.e. a seventh vertebrae with a rudimentary rib or one full rib instead of two, or an eighth vertebrae with rudimentary ribs or without ribs on one side). The identification of transitional cervicothoracic vertebrae was based on the presence of cervical or rudimentary first ribs. In the case of a fusion of rudimentary cervical ribs with the transverse process (apophysomegaly), the vertebra was counted as a transitional cervicothoracic vertebra when the transverse process was at least 15% longer than that of the first thoracic vertebra, or when traces of the articulation were still visible.</p> <p><strong>Explanatory variables. </strong>Per specimen where we determined the vertebral pattern, we recorded the species, life style ("fast" vs. "slow"), individual age class and sex and whether the animal was kept in a zoo later in life or not. This last indicator variable can accommodate effects of relaxed selection in captive environments on the probability of finding an abnormal pattern.</p> <p><strong>Phylogeny. </strong>We used the consensus phylogeny of primates provided by the 10k Trees Project (Arnold & Nunn, 2010) to represent our data per species graphically and to calculate correlations between species effects</p> <p><strong>Statistical analysis. </strong>The R script with our analysis is added.</p> <p> </p>
Targeted disruption of Hotair leads to homeotic transformation and de-repression of imprinted genes [RNA-Seq, ChIP-Seq]
GEO Series GSE48005. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Integrated epigenome, exome and transcriptome analyses reveal molecular subtypes and homeotic transformation in uterine fibroids [DNA methylation]
GEO Series GSE120854. Homo sapiens. 34 samples. Type: Methylation profiling by array.
Integrated epigenome, exome and transcriptome analyses reveal molecular subtypes and homeotic transformation in uterine fibroids
GEO Series GSE135446. Homo sapiens. 22 samples. Type: Methylation profiling by array.
HOX epi-mutations, driven by maternal SMCHD1 or LRIF1 haploinsufficiency, trigger homeotic transformations in genetically wildtype offspring
GEO Series GSE173462. Danio rerio. 12 samples. Type: Expression profiling by high throughput sequencing.
Targeted disruption of Hotair leads to homeotic transformation and de-repression of imprinted genes [Microarray Analysis]
GEO Series GSE48004. Mus musculus. 6 samples. Type: Expression profiling by array.
Targeted disruption of Hotair leads to homeotic transformation and de-repression of imprinted genes
GEO Series GSE48007. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.