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Dataset results
91 results for “orofacial”
Topiramate inhibits adjuvant-induced chronic orofacial inflammatory allodynia in the rat
<p>The uploaded data are the raw data from the accepted article "Topiramate inhibits adjuvant-induced chronic orofacial inflammatory allodynia in the rat", published in Frontiers in Pharmacology. </p> <p> </p>
An over-dominant effect associated with an SNP in a TP63 regulatory region is implicated in susceptibility to non-syndromic orofacial clefts.
<p><strong>Background</strong>: Non-syndromic orofacial clefts (NSOC) are complex phenotypes, involving multiple low penetrance genetic and environmental factors. Using a candidate gene approach, we aimed to analyze the role of four single nucleotide polymorphisms (SNPs) in the susceptibility to NSOC.</p> <p><strong>Methods</strong>: A total of 254 individuals, 120 patients with NSOC, and 134 controls, all of Portuguese origin and non-consanguineous, were recruited. About 92% of patients had cleft lip with or without cleft palate (NSCL/P) and 8% had cleft palate (NSCP). Four SNPs in the <em>MTHFR</em>, <em>IRF6</em>, <em>PAX7,</em> and <em>TP63</em> genes were studied, using a real-time approach with TaqMan probes. Statistical analysis was performed with IBM SPSS Statistics and included chi-squared, Cochran test for trend and binomial logistic regression. Bonferroni correction was applied. Statistical significance was set to 0.05.</p> <p><strong>Results: </strong>All SNPs were in Hardy-Weinberg equilibrium. A significant statistical association was found for <em>TP63</em> rs9332461 in an over-dominant model (<em>p</em> = 0.016; OR 1.897 (1.144 - 3.147)).</p> <p><strong>Discussion and conclusion</strong>: Few SNPs have been so far identified in <em>TP63</em> in population association studies. In our sample, a significant association was only highlighted for rs9332461, localized in upstream regulatory region. Mechanisms involved in heterozygous advantage may underlie the association. </p>
Data set for "Neural mechanisms underlying uninstructed orofacial movements during reward-based learning tasks"
<p>Data set for Li, Nakano, et al. (2023) Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors. Current Biology, https://doi.org/10.1016/j.cub.2023.07.013</p> <p><br> The file "Li_Nakano_et_al_detaset.zip" (~45.4 GB) is a compressed version of the "Li_Nakano_et_al_detaset" folder. The uncompressed folder (~76.4 GB) houses the data and some analytical codes used in the study. Upon extraction, the folder reveals two subfolders, "Raw data" and "Source data," and a 'README' text file providing further instructions or information.</p>
Study of Orofacial Pain and PropRANOlol
ClinicalTrials.gov study NCT02437383. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Evaluation of the Efficacy of Neuromodulation in the Control of Chronic Orofacial Pain
ClinicalTrials.gov study NCT07352384. IPD Sharing: NO. Countries: 1. Publications: 6.
Acute Effects of Alcohol Use on Chronic Orofacial Pain
ClinicalTrials.gov study NCT04019093. IPD Sharing: NO. Countries: 1. Publications: 1.
Study of a New Technique to Improve the Symptoms of Orofacial Discomfort in Patients With Peripheral Facial Paralysis
ClinicalTrials.gov study NCT01327157. IPD Sharing: NO. Countries: 1. Publications: 5.
An Innovative Cognitive-Behavioral Treatment For Chronic Orofacial Pain
ClinicalTrials.gov study NCT07123233. IPD Sharing: NO. Countries: 1. Publications: 6.
Trial to Compare the Effects of Myo Munchee Therapy and Oral Motor Therapy (OMT) in Pediatric Patients to Treat Maxillary Deficiency and Orofacial Myofunctional Dysfunction (OMD).
ClinicalTrials.gov study NCT07088055. IPD Sharing: NO. Countries: 1. Publications: 1.
Effectiveness of Low-Level Laser Therapy (LLLT) Versus Orofacial Physical Therapy for Temporomandibular Dysfunction. a Randomized Controlled Trial
ClinicalTrials.gov study NCT06772012. IPD Sharing: NO. Countries: 1. Publications: 1.
Orofacial Functions in Individuals With and Without Molar Incisor Hypomineralization
ClinicalTrials.gov study NCT06692257. IPD Sharing: Not stated. Countries: 0. Publications: 1.
BBTI vs PSR in Musculoskeletal Orofacial Pain Adults
ClinicalTrials.gov study NCT04897581. IPD Sharing: NO. Countries: 1. Publications: 1.
Effects of Orofacial Myofunctional Therapy on Mental Functioning and Overall Self-Sufficiency in Stroke Patients
ClinicalTrials.gov study NCT05061043. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Orofacial Development of Preterm and Low Birthweight Infants Versus Term Infants
ClinicalTrials.gov study NCT00408746. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain
ClinicalTrials.gov study NCT03766464. IPD Sharing: NO. Countries: 1. Publications: 0.
Additional Effect of Pain Neuroscience Education to Orofacial and Neck Exercises in Temporomandibular Disorders
ClinicalTrials.gov study NCT03926767. IPD Sharing: NO. Countries: 1. Publications: 2.
Study on the Effect of Granisetron on Myofascial Pain in the Orofacial Muscles
ClinicalTrials.gov study NCT02230371. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Effect of Orofacial Myofunctional Therapy on Mouth Air Leak in Patients With Sleep Apnea Treated With CPAP
ClinicalTrials.gov study NCT05432908. IPD Sharing: NO. Countries: 1. Publications: 5.
Oral Habits Effect on Orofacial Dysfunction and Oral Health Related Quality of Life.
ClinicalTrials.gov study NCT04575792. IPD Sharing: UNDECIDED. Countries: 1. Publications: 5.
Development of the Palate in Bilateral Orofacial Cleft Newborns One Year After Early Neonatal Cheiloplasty
ClinicalTrials.gov study NCT03839290. IPD Sharing: NO. Countries: 1. Publications: 3.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.