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5 results for “nucleoside phosphorylases”
Supplementary Information for "Nucleoside Phosphorylases Make N7-Xanthosine, a "Non native" Regioisomer of Xanthosine"
<p>This is the external Supplementary Information for our publication "Nucleoside Phosphorylases Make N7-Xanthosine, a "Non native" Regioisomer of Xanthosine".</p> <p>The .pdf file contains the Supplementary Information: author contributions, accessibility statement, experimental procedures, and supplementary items, among others.</p> <p>The .zip file contains the raw data and metadata for all items (supplementary and main text) as well as the calculation results. This includes UV, HPLC, NMR, HRMS, and DFT results. The full set of raw HPLC chromatograms is - unfortunately - only available to us in a proprietary file format but we are happy to share these data upon request. This revised version contains additional UV data on experiments excluding oxidation of xanthine to uric acid as well as additional NMR data on purified N7-xanthosine and reference data for N9-xanthosine and xanthine in D2O.</p> <p>To some extent, this work builds on and borrows from our previous publications on spectral unmixing (https://doi.org/10.3390/mps2030060, https://doi.org/10.1002/cbic.202000204), continuous reaction monitoring (https://doi.org/10.1021/acs.analchem.1c05356), and thermodynamic reaction control (https://doi.org/10.1002/adsc.201901230, https://doi.org/10.5281/zenodo.3568858, https://doi.org/10.1002/cphc.202000901, https://doi.org/10.1021/acscatal.1c02589).</p>
Supplementary Material for "General Principles for Yield Optimization of Nucleoside Phosphorylase-Catalyzed Transglycosylations"
<p>This is the supplementary material for our publication "General Principles for Yield Optimization of Nucleoside Phosphorylase-Catalyzed Transglycosylations".</p> <p>The .pdf file contains the supplementary information: Author Contributions, Conflict of Interest, Sample analysis by HPLC, Table S1 and S1, Figure S1 and a suggested workflow for NPase-catalyzed nucleoside synthesis.</p> <p>The .xlsx file contains an implementation of the simplified formula for yield prediction (equation (4) ), using previously reported thermodynamic data (10.5281/zenodo.3459298).</p> <p>The Python code and all data calculated from numerical solutions of the system of equilibrium constraints is available elsewhere (10.5281/zenodo.3522588).</p>
Supplementary Information for "The Peculiar Case of the Hyperthermostable Pyrimidine Nucleoside Phosphorylase from Thermus thermophilus"
<p>This is the external Supplementary Information for our publication "The Peculiar Case of the Hyperthermostable Pyrimidine Nucleoside Phosphorylase from <em>Thermus thermophilus</em>".</p> <p>The .pdf file contains the Supplementary Information: author contributions, experimental procedures and supplementary items.</p> <p>The .zip file contains the raw data and metadata for all items (supplementary and main text) and the calculations.</p> <p>The Python code used for spectral unmixing is available on this platform (10.5281/zenodo.3243376) and has been described in our previous publications (10.3390/mps2030060, 10.5281/zenodo.3333469, 10.1002/cbic.202000204, 10.5281/zenodo.3723806 ). Further applications of this method can be found in our recent article in <em>Adv. Synth. Catal.</em> (10.1002/adsc.201901230) and its supporting material (10.5281/zenodo.3568858).</p>
Supplementary Information for "Biased Borate Esterification during Nucleoside Phosphorylase-Catalyzed Reactions: Apparent Equilibrium Shifts and Kinetic Implications"
<p>This is the external Supplementary Information for our publication "Biased Borate Esterification during Nucleoside Phosphorylase-Catalyzed Reactions: Apparent Equilibrium Shifts and Kinetic Implications".</p> <p>The .zip files contains the raw data and metadata for all items (supplementary and main text) as well as the calculation results. This includes UV, HPLC, NMR, DFT and MD results. This revised version presents extended DFT results (now including dispersion contributions) as well as additional NMR data (now including analytical data for isolated 1f, among other data).</p> <p>To some extent, this work builds on and borrows from our previous publications on spectral unmixing (https://doi.org/10.3390/mps2030060, https://doi.org/10.1002/cbic.202000204), continuous reaction monitoring (https://doi.org/10.1021/acs.analchem.1c05356), and thermodynamic reaction control (https://doi.org/10.1002/adsc.201901230, https://doi.org/10.5281/zenodo.3568858, https://doi.org/10.1002/cphc.202000901, https://doi.org/10.1021/acscatal.1c02589).</p>
Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity
GEO Series GSE203003. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.