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15 results for “melanogenesis”
Data from: Pleiotropy in the melanocortin system: expression levels of this system are associated with melanogenesis and pigmentation in the tawny owl (Strix aluco)
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Srebf1-mediated fatty acid metabolism is crucial to sustain sugmented pigmentation SREBF1-mediated metabolic reprogramming through fatty acid metabolism sustains augmented melanogenesis
GEO Series GSE164375. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Heat promotes melanogenesis by increasing the paracrine effects in keratinocytes via the TRPV3/Ca2+/Hh signaling pathway
GEO Series GSE229915. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis
GEO Series GSE93657. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
PAX6 Regulates Melanogenesis in the Retinal Pigmented Epithelium through Feed-Forward Regulatory Interactions with MITF
GEO Series GSE56548. Mus musculus. 6 samples. Type: Expression profiling by array.
Modelling of pigmentation disorders associated with MITF mutation in Waaredenburg Syndrome revealed an impaired melanogenesis pathway in iPS-derived melanocytes
GEO Series GSE200674. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Artificial Melanogenesis by Confining Melanin/Polydopamine Production Inside Polymersomes
<p>Data underlying the figures in the publication “Artificial melanogenesis by confining melanin/polydopamine production inside polymersomes”, published in <em>Macromolecular Bioscience, </em><strong>2021</strong>.</p> <p>Table of contents:</p> <p><strong>1. Figure 1</strong>; Zip. archive containing the experimental data for <em>Figure 1</em>. TEM micrographs and corresponding DLS and SLS revealing the morphology and size of (A) Melanin-polymersomes (with Tyrosinase), (B) PDA-polymersomes (with Tyrosinase), (C) empty polymersomes rehydrated with PBS only, and (D) Tyrosinase-polymersomes.</p> <p><strong>2. Figure 2</strong>; Zip. archive containing the experimental data for <em>Figure 2</em>. (A) Zeta potential values showing the absence of Dopamine, L-DOPA or Tyrosinase adsorption at the surface of polymersomes. TEM micrographs of polymersome clusters formed after adding (B) L-DOPA with Tyrosinase, (C) Dopamine with Tyrosinase, (D) L-DOPA and (E) Dopamine to empty polymersomes.</p> <p><strong>3. Figure 3</strong>; Zip. archive containing the experimental data of the graphs in <em>Figure 3</em>. Melanin and PDA formation within polymersomes monitored via UV-vis spectroscopy. Absorption spectra measured at t = 0 (grey), t=12 h (cyan) and t=24 h (orange) of incubation at 37 °C of (A) Empty polymersomes, (B) Tyrosinase polymersomes, (C) L-DOPA polymersomes, (D) L-DOPA polymersomes (with Tyrosinase), (E) Dopamine polymersomes, (F) Dopamine polymersomes (with Tyrosinase).</p> <p><strong>4. Figure 4</strong>; Zip. archive containing the experimental data for <em>Figure 4</em>. Interaction of polymersome-based melanosome mimics with HaCaT cells. (A) Cell proliferation assay showing the non-toxicity of different polymersomes encapsulating dopamine and Tyrosinase (dashed purple), L-DOPA and Tyrosinase (dashed grey), dopamine (purple), L-DOPA (grey), PBS (yellow), Tyrosinase (dashed yellow) compared to control PBS without polymersomes (blue). Cells were incubated with respective polymersomes for 24 h. (B) Cell proliferation assay showing the cytotoxicity of free L-DOPA/dopamine (with and without Tyrosinase) compared to PBS. (C) Cell proliferation assay showing the cytotoxicity/cell protection effect of different kinds of polymersomes after 40 min of UV-irradiation of cells treated for 24 h with polymersomes. (D) CLSM images showing perinuclear localization of model polymersomes (encapsulating fluorescent Atto-488) in keratinocytes. Statistical significance was shown as p values < 0.02.</p> <p> </p>
A systematic exploration reveals the potential of spermidine for hypopigmentation treatment through the stabilization of melanogenesis-associated proteins
GEO Series GSE209538. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptional profiling shows altered expression of wnt pathway- and lipid metabolism-related genes as well as melanogenesis-related genes in melasma.
GEO Series GSE72140. Homo sapiens. 48 samples. Type: Expression profiling by array.
Genotypic and gene expression studies in Congenital Melanocytic Nevi: insight into initial step of tumoral melanogenesis
GEO Series GSE8525. Homo sapiens. 12 samples. Type: Expression profiling by array.
Melanocyte and nerve fiber cross-talk enhances UV-B-induced melanogenesis in human epidermis and is facilitated by semaphorin-4A
GEO Series GSE271182. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
IL-17 and TNF synergistically induce growth-associated cytokines in melanocytes while suppressing melanogenesis
GEO Series GSE40413. Homo sapiens. 12 samples. Type: Expression profiling by array.
Investigating the function of Sox10 in avian melanogenesis
GEO Series GSE247549. Columba livia. 23 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Long non-coding RNA Mir17hg positively regulates melanogenesis by inhibiting TGFβ receptor 2 under psychological stress
GEO Series GSE241826. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Polianthes tuberosa L. Extract Suppresses Melanogenesis through Concurrent Inhibition of cAMP/CREB and MAPK Signaling Pathways
GEO Series GSE315802. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.