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273 results for “master regulators”
Layer 1 NDNF Interneurons are Specialized Top-Down Master Regulators of Cortical Circuits, Part 1/3
<p>Associated data and code for Hartung et al. "Layer 1 NDNF Interneurons are Specialized Top-Down Master Regulators of Cortical Circuits".</p> <ul> <li>This is repository 1/3 and contains all code generated for and used in the paper.</li> <li>This repository contains all data for figures 1, 2 & 4-6 of the paper, as well as electrophysiological data for figure 3.</li> <li>Histological data for figure 3 can be found in repositories 2/3 (10.5281/zenodo.10938467) and 3/3 (10.5281/zenodo.10938471).</li> <li>The code can alternatively also be accessed via GitHub: https://github.com/janH-21/NDNF-interneurons-cortical-circuits</li> <li>Please consider citing our paper if you use our data or code (see GitHub repository for link).</li> <li>Please refer to the README file for orientation and contact JH or JJL if you have further questions (see paper for contact details).</li> </ul>
Layer 1 NDNF Interneurons are Specialized Top-Down Master Regulators of Cortical Circuits, Part 2/3
<p>Associated data for Hartung et al. "Layer 1 NDNF Interneurons are Specialized Top-Down Master Regulators of Cortical Circuits".</p> <ul> <li>This is repository 2/3 and contains histological data for figure 3.</li> <li>Repository 1/3 (10.5281/zenodo.10938947) contains all data for figures 1, 2 & 4-6 of the paper, as well as electrophysiological data for figure 3.</li> <li>Repository 1/3 (10.5281/zenodo.10938947) contains all code generated for and used in the paper. </li> <li>Repository 3/3 (10.5281/zenodo.10938471) contains additional histological data for figure 3.</li> <li>The code can alternatively also be accessed via GitHub: https://github.com/janH-21/NDNF-interneurons-cortical-circuits</li> <li>Please consider citing our paper if you use our data or code (see GitHub repository for link).</li> <li>Please refer to the README file for orientation and contact JH or JJL if you have further questions (see paper for contact details).</li> </ul>
Layer 1 NDNF Interneurons are Specialized Top-Down Master Regulators of Cortical Circuits, Part 3/3
<p>Associated data for Hartung et al. "Layer 1 NDNF Interneurons are Specialized Top-Down Master Regulators of Cortical Circuits".</p> <ul> <li>This is repository 3/3 and contains histological data for figure 3.</li> <li>Repository 1/3 (10.5281/zenodo.10938947) contains all data for figures 1, 2 & 4-6 of the paper, as well as electrophysiological data for figure 3.</li> <li>Repository 1/3 (10.5281/zenodo.10938947) contains all code generated for and used in the paper. </li> <li>Repository 3/3 (10.5281/zenodo.10938467) contains additional histological data for figure 3.</li> <li>The code can alternatively also be accessed via GitHub: https://github.com/janH-21/NDNF-interneurons-cortical-circuits</li> <li>Please consider citing our paper if you use our data or code (see GitHub repository for link).</li> <li>Please refer to the README file for orientation and contact JH or JJL if you have further questions (see paper for contact details).</li> </ul>
Data from: The non-coding RNA CcnA modulates the master cell cycle regulators CtrA and GcrA in Caulobacter crescentus
<p>Bacteria are powerful models for understanding how cells divide and accomplish global regulatory programs. In <em>Caulobacter crescentus</em>, a cascade of essential master regulators supervises the correct and sequential activation of DNA replication, cell division and development of different cell types. Among them, the response regulator CtrA plays a crucial role coordinating all those functions. Here, for the first time we describe the role of a novel factor named CcnA, a cell cycle regulated ncRNA located at the origin of replication, presumably activated by CtrA and responsible for the accumulation of CtrA itself. In addition, CcnA may be also involved in the inhibition of translation of the S-phase regulator, GcrA, by interacting with its 5' untranslated region (5'-UTR). Performing <em>in vitro</em> experiments and mutagenesis, we propose a mechanism of action of CcnA based on liberation (<em>ctrA</em>) or sequestration (<em>gcrA</em>) of their ribosome-binding site (RBS). Finally, its role may be conserved in other alphaproteobacterial species, such as <em>Sinorhizobium</em> <em>meliloti</em>, representing indeed a potentially conserved process modulating cell cycle in <em>Caulobacterales </em>and<em> Rhizobiales</em>. </p>
Data from: The non-coding RNA CcnA modulates the master cell cycle regulators CtrA and GcrA in Caulobacter crescentus
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Data from: Control of relative timing and stoichiometry by a master regulator
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MUC1-C IS A MASTER REGULATOR OF MICA/B NKG2D LIGAND AND EXOSOME SECRETION IN HUMAN CANCER CELLS
GEO Series GSE215308. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Akr1b7 functions as a master regulator in ovarian aging [RNA-seq]
GEO Series GSE238259. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
Inhibitor of DNA binding-1, a master regulator of vasculogenic mimicry by cancer cells.
GEO Series GSE272838. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype - mouse RNAseq experiments
GEO Series GSE145556. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Foxi2 and Sox3 are master regulators controlling ectoderm germ layer specification in Xenopus [RNA-Seq]
GEO Series GSE288636. Xenopus tropicalis. 18 samples. Type: Expression profiling by high throughput sequencing.
Transmural pressure is a master regulator of airway branching morphogenesis
GEO Series GSE90148. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
An integrative transcriptomics approach identifies miR-503 as a candidate master regulator of the estrogen response [miRNA-seq]
GEO Series GSE78168. Homo sapiens. 30 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Next generation sequencing facilitates quantitative analysis of changes in mRNA after knock-down of putative master regulators of the breast cancer metastasis transcriptome.
GEO Series GSE79586. Homo sapiens. 128 samples. Type: Expression profiling by high throughput sequencing.
Cistrome-partitioning reveals convergence of somatic mutations and risk-variants on master transcription regulators in primary prostate tumors
GEO Series GSE137527. Homo sapiens. 48 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The Negative Cofactor 2 complex is a master regulator of drug resistance in Aspergillus fumigatus [RNA-seq]
GEO Series GSE133464. Aspergillus fumigatus. 18 samples. Type: Expression profiling by high throughput sequencing.
BET Bromodomain Inhibition Blocks the Function of a Critical AR-Independent Master Regulator Network in Lethal Prostate Cancer
GEO Series GSE98069. Homo sapiens. 34 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
A Transcriptional Regulatory Loop of Master Regulator Transcription Factors, PPARG, and Fatty Acid Synthesis Promotes Esophageal Adenocarcinoma
GEO Series GSE143195. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Musashi-1 is a master regulator of aberrant translation in Group 3 medulloblastoma
GEO Series GSE126337. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer
GEO Series GSE131857. Homo sapiens. 23 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.