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ShareScore release 0.9.0
Dataset results
493 results for “human breast cancer”
Phindr3D: Test Data Set 2 (human MCF10A breast cancer organoids)
<p>3D confocal image stacks of human MCF10A breast cancer organoids expressing different oncogenes to test the functionality of Phindr3D. Explanatory .txt file contained in the ZIP files.</p> <p>Please see the manuscript for details and on how to access the full data set:</p> <p> </p> <p><strong>Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning</strong></p> <p>Philipp Mergenthaler*, Santosh Hariharan*, James M. Pemberton, Corey Lourenco, Linda Z. Penn, David W. Andrews</p> <p><em>PLOS Computational Biology, DOI: <a href="https://dx.doi.org/10.1371/journal.pcbi.1008630">10.1371/journal.pcbi.1008630</a></em></p> <p> </p> <p><strong>Phindr3D is available on GitHub</strong>: <a href="https://github.com/DWALab/Phindr3D">GitHub - DWALab/Phindr3D</a></p>
DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03]
ClinicalTrials.gov study NCT03529110. IPD Sharing: YES. Countries: 15. Publications: 9.
Phase I/II Study of U3-1402 in Subjects With Human Epidermal Growth Factor Receptor 3 (HER3) Positive Metastatic Breast Cancer
ClinicalTrials.gov study NCT02980341. IPD Sharing: YES. Countries: 2. Publications: 1.
Human breast cancer PDTX models bulk and single cell RNA sequencing
<p>This dataset includes information relevant to the following manuscript from the labs of Prof. Carlos Caldas (University of Cambridge), and Dr. Long V. Nguyen (Princess Margaret Cancer Centre, University Health Network):</p> <p>Nguyen LV et al. Dynamics and plasticity of human breast cancer single cell-derived clones. Under consideration for publication.</p> <p>Bulk RNA sequencing raw count matrices are provided (RawCounts.csv) along with the normalized count matrices (LogCPMNormCounts.csv).</p> <p>Single cell RNA sequencing count matrix processed from R package metacell is provided (mat.pdx_LN_v2_filt.Rda), along with the mc and mc2d files with information on metacell partitions (mc.pdx_LN_v2_filt.Rda and mc2d.pdx_LN_v2_filt.Rda).</p> <p>Single cell RNA sequencing count matrices processed using Seurat are also provided separately for each PDTX model analysed (STG139.rds, STG201.rds, AB040.rds and IC07.rds).</p> <p>Code and information on data analysis is provided for reviewers in our unpublished manuscript and on Github (https://github.com/cclab-brca/clone-dynamics).</p>
Safety, Tolerability, and Pharmacokinetic (PK) Study of DHES0815A in Participants With Human Epidermal Growth Factor Receptor (HER)2-Positive Breast Cancer
ClinicalTrials.gov study NCT03451162. IPD Sharing: Not stated. Countries: 2. Publications: 1.
A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer
ClinicalTrials.gov study NCT01358877. IPD Sharing: YES. Countries: 42. Publications: 9.
Lux-Breast 3; Afatinib Alone or in Combination With Vinorelbine in Patients With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer Suffering From Brain Metastases
ClinicalTrials.gov study NCT01441596. IPD Sharing: Not stated. Countries: 8. Publications: 1.
A Study of Herceptin (Trastuzumab) in Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Advanced and/or Metastatic Breast Cancer
ClinicalTrials.gov study NCT02748213. IPD Sharing: Not stated. Countries: 15. Publications: 1.
A Study of Single-Agent Eribulin Mesylate as First-Line Therapy for Locally Recurrent or Metastatic Human Epidermal Growth Factor Receptor Two (HER2) Negative Breast Cancer
ClinicalTrials.gov study NCT01268150. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of Pertuzumab in Combination With Trastuzumab (Herceptin) and a Taxane in First-Line Treatment in Participants With Human Epidermal Growth Factor 2 (HER2)-Positive Advanced Breast Cancer
ClinicalTrials.gov study NCT01572038. IPD Sharing: Not stated. Countries: 39. Publications: 1.
A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer Who Have Received Prior Anti-HER2 And Chemotherapy-based Treatment
ClinicalTrials.gov study NCT01702571. IPD Sharing: Not stated. Countries: 43. Publications: 3.
A Study of H3B-6545 in Combination With Palbociclib in Women With Advanced or Metastatic Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor-2 (HER2)-Negative Breast Cancer
ClinicalTrials.gov study NCT04288089. IPD Sharing: YES. Countries: 2. Publications: 1.
A Study of Eribulin Mesylate With Trastuzumab for Advanced or Recurrent Human Epidermal Growth Factor Receptor 2-Positive (HER2+) Breast Cancer
ClinicalTrials.gov study NCT01432886. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Participant Preference of Subcutaneous (SC) Versus Intravenous (IV) Herceptin (Trastuzumab) in Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer
ClinicalTrials.gov study NCT01401166. IPD Sharing: Not stated. Countries: 12. Publications: 5.
Trastuzumab and RAD001 in Patients With Human Epidermal Growth Receptor 2 (HER-2) Overexpressing Breast Cancer
ClinicalTrials.gov study NCT00317720. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study in Participants With Early-Stage or Locally Advanced Human Epidermal Growth Factor Receptor (HER) 2-Positive Breast Cancer to Evaluate Treatment With Trastuzumab Plus (+) Pertuzumab + Docetaxel
ClinicalTrials.gov study NCT02586025. IPD Sharing: Not stated. Countries: 4. Publications: 1.
A Study of Subcutaneous At Home Administration of Trastuzumab (Herceptin) in Participants With Human Epidermal Growth Factor Receptor 2-positive (HER2+) Early Breast Cancer (eBC)
ClinicalTrials.gov study NCT01926886. IPD Sharing: Not stated. Countries: 2. Publications: 1.
A Study of Pertuzumab and Trastuzumab Subcutaneous (SC) Treatment in Combination With a Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer
ClinicalTrials.gov study NCT02019277. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Neoadjuvant Endocrine Therapy in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Node-Negative Breast Cancer
ClinicalTrials.gov study NCT03219476. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study of the Safety of Subcutaneously Administered Trastuzumab (Herceptin) in Participants With Early and Locally Advanced Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
ClinicalTrials.gov study NCT01940497. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.